(a.) Not tractable; not easily governed, managed, or directed; indisposed to be taught, disciplined, or tamed; violent; stubborn; obstinate; refractory; as, an intractable child.
Example Sentences:
(1) Four patients had previously been diverted and the other six were reconstructed because of intractable incontinence or deteriorating renal function.
(2) The medical records of 27 children admitted to the MINCEP Epilepsy Program for evaluation of intractable epilepsy but later shown to have nonepileptic events by EEG with simultaneous video monitoring were reviewed.
(3) The remaining eight patients who had surgery all had temporal lobectomies for intractable seizures; none had tumors.
(4) Phenacemide monotherapy controlled seizures in four children with intractable partial complex epilepsy.
(5) Intractable or progressing heart failure appeared to be a definite indication for emergency surgery, but medical therapy was recommended for mild to moderate heart failure.
(6) Results reveal a logical, understandable, and largely adaptive response to intractable seizures and offer little support for the concept of a dysfunctional or pathological interictal personality style.
(7) As a possible mechanism underlying the alterations of DRP, the functional consequences of atrophic changes of primary central afferent terminals are being discussed in terms of the close correlation between structure and function and the possible inferences of the electrophysiological reaction to the therapeutic application of Vinca alkaloids in the iontophoretic treatment of chronic intractable pain.
(8) One also had an associated valgus deformity and another had supination of the forefoot; all had intractable problems with footwear.
(9) Three years later he presented with intractable and ultimately fatal congestive heart failure.
(10) Since the introduction of computed tomography (CT) in 1974, 137 patients underwent cortical resection for intractable epilepsy.
(11) This study examined the relationship between long-term theophylline therapy and behavior problems in 14 asthmatic children that includes 5 intractable cases and 24 non-asthmatic children.
(12) The preresection and postresection intraoperative electrocorticograms of 76 consecutive patients undergoing resective surgery for intractable epilepsy were analyzed to see if location, configuration, and discharge rate of epileptiform activity correlated with type and location of pathology of the resected specimens and outcome in regard to seizure control.
(13) The two techniques of percutaneous cordotomy and pituitary injection of alcohol have been considered as methods applicable to the relief of intractable pain in inoperatable cancer.
(14) Captopril is an inhibitor of angiotensin I converting enzyme and is used for treating intractable chronic hypertension.
(15) Clomiphene citrate therapy was performed on 30 patients with idiopathic male infertility, who were intractable to non-hormonal therapy.
(16) Small bowel biopsies are not likely to be of assistance in determining the prognosis of this disorder and should not be used to determine therapy or to advise parents concerning the likely duration of intractable diarrhea of infancy.
(17) Two other patients had aortic root replacement, one at the age of 6.5 weeks due to intractable heart failure, and the other at the age of 3 months due to increasing gradient.
(18) A physical examination revealed intractable hiccups.
(19) In therapy, the provision of real-time visual feedback of tongue movement can be effective in the remediation of certain types of intractable speech problems.
(20) It is proposed that serum beta-2 microglobulin may be considered as a reliable parameter of the degree of severity of acute idiopathic anterior uveitis, as well as representing a useful tool for the evaluation of drug efficacy, especially in intractable cases.
Recalcitrant
Definition:
(a.) Kicking back; recalcitrating; hence, showing repugnance or opposition; refractory.
Example Sentences:
(1) Based on the principles of adaptational mutations and genetic exchange of catabolic activities, it becomes possible to select and engineer microorganisms that are suitable for the degradation of recalcitrant compounds.
(2) A prospective, randomized, double-blind, placebo-controlled multicentre study assessed the clinical efficacy and safety of pulsed electromagnetic limb ulcer therapy (PELUT) in the healing of recalcitrant, predominantly venous leg ulcers.
(3) We present a patient whose genital warts were recalcitrant to treatment.
(4) Isotretinoin (Accutane Capsules) is a synthetic vitamin A compound used for treatment of recalcitrant cystic acne.
(5) Such gene cassettes or operons can be transferred into suitable microbial hosts for extending and custom designing the pathways for rapid degradation of recalcitrant compounds.
(6) Of the 30 patients with warts, most of which were recalcitrant, 14 were cured and the remaining 16 showed marked improvement.
(7) This procedure is a simple and effective method for safe office treatment of patients with recalcitrant recurrent erosion.
(8) The thermal cycle sequencing procedures are advantageous because they allow fast and simple semiautomation of the sequencing reaction; make possible the direct DNA sequencing of PCR products, bacterial colonies and phage plaques; require only femtomoles of template DNA; eliminate the requirement of an independent primer annealing step; remove the requirement of denatured plasmids for sequencing double-stranded templates; and use a highly thermostable DNA polymerase for sequencing through potential recalcitrant secondary structure domains and large linear double-stranded DNA templates such as lambda derivatives.
(9) To study the human teratogenicity of this agent, we investigated 154 human pregnancies with fetal exposure to isotretinoin, a retinoid prescribed for severe recalcitrant cystic acne.
(10) The biosynthesis of prostaglandins (PG) in biopsies from 9 patients with recalcitrant psoriasis was studied before, during, and after treatment with 8-methoxy-psoralen and long-wave ultraviolet light (UVA).
(11) The Dec+ mutants had also acquired the capacity to metabolize other recalcitrant branched hydrocarbons such as 3,6-dimethyloctane and 2,6-dimethyldecane.
(12) Levamisole should be tried in recalcitrant chronic candidoses and bacterial infections not responding to specific antibiotic treatment.
(13) Thus, combination therapy is recommended for treatment of recalcitrant cases of bacterial endocarditis caused by N. mucosa.
(14) If the holding phase is sufficiently prolonged, a reduction in the number and complexity of operative procedures needed for recurrent and recalcitrant cases can be expected.
(15) Treatment of associated systemic disorders may improve the ulcers, but lesions may be recalcitrant and persist for months to years.
(16) Cyclosporine, an immunosuppressive drug, is effective in the treatment of recalcitrant psoriasis.
(17) In recalcitrant cases, however, entrapment of the first branch lateral plantar nerve should be suspected.
(18) These autonomous movements were otherwise recalcitrant to therapy and were felt to arise from neural generators intrinsic to the spinal cord.
(19) The effectiveness and tolerance of isotretinoin have been assessed in 72 cases (34 male and 38 female) suffering from papulo-pustular acne with nodulo-cystic component recalcitrant to traditional treatments.
(20) The government’s strategy is clearly based on a deep confidence that it has time, that it won’t be forced back to the polls by a recalcitrant Senate, that it will have years to reach a rapprochement with the angry states and that it will bring down two more budgets before it has to face the voters.