(n.) A small opening; a small pit or depression; a small blank space; a gap or vacancy; a hiatus.
(n.) A small opening; a small depression or cavity; a space, as a vacant space between the cells of plants, or one of the spaces left among the tissues of the lower animals, which serve in place of vessels for the circulation of the body fluids, or the cavity or sac, usually of very small size, in a mucous membrane.
Example Sentences:
(1) Casts of lacunae and canaliculi along with the underlying matrix could be visualized in these preparations.
(2) This kind of distribution of microfilaments was always associated with resorption lacunae, and F-actin, vinculin, and talin zones correspond roughly to the edge of lacunae.
(3) As lacunae develop, both syncytial and cytotrophoblast are exposed to maternal blood.
(4) A cartilage is regarded as 'cell-rich' if its cells or their lacunae occupy more than half of the tissue volume.
(5) Intravenous urography reveals the presence of a persistent lacuna in a calix or of the pelvis, radiologic evidence of the abnormal papilla.
(6) Under the scanning electron microscope, the clear dentine tubules in the resorption lacuna, the shallow, unclear resorption lacuna with deposition of the hard tissue and the various steps between them were observed.
(7) Localised tumour forms present either in the form of large polycyclic lacunae, sometimes invaginated or as vast ulcerations with irregular nodular margin, or as due to parietal infiltration and exoluminal development of the tumour mass and neighbouring adenopathy.
(8) The resorbant organ, rich in odontoclasts, cementoblasts, fibroblasts, and macrophages, formed prominent resorption lacunae in root dentin.
(9) Signs of osteolysis, such as enlarged osteocyte lacunae surrounded by a metachromatic zone in toluidine blue stained sections, and confluence of osteocyte lacunae in microradiographs, were compared with the fluorochrome labelling pattern.
(10) These had networks which formed the floor of each stomata and the roof of each lacunae.
(11) Besides greater detailization of the prevailing diameters of the pores, the method of poremetry allows the information to be obtained concerning the distribution of not only sizes of central canals of osteons but also smaller pores characterizing the system of lacunae of osteocytes and canals connecting them.
(12) Osteocyte viability within the femoral head was assessed by counting empty osteocyte lacunae in five random high-power fields of hematoxylin- and eosin-stained sections.
(13) Lipohyalinosis, initially referred to as the underlying pathologic vascular lesion specific for lacunae, is found most commonly in a subset of patients with severe hypertension associated with multilacunar dementia.
(14) These areas were characterized by a matrix of amorphous blue ground substance with lacunae that contained enlarged and slightly atypical cells.
(15) The condition was diagnosed by biopsy of a cranial bone lacuna.
(16) When ascorbic acid is added to the hormone-supplemented medium, differentiating chondrocytes organize their matrix leading to a cartilage-like structure with hypertrophic chondrocytes embedded in lacunae.
(17) The occlusion of arterioles underneath the site suggests that circulation through the lacunae at this stage is indirect.
(18) The second most common cause of dementia, cerebrovascular disease, produces dementia only when there is destruction of brain tissue, as in individuals who have multiple strokes or who have hypertensive vascular disease leading to multiple lacunae.
(19) Macrophages and giant cells did not form pits or resorption lacunae on the bone substrates as osteoclasts did.
(20) These MNC express an osteoclast phenotype and form resorption lacunae on calcified matrices.
Shortcoming
Definition:
(n.) The act of falling, or coming short
(n.) The failure of a crop, or the like.
(n.) Neglect of, or failure in, performance of duty.
Example Sentences:
(1) This paper provides an overview of the theory, indicating its contributions--such as a basis for individual psychotherapy of severe disorders and a more effective understanding of countertransference--and its shortcomings--such as lack of an explanation for the effects of physical and cognitive factors on object relatedness.
(2) The author describes changes in the activities of the psychiatric institutions, analyzes the causes of the changes and shortcomings in the work of the in- and outpatient services.
(3) Attention is drawn to the shortcomings in our current knowledge of the scale of turnover of the sulphur cycle and of our understanding of the microorganisms involved in specialized environments.
(4) False-positive results due to methodological shortcomings can be avoided by applying both methods in succession.
(5) This validity coefficient turned out to be so high (r = 0.967) that it does not seem necessary to adopt a more sophisticated method, despite a few demonstrable shortcomings of the one in use.
(6) Diagnostic information derived from PA catheters should be related to the clinical condition and shortcomings and pitfalls of data clearly understood.
(7) The reasons for the shortcomings of the DRG system in predicting utilization of services are discussed, and areas for future research are suggested.
(8) A system of ordering the relative toxicity of these (and other) drugs is proffered using the exposure-case fatality rate (ECFR) as a crude measure of clinical toxicity (while delineating its shortcomings).
(9) The crash exposed shortcomings in standards in regulators almost as bad as in banks.” The Treasury denied it was involved in the review being dropped, although it has been involved in changing some of the tougher rules being used to clamp down on bankers.
(10) Saxo Bank said: "This highlights one of the shortcomings of the status quo in the European periphery: that Portugal (and other peripheral countries) exiting the programmes at this stage appears rather premature.
(11) Dean's system, however, has several shortcomings, principally its inability to measure fluorosis in different tooth surfaces.
(12) The shortcomings of existing statistical software for personal computers and trends of their improvements are analyzed.
(13) At the same time, application of DNA rearrangement to the evaluation of tissue specimens also has certain shortcomings and limitations, some of which may be overcome by current research methods or advances expected in the near future.
(14) Mohammed Siddique, a 60-year-old imam, and his 24-year-old son, Mohammed Waqar, punished the boy for perceived shortcomings during religious lessons at the Sparkbrook Islamic centre, attached to the Jamia mosque, in Birmingham.
(15) Existing bedside emergency resuscitation carts all have certain shortcomings, which interfere with the rapid, efficient care of the hospitalized patient in a catastrophic episode.
(16) The nature and shortcomings of relevant studies are described, the need for scientifically based research championed, and a differential approach to directive treatment of borderline children advocated.
(17) David Bennett, A&L's group chief executive, said: "I apologise sincerely for our shortcomings.
(18) He is undaunted by their scale, and realistic about their shortcomings.
(19) Jeb Bush should stop trying to defend his brother and focus on his own shortcomings and how to fix them,” he tweeted .
(20) After expressing frustration with Stoke City's style of play, the dreadful standard of the game and the lack of width available on a pitch narrowed to exploit Rory Delap's throw-ins, Tony Mowbray finally realised that a sixth defeat in seven matches might also owe something to West Bromwich Albion's shortcomings.