(n.) A hard protuberance; a hard swelling or rising; a bunch; a lump; as, a knob in the flesh, or on a bone.
(n.) A knoblike ornament or handle; as, the knob of a lock, door, or drawer.
(n.) A rounded hill or mountain; as, the Pilot Knob.
(n.) See Knop.
(v. i.) To grow into knobs or bunches; to become knobbed.
Example Sentences:
(1) The narrow intercellular ridge is smooth, whereas the epithelial cells have small cytoplasmic knobs between the cilia.
(2) The histochemical study of the LDH in the Trout embryo during the early organogenesis shows a specific localization in notochord cells, in mesodermic cells of the terminal knob and in some prosencephalic neuroblasts.
(3) Motor axons possessed elongate, irregularly shaped boutons en passant and morphologically variable boutons terminaux; the latter included huge endings with knobbed projectiles arising from thick collaterals, or smaller, round boutons from thin collaterals.
(4) Men might not have frills and furbelows as women traditionally do, but they’ve got spurious function: knobs on their watches or extra pockets on their jackets that are just as decorative as anything women wear.” 6.
(5) As with established cell lines, formation of zeiotic knobs at the isolated Type 1 cell surface appeared closely related to microfilamentous nets located beneath the plasmalemma.
(6) The isolated cells have an ovoid soma, a dendrite of variable length which terminates in a cilia-bearing knob and an axon, also of variable length.
(7) In addition, some reacted with either knob protrusions or caveolae of the host erythrocyte membrane; one reacted with a parasite-derived antigen present in the erythrocyte cytoplasm.
(8) "It might be that you think it's just a knob on the front panel, but maybe installing it requires you disassemble the front panel, and actually you need a mechanic to come and fit it," argues Rowley.
(9) wt from 80 to 95 kd in different knob-producing isolates of P. falciparum and is absent in knobless variants.
(10) To investigate environmental influences on the development of the olfactory epithelium, semi-thin sections were taken from the nasal septum of newborn and 30-day-old rabbits; the epithelial thickness and the number of olfactory knobs, supporting cells, dark basal cells, and receptor cells were compared.
(11) The spores of Rif-18 are pleomorphic and frequently exhibit terminal knobs.
(12) To investigate the involvement of actin filaments in concanavalin A (Con A)-induced cap formation and cytochalasin B (CB)-induced zeiotic knob migration, the distribution of F-actin was studied in Con A-treated and CB-treated Ehrlich ascites tumor cells (EATC) by fluorescence microscopy using heavy meromyosin conjugated with a fluorescent dye, N-(7-dimethylamino-4-methylcoumarinyl) maleimide, (DACM-HMM).
(13) 205 subjects each chose a "most pleasant" sound delivered through an earphone by turning the control knob on a continuously variable audio oscillator.
(14) Knobs which appear on the membrane of the infected erythrocytes adhere to the endothelium, causing the obstruction of cerebral microvessels.
(15) Cytoadherence of infected erythrocytes in vivo is associated with the presence of knobs on the erythrocyte surface, but we and others have shown recently that cytoadherence to C32 melanoma cells may occur in vitro in the absence of knobs.
(16) Systemic administration of the anti-inflammatory agent indomethacin blocked vascular leakage due to endothelial gap formation but had little or no effect on trophoblast knob penetration of vessels.
(17) After crossectomy which remains the most important stage, a short stripping is performed in an upward direction, substituting a packing for the olive shaped knob normally used.
(18) Under scanning electron microscopy, O. viverrini eggs looked like musk-melon skin; they had prominent shoulders and long knobs.
(19) Six culture-adapted knob-positive Plasmodium falciparum parasites, four of which were nonbinding in an in vitro cytoadherence assay, were tested for the presence of the knob-associated histidine-rich protein PfHRP1.
(20) Instead, there were free and spiral nerve terminals in the interstitium, and epilemmal knob-like or bouton-like endings surrounding non-encapsulated muscle fibers.
Thickening
Definition:
(p. pr. & vb. n.) of Thicken
(n.) Something put into a liquid or mass to make it thicker.
Example Sentences:
(1) These immunocytochemical studies clearly demonstrated that cells encountered within the fibrous intimal thickening in the vein graft were inevitably smooth muscle cell in origin.
(2) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(3) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(4) The wall of the yolk sac thickens as a result of this infolding and the densely packed capillaries.
(5) Strong correlations were found also between postsystolic shortening and thickening measured immediately before reperfusion and systolic shortening and thickening measured after recovery at 2-3 weeks (r = 0.73, n = 28; p less than 0.001 for shortening; r = 0.79, n = 12; p less than 0.01 for thickening).
(6) During development of the tubular cysts the cystic BM appeared thickened and multilayered, with numerous matrix vesicles.
(7) Fibrinogen was scattered in the intercellular spaces, and located in the inner layer or edges of the thickened intima of the bifurcation with increasing plaque formation.
(8) In castrates, the prostatic stroma became thickened, with a large increase in fibrous material between and surrounding each acinus, although smooth muscle cells retained their normal cytology.
(9) Confirmatory tests of sinus disease are transillumination (useful in adolescents if interpretation is confined to the extremes--normal or absent); radiographic findings of opacification, mucous membrane thickening, or an air-fluid level; and sinus aspiration (indicated for severe pain, clinical failures, or complicated disease).
(10) (1986) described the connective tissue thickening and named it the mandibulo-stylohyoid ligament because of its arrangement and attachments.
(11) 6 patients had thickened pericardium, and 3 had constrictive features.
(12) In abnormal arteries such as small vessels present in inflammatory tissue, the IEL was frequently discontinuous and associated with intimal thickening.
(13) The calculations revealed that local hypoxia and lipoprotein accumulation may occur at the ridges, leading to subsequent intimal thickening and ridge growth.
(14) Light microscopy of the kidneys revealed mesangial expansion, glomerular capillary wall thickening, and lumenal thrombosis.
(15) This case suggests that myocardial inflammation and edema may cause thickening of the ventricular wall during the course of acute myocarditis.
(16) Light microscopic examination of irregularly thickened white and black portions of abnormal scales demonstrated two distinctive populations of pigment-containing cells.
(17) Adenosine triphosphatase activity in some synaptic vesicles and mitochondria, on pre- and postsynaptic membranes, as well as in the postsynaptic thickening was established.
(18) At the former site the membrane overlying the bud showed an electron opaque thickening which imparted to the mature particle an asymmetrical appearance.
(19) Interalveolar septa were hypercellular and multifocally thickened.
(20) Thickening of the gallbladder wall, a subserosal "halo" of edema, pericholecystic abscess, and marked gallbladder distention were consistent findings in AAC.