(n.) Freedom from that which pains, or harasses, as toil, care, grief, etc.
(n.) The quality or condition of being indolent; inaction, or want of exertion of body or mind, proceeding from love of ease or aversion to toil; habitual idleness; indisposition to labor; laziness; sloth; inactivity.
Example Sentences:
(1) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
(2) This derivative also allowed sensitive detection and measurement of indole-3-pyruvate in the picogram range using a gas chromatograph with an electron capture detector.
(3) In addition, it has excellent antibacterial activity against indole-positive Proteus strains against which conventional Cephalosporins are ineffective.
(4) These findings imply that smooth muscle replication in advanced plaques is indolent and raise the possibility of a role for proliferating leukocytes.
(5) Mitomycin C extravasation produces a painful indolent ulcer that does not have any tendency to heal.
(6) Among the indoles tested only 6-chloromelatonin, melatonin and N-acetylserotonin had significant affinities to the [125I]iodomelatonin binding site.
(7) Using thin layer chromatography on fluorescent silica gel plates, 5 indoles were identified and 6 unknown substances isolated from the pineal incubate and from both extracts.
(8) It was also found that the levels of s-dTK in the progressive stage were much higher than those in the indolent stage.
(9) Cyclobutadipyrimidines (pyrimidine dimers) undergo splitting that is photosensitized by indole derivatives.
(10) This series of compounds includes [R-(R*,R*)]-4-[[2-[[3-(1H-indol-3-yl)-2-methyl-1-oxo-2- [[(tricyclo[3.3.1.1] dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]- 4-oxobutanoic acid (CI-988, 1, Figure 1), the first rationally designed non-peptide antagonist of a neuropeptide receptor.
(11) Eight of the nine (88.9%) Proteus vulgaris isolates gave a positive spot indole test; one (11.1%) gave a negative result.
(12) 15 human tumour cell lines (lung, breast and colon) have been evaluated for their sensitivity to the quinone based anti-cancer drugs Mitomycin C, Porfiromycin, and EO9 (3-hydroxymethyl-5-aziridinyl-1-methyl-2-(IH-indole-4,7-dione)prop-beta- en-alpha-ol).
(13) The fluorogenic beta-D-Glucuronidase test, together with an Indol-capillary test for rapid identification of E. coli, were proved with 60 toxinogenic, 335 nontoxinogenic wild-type strains, and 87 other gram-negative isolates from food.
(14) Enzymatic production of L-tryptophan from DL-serine and indole by a coupled reaction of tryptophan synthase and amino acid racemase was studied.
(15) It inhibited some Enterobacter and indole-positive Proteus, but it was less active against these later species than was cefamandole, cefuroxime, or cefoxitin.
(16) An hydroxyl group in the 5 position of the indole nucleus, sterically unencumbered by hydroxyls in neighboing positions, is essential.
(17) We now report a second case with similar features of chronic recurrent indolent inflammatory skin lesions, nondiagnostic skin biopsies, and failure to respond to antibiotics.
(18) In this study, the roots of Tabernaemontana heyneana Wall were examined and the isolation and identification of additional indole alkaloids and some pharmacological properties of coronaridine are described.
(19) In an effort to understand the mechanism by which dietary indoles inhibit chemically initiated tumorigenesis in experimental animals, we have investigated the potency of 3-substituted and 1,3-disubstituted indoles on the induction of intestinal and hepatic cytochrome P-448-dependent monooxygenases in the rat.
(20) Low nanogram levels of tyrosine, norepinephrine, 5-hydroxyindole-3-acetic acid, tryptophan, serotonin and 6-hydroxymelatonin, and picogram levels of 5-hydroxytryptophan, 5-hydroxytryptophol, 5-methoxyindole-3-acetic acid, indole 3-acetic acid, 5-methoxytryptophol and melatonin were indicated in most of the samples.
Shirk
Definition:
(v. t.) To procure by petty fraud and trickery; to obtain by mean solicitation.
(v. t.) To avoid; to escape; to neglect; -- implying unfaithfulness or fraud; as, to shirk duty.
(v. i.) To live by shifts and fraud; to shark.
(v. i.) To evade an obligation; to avoid the performance of duty, as by running away.
(n.) One who lives by shifts and tricks; one who avoids the performance of duty or labor.
Example Sentences:
(1) Others have found more striking-power, or more simple poetry, but none an interpretation at once so full (in the sense of histrionic volume) and so consistently bringing all the aspects together, without any shirking or pruning away of what is inconvenient.
(2) A new report is just another excuse for those in power to shirk responsibility, to blame the people they have already degraded once and who cannot defend themselves.
(3) Time at home, alone, without chores, is still often felt as shirking responsibility.
(4) He’s taking a lot of stick at the moment – as everyone is – but it is a measure of him that he fronts it up every day and doesn’t shirk it.
(5) Shirk said one-party China – a country most still associate with little more than economic success and autocratic governance – saw a chance to rebrand itself as a benevolent great power acting in the common good.
(6) Neville has work ahead; the good news is that he will not shirk it.
(7) While some bosses shirk from defending their personal pay deals, Horta-Osório – whose 10-strong management team cashed in on £23m through the same bonus scheme – does not.
(8) Schreiber points out that some of the debates against the ERA were about "masculinity run amok": "Phyllis Schlafly said if we were are treated as equals, then men will shirk their responsibilities," she notes.
(9) Poon said Beijing was attempting to shift the focus on to how much medical attention Liu was receiving to shirk responsibility for its “cold-blooded” treatment of the democracy activist.
(10) They chased every ball, never shirked a tackle and, when they needed a centre-forward to show composure and experience, they had a 32-year-old from Stoke City, with silver flecks in his hair, who passed the test with distinction.
(11) Focusing on glorifying and eternalising the leaders and taking refuge in God and inserting them into hidden shirk [idolatry] through immortalising ephemeral, temporary personalities.
(12) At the same time, we will not shirk from vigorously defending our right and proper role to expose wrongdoing in the public interest."
(13) Are workers seen as a burden, a cost, people who would rather skive and shirk responsibilities, and who have to be supervised rigorously at all times?
(14) Jones said Australia was engaging with the UN with goodwill on how best to tackle the crisis, and not on how to shirk its international responsibilities.
(15) As Republicans we will not shirk our responsibility and we believe that it is now necessary for us to take this lead in bringing the agreement to its conclusion.
(16) "My desire to devolve authority has nothing to do with a wish to shirk responsibility.
(17) But he has never been one to shirk a challenge, choosing to serve in Vietnam so he could stay in the US after moving to New York in the 1960s.
(18) Some European partners are shirking from the task,” she said.
(19) However, human rights groups say Britain is shirking its legal responsibilities – fearful that the route could be seen as a “back door” to Britain – and coercing people into staying put while paying Cyprus to house and feed them.
(20) It’s not me shirking my responsibilities, I take internet security seriously, but I can’t always protect myself against an army of online fraud experts.