(n.) An instrument by means of which the bolt of a lock is shot or drawn; usually, a removable metal instrument fitted to the mechanism of a particular lock and operated by turning in its place.
(n.) An instrument which is turned like a key in fastening or adjusting any mechanism; as, a watch key; a bed key, etc.
(n.) That part of an instrument or machine which serves as the means of operating it; as, a telegraph key; the keys of a pianoforte, or of a typewriter.
(n.) A position or condition which affords entrance, control, pr possession, etc.; as, the key of a line of defense; the key of a country; the key of a political situation. Hence, that which serves to unlock, open, discover, or solve something unknown or difficult; as, the key to a riddle; the key to a problem.
(n.) That part of a mechanism which serves to lock up, make fast, or adjust to position.
(n.) A piece of wood used as a wedge.
(n.) The last board of a floor when laid down.
(n.) A keystone.
(n.) That part of the plastering which is forced through between the laths and holds the rest in place.
(n.) A wedge to unite two or more pieces, or adjust their relative position; a cotter; a forelock.
(n.) A bar, pin or wedge, to secure a crank, pulley, coupling, etc., upon a shaft, and prevent relative turning; sometimes holding by friction alone, but more frequently by its resistance to shearing, being usually embedded partly in the shaft and partly in the crank, pulley, etc.
(n.) An indehiscent, one-seeded fruit furnished with a wing, as the fruit of the ash and maple; a samara; -- called also key fruit.
(n.) A family of tones whose regular members are called diatonic tones, and named key tone (or tonic) or one (or eight), mediant or three, dominant or five, subdominant or four, submediant or six, supertonic or two, and subtonic or seven. Chromatic tones are temporary members of a key, under such names as " sharp four," "flat seven," etc. Scales and tunes of every variety are made from the tones of a key.
(n.) The fundamental tone of a movement to which its modulations are referred, and with which it generally begins and ends; keynote.
(n.) Fig: The general pitch or tone of a sentence or utterance.
(v. t.) To fasten or secure firmly; to fasten or tighten with keys or wedges.
Example Sentences:
(1) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(2) A key way of regaining public trust will be reforming the system of remuneration as agreed by the G20.
(3) Instead, the White House opted for a low-key approach, publishing a blogpost profiling Trinace Edwards, a brain-tumour victim who recently discovered she was eligible for Medicaid coverage.
(4) The presence of a few key residues in the amino-terminal alpha-helix of each ligand is sufficient to confer specificity to the interaction.
(5) The key warning from the Fed chair A summary of Bernanke's hearing Earlier... MPs in London quizzed the Bank of England on Libor.
(6) "Seller reports are key to identifying bad buyers and ridding them from our marketplace," says eBay.
(7) It is suggested that the low-density lipoprotein receptors in human fetal liver may play a key role in the regulation of the serum cholesterol levels during gestation.
(8) A key component of a career program should be recognition of a nurse's needs and the program should be evaluated to determine if these needs are met.
(9) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
(10) Meanwhile, Hunt has been accused of backtracking on a key recommendation in the official report into Mid Staffs.
(11) The safe motherhood initiative demands an intersectoral, collaborative approach to gynecology, family planning, and child health in which midwifery is the key element.
(12) Acetylcholinesterase is a key enzyme in cholinergic neurotransmission for hydrolyzing acetylcholine and has been shown to possess arylacylamidase activity in addition to esterase activity.
(13) If Lagarde had been placed under formal investigation in the Tapie case, it would have risked weakening her position and further embarrassing both the IMF and France by heaping more judicial worries on a key figure on the international stage.
(14) Four goals, four assists, and constant movement have been a key part of the team’s success.
(15) Mechanosensitive ion channels may play a key role in transducing vascular smooth muscle (VSM) stretch into active force development.
(16) But Abaaoud, the man thought to be a key planner for the group behind the Paris attacks, boasted to a niece that he had brought around 90 militants back to Europe with him.
(17) Key therapeutic questions are whether beta-lactams can safely replace aminoglycosides for the treatment of gram-negative pneumonia, and whether monotherapy or aminoglycoside and beta-lactam combination antibiotic treatment is superior.
(18) Teaching procedures then establish and build these key components to fluency.
(19) Doubts about Hinkley Point have deepened after a detailed report by HSBC’s energy analysts described eight key challenges to the project, which will be built by the state-backed French firm EDF and be part-financed by investment from China .
(20) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
Mark
Definition:
(n.) A license of reprisals. See Marque.
(n.) An old weight and coin. See Marc.
(n.) The unit of monetary account of the German Empire, equal to 23.8 cents of United States money; the equivalent of one hundred pfennigs. Also, a silver coin of this value.
(n.) A visible sign or impression made or left upon anything; esp., a line, point, stamp, figure, or the like, drawn or impressed, so as to attract the attention and convey some information or intimation; a token; a trace.
(n.) A character or device put on an article of merchandise by the maker to show by whom it was made; a trade-mark.
(n.) A character (usually a cross) made as a substitute for a signature by one who can not write.
(n.) A fixed object serving for guidance, as of a ship, a traveler, a surveyor, etc.; as, a seamark, a landmark.
(n.) A trace, dot, line, imprint, or discoloration, although not regarded as a token or sign; a scratch, scar, stain, etc.; as, this pencil makes a fine mark.
(n.) An evidence of presence, agency, or influence; a significative token; a symptom; a trace; specifically, a permanent impression of one's activity or character.
(n.) That toward which a missile is directed; a thing aimed at; what one seeks to hit or reach.
(n.) Attention, regard, or respect.
(n.) Limit or standard of action or fact; as, to be within the mark; to come up to the mark.
(n.) Badge or sign of honor, rank, or official station.
(n.) Preeminence; high position; as, particians of mark; a fellow of no mark.
(n.) A characteristic or essential attribute; a differential.
(n.) A number or other character used in registring; as, examination marks; a mark for tardiness.
(n.) Image; likeness; hence, those formed in one's image; children; descendants.
(n.) One of the bits of leather or colored bunting which are placed upon a sounding line at intervals of from two to five fathoms. The unmarked fathoms are called "deeps."
(v. t.) To put a mark upon; to affix a significant mark to; to make recognizable by a mark; as, to mark a box or bale of merchandise; to mark clothing.
(v. t.) To be a mark upon; to designate; to indicate; -- used literally and figuratively; as, this monument marks the spot where Wolfe died; his courage and energy marked him for a leader.
(v. t.) To leave a trace, scratch, scar, or other mark, upon, or any evidence of action; as, a pencil marks paper; his hobnails marked the floor.
(v. t.) To keep account of; to enumerate and register; as, to mark the points in a game of billiards or cards.
(v. t.) To notice or observe; to give attention to; to take note of; to remark; to heed; to regard.
(v. i.) To take particular notice; to observe critically; to note; to remark.
Example Sentences:
(1) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(2) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(3) Following in vitro C activation in NHS by delta IgG, the 40 KD C4d component increased markedly.
(4) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
(5) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(6) Increased dietary protein intake led to increased MDA per nephron, increased urinary excretion of MDA, and increased MDA per milligram protein in subtotally nephrectomized animals, and markedly increased the glutathione redox ratio.
(7) Cyclic AMP stimulated phosphorylation by [gamma-32P]ATP of two proteins of apparent Mr = 20,000 and 7,000 that were concentrated in sarcoplasmic reticulum, but the stimulation was markedly dependent on the presence of added soluble cyclic AMP-dependent protein kinase.
(8) Surprisingly, the clonal elimination of V beta 6+ cells is preceded by marked expansion of these cells.
(9) Muscle weakness and atrophy were most marked in the distal parts of the legs, especially in the gastrocnemius and soleus muscles, and then spread to the thighs and gluteal muscles.
(10) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(11) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
(12) Marked enhancement of IFN-gamma production by T cells was seen in the presence of as little as 0.3% thymic DC.
(13) This effect was more marked in breast cancer patients which may explain our earlier finding that women with upper body fat localization are at increased risk for developing breast cancer.
(14) Completeness of isolation of the coronary and systemic circulations was shown by the marked difference in appearance times between the reflex hypotensive responses from catecholamine injections into the isolated coronary circulation and the direct hypertensive response from a similar injection when the circulations were connected as well as by the marked difference between the pressure pulses recorded simultaneously on both sides of the aortic balloon separating the two circulations.4.
(15) A marked overlap of input from the two eyes is an unusual feature for a diprotodont marsupial and has previously been seen only in the feathertail glider.
(16) The erythrocyte sedimentation rate is almost always markedly elevated.
(18) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
(19) Her muscle weakness and hyperCKemia markedly improved by corticosteroid therapy, suggesting that the diagnosis was compatible with polymyositis (PM).
(20) The introduction of intravenous, high-dose thrombolytic therapy during a brief period has markedly reduced mortality of patients with acute myocardial infarction.