(1) This enhancer sequence is not strictly cell-type specific since it functions in cell lines of both placental (JEG-3) and pituitary (18-54,SF) origin.
(2) VIP maximally increased the transient expression of CRE alpha CAT and the expression of endogenous hCG-alpha mRNA in JEG-3 cells by 4- and 9-fold, respectively.
(3) This result may be explained by the observation that the JAr cells lacked any detectable glucocorticoid receptor and the receptor levels in cytosol prepared from JEG and BeWo cells were 12% and 2%, respectively, of those measured in HeLa cytosol.
(4) The HLA-6.0 or HLA-E genes may encode the lower molecular mass component on Jeg-3 cells, because these genes express molecules of about 38 kDa and 41 kDa, respectively, when transfected to appropriate host cells.
(5) In order to determine whether RA stimulates the hCG secretion by other trophoblastic cell lines, we evaluated the effect of RA on hCG, hCG-alpha subunit (hCG-alpha), and progesterone secretion in three choriocarcinoma cell lines: JEG-3, JAR, and BeWo.
(6) Reporter genes containing either the intact 1.5 kilobase of 5'-flanking sequence from the HCG alpha gene, or just the 36-bp tandem repeat cAMP response element, when coupled to an enhancerless promoter, both exhibit a vigorous cAMP stimulation of expression but no response to phorbol ester in JEG-3 cells.
(7) We demonstrate the molecular peculiarities of these modified smooth muscle cells using monoclonal antibodies produced against a benign human JEG-cell tumour.
(8) The transcriptional activities of P1 + P2 in their natural tandem orientation were additive in rat keratinocytes and human JEG choriocarcinoma cells.
(9) Using DNase I protection analyses and gel-mobility shift assays, we examined in vitro the domains in the human alpha-gene 5'-flanking sequence that bind nuclear proteins extracted from JEG-3 choriocarcinoma cells.
(10) The effect of JEG-3 choriocarcinoma supernatant on human natural killer cell and lymphokine-activated killer cell activity was investigated.
(11) Similar observations have been made in JeG-3 cells and Chinese hamster ovary cells stably transfected with human apoE cDNA constructs.
(12) In human choriocarcinoma JEG-3 and monkey COS-1 cells, the cytosolic thyroid hormone binding protein is a monomer of the tetrameric pyruvate kinase, subtype M2, which does not bind T3.
(13) In this study the 5'-flanking sequence of the CG beta gene was fused to a sensitive luciferase (LUC) reporter gene, allowing delineation of a CG beta CRE in transient expression assays performed in JEG-3 choriocarcinoma cells.
(14) JEG-3 choriocarcinoma cells demonstrate c-myc transcript levels that are greater than those of nonmalignant trophoblastic tissue at any stage of gestation.
(15) No significant expression of any of these ANG-GH fusion genes over the promoterless pOGH was observed in JEG-3 cells.
(16) Results of these studies suggest that there is some degree of tissue specificity of FN gene expression and reveal that cAMP induction is mediated, in part, by the same element (CRE) in both HT-1080 and JEG-3 cells.
(17) Epidermal growth factor (EGF) binds to JEG-3 cells, a tissue culture line of human choriocarcinoma.
(18) In JEG-3 choriocarcinoma cells the MMTV promoter is transcribed inefficiently, even after transfection of the receptor cDNA and treatment with glucocorticoids or progestins.
(19) A similar increase in Class I antigens is also found in JEG-3 choriocarcinoma cells after treatment with IFN-gamma.
(20) Deletion of the FN promoter from positions -510 to -56 resulted in an ~30-fold decrease in promoter activity when this construction was transfected into HT-1080 cells, and similar results were observed in NIH 3T3 cells; however, less than a 2-fold effect was observed in JEG-3 cells.
Leg
Definition:
(v. t.) To run.
(v. t.) To use as a leg, with it as object
(v. t.) To bow.
(n.) A limb or member of an animal used for supporting the body, and in running, climbing, and swimming; esp., that part of the limb between the knee and foot.
(n.) That which resembles a leg in form or use; especially, any long and slender support on which any object rests; as, the leg of a table; the leg of a pair of compasses or dividers.
(n.) The part of any article of clothing which covers the leg; as, the leg of a stocking or of a pair of trousers.
(n.) A bow, esp. in the phrase to make a leg; probably from drawing the leg backward in bowing.
(n.) A disreputable sporting character; a blackleg.
(n.) The course and distance made by a vessel on one tack or between tacks.
(n.) An extension of the boiler downward, in the form of a narrow space between vertical plates, sometimes nearly surrounding the furnace and ash pit, and serving to support the boiler; -- called also water leg.
(n.) The case containing the lower part of the belt which carries the buckets.
(n.) A fielder whose position is on the outside, a little in rear of the batter.
Example Sentences:
(1) Calcium alginate dressings have been used in the treatment of pressure ulcers and leg ulcers.
(2) Muscle weakness and atrophy were most marked in the distal parts of the legs, especially in the gastrocnemius and soleus muscles, and then spread to the thighs and gluteal muscles.
(3) The adaptive filter processor was tested for retrospective identification of artifacts in 20 male volunteers who performed the following specific movements between epochs of quiet, supine breathing: raising arms and legs (slowly, quickly, once, and several times), sitting up, breathing deeply and rapidly, and rolling from a supine to a lateral decubitus position.
(4) Blood flow was measured in leg and torso skin of conscious or anesthetized sheep by using 15-micron radioactive microspheres (Qm) and the 133Xe washout method (QXe).
(5) A leg ulcer in a 52-year-old renal transplant patient yielded foamy histiocytes containing acid-fast bacilli subsequently identified as a Runyon group III Mycobacterium.
(6) An anatomic study of the peroneal artery and vein and their branches was carried out on 80 adult cadaver legs.
(7) In contrast sham-hemodialysis in group CA and group PS, respectively, did not result in significant increases in amino acid efflux from the leg implying that the protein catabolic effect of blood membrane contact depends on the chemical properties of dialysis membranes.
(8) The ulcers on seven of ten legs (70%) treated with Unna's boots and on 10 of 14 legs (71%) treated with elastic support stocking healed.
(9) These reflexes can function to limit forces applied to a leg and provide compensatory adjustments in other legs.
(10) A second group was chronically implanted without electrical stimulation in one leg and implanted with cyclical electrical stimulation applied through the electrode in the other leg.
(11) Attention is paid to the set of problems connected with the nonthrombotic insufficiency of the conducting veins of the leg.
(12) In the case of unilateral blockade at the groin or pelvis, the grafts connect the lymphatics of the thigh of the affected leg with lymphatics in the contralateral healthy groin.
(13) This, however will not result in normal lower leg bones, as can be concluded from the fact that spontaneous fractures have occurred partly even in the locomotor apparatus after the pseudarthroses had healed.
(14) It’s gender, age, disability, sexual orientation, social background, and – most important of all, as far as I’m concerned – diversity of thought.” Diversity needs action beyond the Oscars | Letters Read more He may have provided the Richard Littlejohn wishlist from hell – you know the one, about the one-legged black lesbian in a hijab favoured by the politically correct – but as a Hollywood A-lister, the joke’s no longer on him.
(15) According to perimeter of leg, 13% of these girl students might he considered affected of second degree malnutrition, this situation prevailed from 13 to 18 years of age, but was not true in the 12--year--old group.
(16) Martin O’Neill spoke of his satisfaction at the Republic of Ireland’s score draw in the first leg of their Euro 2016 play-off against Bosnia-Herzegovina – and of his relief that the match was not abandoned despite the dense fog that descended in the second half and threatened to turn the game into a farce.
(17) Adjunctive usage of elastic stockings and intermittent compression pneumatic boots in the perioperative period was helpful in controlling leg swelling and promoting wound healing.
(18) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(19) Significant differences were found for the clinical scores for legs with and without previous DVT, which shows that the method is of value despite a not inconsiderable interobserver variation.
(20) The devices worked as well on postphlebitic legs as on normal ones.