(3d pers. sing. pres.) of Last, to endure, contracted from lasteth.
(a.) Being after all the others, similarly classed or considered, in time, place, or order of succession; following all the rest; final; hindmost; farthest; as, the last year of a century; the last man in a line of soldiers; the last page in a book; his last chance.
(a.) Next before the present; as, I saw him last week.
(a.) Supreme; highest in degree; utmost.
(a.) Lowest in rank or degree; as, the last prize.
(a.) Farthest of all from a given quality, character, or condition; most unlikely; having least fitness; as, he is the last person to be accused of theft.
(a.) At a time or on an occasion which is the latest of all those spoken of or which have occurred; the last time; as, I saw him last in New York.
(a.) In conclusion; finally.
(a.) At a time next preceding the present time.
(v. i.) To continue in time; to endure; to remain in existence.
(v. i.) To endure use, or continue in existence, without impairment or exhaustion; as, this cloth lasts better than that; the fuel will last through the winter.
(v. i.) A wooden block shaped like the human foot, on which boots and shoes are formed.
(v. t.) To shape with a last; to fasten or fit to a last; to place smoothly on a last; as, to last a boot.
(n.) A load; a heavy burden; hence, a certain weight or measure, generally estimated at 4,000 lbs., but varying for different articles and in different countries. In England, a last of codfish, white herrings, meal, or ashes, is twelve barrels; a last of corn, ten quarters, or eighty bushels, in some parts of England, twenty-one quarters; of gunpowder, twenty-four barrels, each containing 100 lbs; of red herrings, twenty cades, or 20,000; of hides, twelve dozen; of leather, twenty dickers; of pitch and tar, fourteen barrels; of wool, twelve sacks; of flax or feathers, 1,700 lbs.
(n.) The burden of a ship; a cargo.
Example Sentences:
(1) These data indicate a steady improvement in laboratory performance over the last 10 years.
(2) City badly missed Yaya Touré, on international duty at the Africa Cup of Nations, and have not won a league match since last April when he has been missing.
(3) Future Brown have connections in the fashion industry, last year soundtracking a surreal film for the brand Telfar.
(4) "This is the third event in the last few days following An-26 and SU-25 planes being brought down.
(5) Peripheral vascular surgery has become an increasingly common mode of treatment in non-university, community hospitals in Sweden during the last decade.
(6) Michael Schumacher’s manager hopes F1 champion ‘will be here again one day’ Read more Last year, Red Bull were frustrated by Mercedes, Ferrari and Honda as they desperately looked for a new engine supplier.
(7) In each study, all subjects underwent four replications (over two days) of one of the six permutations of the three experimental conditions; each condition lasted 5 min.
(8) Mike Ashley told Lee Charnley that maybe he could talk with me last week but I said: ‘Listen, we cannot say too much so I think it’s better if we wait.’ The message Mike Ashley is sending is quite positive, but it was better to talk after we play Tottenham.” Benítez will ask Ashley for written assurances over his transfer budget, control of transfers and other spheres of club autonomy, but can also reassure the owner that the prospect of managing in the second tier holds few fears for him.
(9) All the patients told about a comfortable feeling of warmth after each treatment lasting for one two days.
(10) It comes in defiant journalism, like the story televised last week of a gardener in Aleppo who was killed by bombs while tending his roses and his son, who helped him, orphaned.
(11) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(12) I would immediately look askance at anyone who lacks the last and possesses the first.
(13) David Cameron last night hit out at his fellow world leaders after the G8 dropped the promise to meet the historic aid commitments made at Gleneagles in 2005 from this year's summit communique.
(14) A new propaganda video by Islamic State featuring the British photojournalist John Cantlie, in which he says it is the “last film in this series”, has appeared online.
(15) Maternal diabetes and antihistamine use during the last 2 weeks of pregnancy were associated with significantly higher rates of retrolental fibroplasia, whereas toxemia was associated with lower rates.
(16) A review is presented concerning the development of new neuroimaging techniques in the last decade which have improved the diagnostic exploration of patients with spinal cord injuries, including studies of possible sequelae.
(17) The discussion on topics like post-schooling and rehabilitation of motorists has intensified the contacts between advocates of traffic law and traffic psychologists in the last years.
(18) Though the 54-year-old designer made brief returns to the limelight after his fall from grace, designing a one-off collection for Oscar de la Renta last year , his appointment at Margiela marks a more permanent comeback.
(19) In a Bloomberg article last week, for example, one Stanford student compared women who get raped to unlocked bicycles : ‘Do I deserve to have my bike stolen if I leave it unlocked on the quad?’ [Chris] Herries, 22, said.
(20) Mary's grief, which lasts for about the first half of the two-hour premiere special, is the finest work of the series so far by Michelle Dockery.
Mast
Definition:
(n.) The fruit of the oak and beech, or other forest trees; nuts; acorns.
(n.) A pole, or long, strong, round piece of timber, or spar, set upright in a boat or vessel, to sustain the sails, yards, rigging, etc. A mast may also consist of several pieces of timber united by iron bands, or of a hollow pillar of iron or steel.
(n.) The vertical post of a derrick or crane.
(v. t.) To furnish with a mast or masts; to put the masts of in position; as, to mast a ship.
Example Sentences:
(1) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(2) In later phases, mast cells appeared in the newly formed marrow in the external callus.
(3) Our prospective study has defined a number of important variables in patients with clinical evidence of mast cell proliferation that can predict both the presence of SMCD and the likelihood of fatal disease.
(4) In the dark cortical zone of the nodes (III group) there occur tissue basophils (mast cells), that, together with increasing number of acidophilic granulocytes and appearance of neutrophilic cells, demonstrates that there is an inflammatory reaction in the organ studied as a response to the lymphocytic suspension injected.
(5) Type I and Type II mast-cell degranulation was noted but was not universal.
(6) They clearly demonstrate the phenomenon of mast cells degranulation.
(7) The early absolute but transient dependence of these A-MuLV mast cell transformants on a fibroblast feeder suggests a multistep process in their evolution, in which the acquisition of autonomy from factors of mesenchymal cell origin may play an important role.
(8) The findings suggest that mast cell prostaglandins are an important factor in the pathogenesis of pruritus and that local vascular responses may trigger mast cell degranulation.
(9) 18 patients with typical sporadic Amyotrophic Lateral Sclerosis (ALS) were investigated by the Motor Accuracy and Speed Test (MAST) and 18 healthy age- and-sex-matched volunteers, acted as controls.
(10) When PMC purified to greater than 99% purity were cultured in methylcellulose with IL-3 and IL-4, approximately 25% of the PMC formed colonies, all of which contained both berberine sulfate-positive and berberine sulfate-negative mast cells.
(11) But we sent out reconnoitres in the morning; we send out a team in advance and they get halfway down the road, maybe a quarter of the way down the road, sometimes three-quarters of the way down the road – we tried this three days in a row – and then the shelling starts and while I can’t point the finger at who starts the shelling, we get the absolute assurances from the Ukraine government that it’s not them.” Flags on all Australian government buildings will be flown at half-mast on Thursday, and an interdenominational memorial service will be held at St Patrick’s cathedral in Melbourne from 10.30am.
(12) Mice homozygous for mutations at either locus exhibit several phenotypic abnormalities including a virtual absence of mast cells.
(13) This initial observation of release of eosinophil chemotactic factor of anaphylaxis in vivo along with histamine assigns the mast cell a central role in cold urticaria.
(14) Their presence was established both by staining for mast cells at light microscopic level and by electron microscopy.
(15) Pretreatment of rat peritoneal mast cells with either Staurosporine or an analog K-252a, lead to a dose-related inhibition of histamine release when stimulated with Anti-IgE (IC50: Staurosporine = 110 nM; K-252a = 100 nM).
(16) The ammoniacal silver method, which identifies basic proteins, gives a positive reaction in cytoplasmic granules of rat peritoneal mast cells.
(17) Cytokine secretion by activated lymphocytes or mast cells is preceded by dramatic stabilization of the normally labile GM-CSF mRNA.
(18) Forty-seven patients were brought to the Emergency Department with a good blood pressure which probably would not have existed without the use of MAST Trousers.
(19) Furthermore, using rat mast cells, the binding assay in conjunction with histamine releasing assay may be utilized to predict the in vivo histamine releasing potential of new LHRH peptides which are of clinical importance.
(20) Six dogs had increased numbers of mast cells in peripheral blood or buffy coat smears.