(a.) Not opportune; inconvenient; unseasonable; as, an inopportune occurrence, remark, etc.
Example Sentences:
(1) To prevent inopportune switching, HO transcription is restricted to a specific period in the haploid cell cycle, which is just after, and dependent on, the start of the mitotic cell cycle.
(2) The Vatican's spokesman Federico Lombardi insisted the rite took place in "a specific situation in which excluding the girls would have been inopportune in light of the simple aim of communicating a message of love to all".
(3) This makes demolition surgery, which is not often well accepted by the patient, inopportune.
(4) Inopportune coagulation of blood in vessels is prevented by defense mechanisms, in which plasma inhibitors play an important role.
(5) Other morphological radiographic appearances include a risk of misinterpretation and thus inopportune, inadequate or hazardous operative procedures.
(6) While Mark Wallinger's Ebbsfleet horse is eagerly awaited, Manchester's B of the Bang, its steel shards falling at disconcertingly inopportune moments, failed.
(7) An allergic reaction could occur at a most inopportune time.
(8) Indeed, Vidal claimed the terrorist attacks of 11 September 2001 occurred because the Bush administration was "incompetent" and Bush himself was "inactive and inopportune".
(9) All of which feels like an inopportune context for Keith Bristow, the director general of the new National Crime Agency , to request more police powers.
(10) Metastases of secreting tumors are verily more rare, nevertheless they are indubitably a major indication for embolisation, since good results are achieved concerning inopportune secretions and repeat embolisations possible are a super advantage.
(11) Due to a perfect confluence of inopportune circumstances, I have not been able to get the Talkboard standings from last week tallied up just yet.
(12) I lose count of the many times I have been reprimanded for an inopportune frown, eye-roll, or death stare (teachers found the latter particularly unnerving).
(13) The timing of the event, the last of three which took place during the week, was seen as inopportune, given the killing of a NYPD officer just days before .
(14) Because of this favorable outcome, all inopportune treatments must be avoided, and abstention is the best attitude.
(15) Nevertheless, the need to be away from school such as during an important examination, or from work, may be inopportune.
(16) The today usual diagnostic procedures in the postoperative follow up control are able to detect liver metastases in most cases only in an inopportune stage for therapy.
(17) "It may seem inopportune to be questioning growth while we are faced with daily news of the effects of recession, but allegiance to growth is the most dominant feature of an economic and political system that has led us to the brink of disaster.
(18) The remarks, which are unusual in a country where courts do not generally comment on cases before publishing their written reasoning, were reportedly described as "inopportune" by the chairman of the judges' governing body, the CSM.
(19) Therefore the separation of the healthy sibling takes frequently an inopportune course and should be adjusted by psychological psychiatric intervention within primary prevention.
(20) This tendency, apparently inopportune from the aspects of caries prevention, ensures, however, a permanent low F- level above the enamel surface.
Unfavorable
Definition:
(a.) Not favorable; not propitious; adverse; contrary; discouraging.
Example Sentences:
(1) Recently reported unfavorable clinical results (i.e., a high incidence of pain) have led to the discontinuation of one trial of porous polyethylene.
(2) By treatment of mice with anticancer agent CY or gamma ray irradiation, unfavorable side effects usually occurred to impair hematopoietic organs, causing bone marrow disorder.
(3) From the previously observed results of preferential interactions for salting-out salts with proteins, it was shown that the free energy of the protein is increased by addition of the salts and this unfavorable free energy is smaller for the proteins bound to the columns because of their smaller surface area exposed to solvent; i.e., the bound form of the proteins is thermodynamically more stable.
(4) Fifty percent of patients with the myelodysplastic syndrome, frequently following treatment by radiation or chemotherapy, have prognostically unfavorable deletions of the long arms of chromosomes 5 and 7, or trisomy 8, as have the 25% of patients with acute myeloblastic leukemia where remissions last 6-12 months, and where relapse cannot be prevented.
(5) Since liver metastases are the most common unfavorable outcome of colon cancer, ongoing trials using liver-directed treatment (perfusion, irradiation) should be followed with interest.
(6) Extracorporeal shockwave lithothripsy was very helpful in facilitating extraction of stones in unfavorable locations or located above the severe stricture.
(7) A positive deltaS compensates for an unfavorable positive deltaH so that the overall reaction is exergonic.
(8) The results show that conversion of Glu-208 to Gln greatly enhanced substrate binding, implying that Glu-208 interacts unfavorably with the substrate's ground state, preventing its optimal fit to the active site.
(9) Our data suggest that prostaglandin gel cervical ripening and induction of labor and delivery by 42 weeks' gestation may be the most appropriate management for patients with well-established gestational age and an unfavorable cervical examination.
(10) When patients with and without ST shift on Holter monitor ECG were compared, an unfavorable outcome was found in 48% versus 20% (p less than 0.005), multivessel disease in 76% versus 54% (p less than 0.01) and left main coronary stenosis in 18% versus 4% (p less than 0.05).
(11) Based on a preliminary trial that suggested that CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone), and PVB (cisplatinum, vinblastine, bleomycin), are at least partially non-cross-resistant, the Southwest Oncology Group treated patients with unfavorable histology, non-Hodgkin's lymphoma with CHOP and PVB.
(12) Myocardial transformation, along with its energy economizing effect, failed to compensate for unfavorable energetic consequences of structural dilatation and therefore the reduced ventricular efficiency is assumed to be another deleterious factor in the dilated failing heart.
(13) So far we believe that loss of hearing caused during these operations is mainly due to the unfavorable location of the cochlear blood supply through the meatus.
(14) Hypodiploidy is therefore an unfavorable karyotypic feature in childhood ALL.
(15) Hormone therapy was not indicated in these cases as it could lead to unfavorable results: decreased indices of definitive growth resulting from the formation of antibodies to the growth hormone.
(16) The course of gonarthrosis was unfavorable in that a majority of the cases became worse over the years and some also developed pain at rest.
(17) The favorable effects of up to 25% toasted soybean meal and 3% licorice root extract on the levels of the four enzymes, without unfavorable changes in clinical parameters, might account in part for the chemopreventive activities of these additives.
(18) The following signs in the preoperative radiographs were predictive of unfavorable outcome: small head fragment, comminution of the calcar femorale, and varus angulation of the head.
(19) When Rappaport's classification was used, division of unfavorable histologies into histiocytic and non-histiocytic groups provided only marginal significance in MVA.
(20) The outcome was unfavorable and the response to anticonvulsant drugs was poor.