(a.) Not regular; not conforming to a law, method, or usage recognized as the general rule; not according to common form; not conformable to nature, to the rules of moral rectitude, or to established principles; not normal; unnatural; immethodical; unsymmetrical; erratic; no straight; not uniform; as, an irregular line; an irregular figure; an irregular verse; an irregular physician; an irregular proceeding; irregular motion; irregular conduct, etc. Cf. Regular.
(n.) One who is not regular; especially, a soldier not in regular service.
Example Sentences:
(1) Aggregation was more frequent in low-osmolal media: mainly rouleaux were formed in ioxaglate but irregular aggregates in non-ionic media.
(2) They were more irregularly curved and consisted of various substances.
(3) The results of the measurements permitted the identification of five main cytologic types, with regard to nuclear size, nuclear area dispersion and irregularity of nuclear profiles.
(4) A detailed stereochemical analysis of known protein structures has been made which shows that: (1) irregular regions of proteins consist of a limited number of standard structures formed by three, four of more residues; (2) an amino acid residue of a protein can adopt one of the six sterically allowed conformations designated here as alpha, alpha L, beta, gamma, delta, and epsilon.
(5) Endoscopy showed an irregular erosion of 4 by 2 cm, from which biopsies were taken.
(6) Aside from typical nuclear spheroids, irregularly shaped nuclei were frequently seen, associated with increased nuclear folds, transitional stages between nuclear folds and nuclear spheroids were also present.
(7) Although the level of ventilation is maintained constant during eating and drinking, the pattern of breathing becomes increasingly irregular.
(8) Numerous slender sarcotubules, originating from the A-band side terminal cisternae, extend obliquely or longitudinally and form oval or irregular shaped networks of various sizes in front of the A-band, then become continuous with the tiny mesh (fenestrated collar) in front of the H-band.
(9) What happened in the past was that if smugglers are sure that European boats are patrolling very close to the Libyan coast, then traffickers use this opportunity to advertise, and say to potential irregular migrants: ‘You will be sure to reach the European coast.
(10) In contrast, mean diameter of normal epicardial coronary artery tended to decrease and that of irregular epicardial coronary artery decreased significantly after intracoronary injection of acetylcholine.
(11) These findings are in agreement with the concept that irregular lesions represent ruptured atherosclerotic plaques and demonstrate that they usually originate from mildly occlusive smooth plaques.
(12) After 21 months, there appears to be no correlation between the amount of material adhering to the IUD and method complications (irregular and excessive bleeding) or method failure (pregnancy).
(13) The patient described in this report has the classic findings of Bardet-Biedl syndrome in conjunction with tibia vara and irregular physes of the lower extremities.
(14) After cessation her previously regular menstrual periods became very irregular and complete amenorrhea had lasted 4 months.
(15) Histochemical and electron-microscopic observations on a 30-month-old child with Hurler syndrome showed marked irregularities in chondrocyte orientation within the growth plate, along with disruption of the normal columnar architecture.
(16) The endocrine pattern and ovarian characteristics of 110 healthy adolescents with menstrual irregularities were investigated during the early follicular and premenstrual phases and were compared to those of 14 adolescents with regular menstrual cycles and 20 adults.
(17) Hypertrophy of the satellite cells with increase in the perineuronal intercellular spaces, often associated with irregular, scalloped nuclear and cell outlines, suggested that neuron shrinkage had occurred.
(18) Light microscopic examination of irregularly thickened white and black portions of abnormal scales demonstrated two distinctive populations of pigment-containing cells.
(19) In the second hypertrophied form [Type II], the endoplasmic reticulum is very prominent and occurs as a series of grossly dilated sacs of irregular shape.
(20) Disruption of the rhythmic activity of the inspiratory neurons and its replacement by a continuous and irregular discharge may lead to sustained contraction of inspiratory muscles and cessation of respiration.
Wrinkle
Definition:
(n.) A winkle.
(n.) A small ridge, prominence, or furrow formed by the shrinking or contraction of any smooth substance; a corrugation; a crease; a slight fold; as, wrinkle in the skin; a wrinkle in cloth.
(n.) hence, any roughness; unevenness.
(n.) A notion or fancy; a whim; as, to have a new wrinkle.
(v. t.) To contract into furrows and prominences; to make a wrinkle or wrinkles in; to corrugate; as, wrinkle the skin or the brow.
(v. t.) Hence, to make rough or uneven in any way.
(v. i.) To shrink into furrows and ridges.
Example Sentences:
(1) Transmission electron microscopy demonstrated that these blebs were devoid of organelles and microvilli; scanning electron microscopy revealed that the blebs were highly wrinkled and more numerous than were the projections observed in tissue from animals treated with testosterone alone, or in tissue from unoperated controls.
(2) However, patients can be taught how to retard the onset of wrinkles by avoiding unprotected sun exposure, unnecessary facial movements, and certain sleeping positions.
(3) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(4) In fact, in some patients the lower-lid wrinkling appears far worse after fat removal.
(5) Substratum wrinkling was indicative of tension development and quantitated as percent of cells contracted.
(6) SMC also displayed several structurally detectable interactions with the fibrin substratum, such as organization of the gel by means of extension of numerous filamentous processes and contraction and wrinkling of the gel.
(7) A recipient cornea gradually developed wrinkling and opacification in Bowman's layer following an uneventful myopic epikeratoplasty.
(8) "But then a customer pointed out that our carpet was smoking and a chair was beginning to wrinkle in the heat, caused by the concentrated sun coming through the window."
(9) More than once, she replies to a question by wrinkling her nose and saying: “It’s all in the book.” Tempest can’t quite see why the breadth of her output – songs, poems, plays, a novel – is notable, because it’s all about writing and performance.
(10) Some intercalated sheaths had a wrinkled irregular configuration and some lacked a light-microscopically distinct myelin layer.
(11) Adhesions to the Gore-SM occurred at wrinkles in or at the edges of the membrane.
(12) During the course of the irradiation the animals develop permanent wrinkles on the exposed dorsal surface, which can be recorded in plastic impressions.
(13) The deflecting wrinkle is a well-known character state of the lower m2 and M1 of the human dentition, but there is little information regarding its presence in great apes.
(14) An algorithm is used to transform the number of wrinkles, recorded just before and 2.5 and 6 hr after the injection, into the intensity of the oedematous reaction.
(15) Fine wrinkling, coarse wrinkling, sallowness, looseness, and hyperpigmentation were significantly improved with tretinoin therapy.
(16) Kaeng Khoi virus was recovered from bedbugs (Stricticimex parvus and Cimex insuetus) and from suckling wrinkle-lipped bats (Tadarida plicata) collected in central Thailand.
(17) Hacked Off, which campaigns on behalf of victims of press intrusion for tighter press regulation, said this would help the government smooth out the wrinkles in the relevant clause added to the crime and courts bill, which attempts to define which publishers should be in or outside the regulator's remit.
(18) The percentage of cells showing a decrease of wrinkles was significantly higher (P less than 0.05 at 5 min and P less than 0.001 at 10 min) during the ANP-treated period than during the control period.
(19) Most dogs give a series of increasingly serious warning signs before they lose their tempers: lick their lips, blink, turn their heads away, curl their lip, lower their ears, wrinkle their foreheads, and if the dog that's annoying them doesn't get the message, they may growl or bare their teeth, and if that's still not enough it will be head and chest forward, muscles flexed, and bang, you've had it.
(20) Other specimens showed wrinkling of the outer layer that was seen later to peel off.