(a.) Not accessible; not to be reached, obtained, or approached; as, an inaccessible rock, fortress, document, prince, etc.
Example Sentences:
(1) Two-thirds of the cytoplasmic water is inaccessible to sucrose and is designated c2.
(2) These are usually located in the intracranial part of the vertebral artery and less frequently in the lower basilar artery, and are therefore inaccessible to prophylactic vascular surgery.
(3) Unfortunately, transitional cell carcinoma may involve other regions of the prostate that are inaccessible by cystoscopy.
(4) Acquisition of Ab inaccessibility occurred very efficiently in this cell-free system (approximately 50% of total cell-associated 125I-BSST became inaccessible) and could be inhibited by anti-clathrin mAbs and by antibodies directed against the cytoplasmic domain of the transferrin-receptor.
(5) Inaccessibility of essential health information to the women most affected, and the physical as well as economic and sociocultural distance separating health services from the vast majority of women, are only part of the problem.
(6) It also provides important details about potential surgical routes to this relatively inaccessible region.
(7) Bypass of surgically inaccessible stenoses or occlusions appears to be a logical technique to prevent future stroke but there is much uncertainty about the clinical indications for surgery and even the natural history of the lesions being bypassed.
(8) In 2019, the long-awaited Crossrail project is due to open, but up until a few weeks ago, seven of the 38 stations on the route were set to remain inaccessible.
(9) Because of the mild and focal nature of the inflammatory infiltrates and involvement of regions inaccessible to the bioptome, sampling error contributes appreciably to false-negative results in endomyocardial biopsy tissue from patients with myocarditis.
(10) The dissociation constant of ATP from the unligated enzyme, a constant that has previously been experimentally inaccessible, has been measured for wild-type and several mutant enzymes.
(11) We must urgently tackle this culture of inaccessible politics.
(12) The problems faced in the prevention and control of malaria include problems associated with the opening of land for agriculture, mobility of the aborigines of Peninsular Malaysia (Orang Asli) and inaccessibility of malaria problem areas.
(13) However, in less than 15 sec, LTB4-treated PMN lose the ability to respond further to LTB4; decrease the affinity and number of high affinity receptors available for binding LTB4; sequester LTB4 in plasmalemma-associated sites that are inaccessible to a releasing buffer regimen; and begin internalizing LTB4.
(14) The species-specific inactivation in concluded from various lines of evidence to be ATP-site-directed and is attributed to alkylation of an amino acid residue of the rabbit enzyme which in the pig and carp enzymes is absent, inaccessible, or less reactive.
(15) Because the three major proteins of the Karp and Gilliam strains are accessible to antibody in unextracted organisms, it is possible that the exteriorly exposed epitopes of these three polypeptides are strain specific and that their common determinants are normally buried in the membrane or otherwise inaccessible.
(16) This decrease in PI-PLC sensitivity may reflect an alteration in the PI-glycan anchoring structures, or in a general membrane property, which renders the PI-anchored proteins inaccessible to the enzyme.
(17) A deficit in, or the inaccessibility of, J chain protein appears to facilitate hexamer formation.
(18) We have already introduced a vacuum drainage system, which is a special drainage system through a machine that removes water, but we cannot do anything about the climate of the Amazon.” Bastos went on to outline the problems with maintaining a pitch in such an inaccessible part of Brazil.
(19) We discuss the possibility that a shift in equilibrium between accessible and inaccessible transporters is operating.
(20) One of the physiological consequences of these interactions is that polymorphonuclear leukocytes stimulated with either chemoattractants or TNF form protected compartments at their interface with fibrinogen-coated surfaces and that elastase released into these compartments is inaccessible to protease inhibitors present in the plasma.
Reach
Definition:
(v. i.) To retch.
(n.) An effort to vomit.
(v. t.) To extend; to stretch; to thrust out; to put forth, as a limb, a member, something held, or the like.
(v. t.) Hence, to deliver by stretching out a member, especially the hand; to give with the hand; to pass to another; to hand over; as, to reach one a book.
(v. t.) To attain or obtain by stretching forth the hand; to extend some part of the body, or something held by one, so as to touch, strike, grasp, or the like; as, to reach an object with the hand, or with a spear.
(v. t.) To strike, hit, or touch with a missile; as, to reach an object with an arrow, a bullet, or a shell.
(v. t.) Hence, to extend an action, effort, or influence to; to penetrate to; to pierce, or cut, as far as.
(v. t.) To extend to; to stretch out as far as; to touch by virtue of extent; as, his land reaches the river.
(v. t.) To arrive at; to come to; to get as far as.
(v. t.) To arrive at by effort of any kind; to attain to; to gain; to be advanced to.
(v. t.) To understand; to comprehend.
(v. t.) To overreach; to deceive.
(v. i.) To stretch out the hand.
(v. i.) To strain after something; to make efforts.
(v. i.) To extend in dimension, time, amount, action, influence, etc., so as to touch, attain to, or be equal to, something.
(v. i.) To sail on the wind, as from one point of tacking to another, or with the wind nearly abeam.
(n.) The act of stretching or extending; extension; power of reaching or touching with the person, or a limb, or something held or thrown; as, the fruit is beyond my reach; to be within reach of cannon shot.
(n.) The power of stretching out or extending action, influence, or the like; power of attainment or management; extent of force or capacity.
(n.) An extended portion of land or water; a stretch; a straight portion of a stream or river, as from one turn to another; a level stretch, as between locks in a canal; an arm of the sea extending up into the land.
(n.) An artifice to obtain an advantage.
(n.) The pole or rod which connects the hind axle with the forward bolster of a wagon.
Example Sentences:
(1) Philip Shaw, chief economist at broker Investec, expects CPI to hit 5.1%, just shy of the 5.2% reached in September 2008, as the utility hikes alone add 0.4% to inflation.
(2) The final number of fibers--140,000-165,000--is reached by the sixth week after birth.
(3) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(4) Here we show that this induction of AP-2 mRNA is at the level of transcription and is transient, reaching a peak 48-72 hr after the addition of RA and declining thereafter, even in the continuous presence of RA.
(5) The peak molecular weight never reached that of a complete 2:1 complex.
(6) After vascular injury, smooth muscle cells proliferate, reaching a maximum rate at day 2.
(7) Since the start of this week, markets have been more cautious, with bond yields in Spain reaching their highest levels in four months on Tuesday amid concern about the scale of the austerity measures being imposed by the government and fears that the country might need a bailout.
(8) Both development of EDTA-resistant fibrinogen binding and fibrinogen association with the cytoskeleton were time dependent and reached maxima 45 to 60 minutes after fibrinogen binding to stimulated platelets.
(9) Foetal serum TSH concentration declined significantly between 20 and 21 days of gestation, reached a low level at delivery, and remained low for several days after birth.
(10) The highest antishock effect of dopamine is reached when cardiac output fraction addressed to thoracic region vitals is supported by dopamine on the 43-45% level.
(11) Earlier this month, Khamenei insisted that all sanctions be lifted immediately on a deal being reached, a condition that the US State Department dismissed.
(12) This indicates that [Ca2+]i may reach greater than 10 microM during an RCC.
(13) Keep it in the ground campaign Though they draw on completely different archives, leaked documents, and interviews with ex-employees, they reach the same damning conclusion: Exxon knew all that there was to know about climate change decades ago, and instead of alerting the rest of us denied the science and obstructed the politics of global warming.
(14) The move to an alliance model is not only to achieve greater scale and reach, although growing from 15 partner organisations to 50 members is not to be sniffed at.
(15) It is possible that the elements provide common precursor proteins that reach the secretory intermediate lobe cells through their dendritic branches.
(16) More evil than Clocky , the alarm clock that rolls away when you reach out to silence it, or the Puzzle Alarm , which makes you complete a simple puzzle before it'll go quiet, the Money Shredding Alarm Clock methodically destroys your cash unless you rouse yourself.
(17) A failure to reach a solution would potentially leave 200,000 homes without affordable cover, leaving owners unable to sell their properties and potentially exposing them to financial hardship.
(18) These O2-exposed cells were resistant to 4HNE, requiring 2.6 times as long in 80 microM 4HNE to reach 30% survival as compared to density-matched normoxia control.
(19) But the amount of time spent above SPA has differed substantially between men and women due to women both living longer, and reaching state pension age earlier.
(20) He said the 8.13am train from the French capital to London reached Calais before suffering “network problems”.