(3d pers. sing. pres.) of Last, to endure, contracted from lasteth.
(a.) Being after all the others, similarly classed or considered, in time, place, or order of succession; following all the rest; final; hindmost; farthest; as, the last year of a century; the last man in a line of soldiers; the last page in a book; his last chance.
(a.) Next before the present; as, I saw him last week.
(a.) Supreme; highest in degree; utmost.
(a.) Lowest in rank or degree; as, the last prize.
(a.) Farthest of all from a given quality, character, or condition; most unlikely; having least fitness; as, he is the last person to be accused of theft.
(a.) At a time or on an occasion which is the latest of all those spoken of or which have occurred; the last time; as, I saw him last in New York.
(a.) In conclusion; finally.
(a.) At a time next preceding the present time.
(v. i.) To continue in time; to endure; to remain in existence.
(v. i.) To endure use, or continue in existence, without impairment or exhaustion; as, this cloth lasts better than that; the fuel will last through the winter.
(v. i.) A wooden block shaped like the human foot, on which boots and shoes are formed.
(v. t.) To shape with a last; to fasten or fit to a last; to place smoothly on a last; as, to last a boot.
(n.) A load; a heavy burden; hence, a certain weight or measure, generally estimated at 4,000 lbs., but varying for different articles and in different countries. In England, a last of codfish, white herrings, meal, or ashes, is twelve barrels; a last of corn, ten quarters, or eighty bushels, in some parts of England, twenty-one quarters; of gunpowder, twenty-four barrels, each containing 100 lbs; of red herrings, twenty cades, or 20,000; of hides, twelve dozen; of leather, twenty dickers; of pitch and tar, fourteen barrels; of wool, twelve sacks; of flax or feathers, 1,700 lbs.
(n.) The burden of a ship; a cargo.
Example Sentences:
(1) These data indicate a steady improvement in laboratory performance over the last 10 years.
(2) City badly missed Yaya Touré, on international duty at the Africa Cup of Nations, and have not won a league match since last April when he has been missing.
(3) Future Brown have connections in the fashion industry, last year soundtracking a surreal film for the brand Telfar.
(4) "This is the third event in the last few days following An-26 and SU-25 planes being brought down.
(5) Peripheral vascular surgery has become an increasingly common mode of treatment in non-university, community hospitals in Sweden during the last decade.
(6) Michael Schumacher’s manager hopes F1 champion ‘will be here again one day’ Read more Last year, Red Bull were frustrated by Mercedes, Ferrari and Honda as they desperately looked for a new engine supplier.
(7) In each study, all subjects underwent four replications (over two days) of one of the six permutations of the three experimental conditions; each condition lasted 5 min.
(8) Mike Ashley told Lee Charnley that maybe he could talk with me last week but I said: ‘Listen, we cannot say too much so I think it’s better if we wait.’ The message Mike Ashley is sending is quite positive, but it was better to talk after we play Tottenham.” Benítez will ask Ashley for written assurances over his transfer budget, control of transfers and other spheres of club autonomy, but can also reassure the owner that the prospect of managing in the second tier holds few fears for him.
(9) All the patients told about a comfortable feeling of warmth after each treatment lasting for one two days.
(10) It comes in defiant journalism, like the story televised last week of a gardener in Aleppo who was killed by bombs while tending his roses and his son, who helped him, orphaned.
(11) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(12) I would immediately look askance at anyone who lacks the last and possesses the first.
(13) David Cameron last night hit out at his fellow world leaders after the G8 dropped the promise to meet the historic aid commitments made at Gleneagles in 2005 from this year's summit communique.
(14) A new propaganda video by Islamic State featuring the British photojournalist John Cantlie, in which he says it is the “last film in this series”, has appeared online.
(15) Maternal diabetes and antihistamine use during the last 2 weeks of pregnancy were associated with significantly higher rates of retrolental fibroplasia, whereas toxemia was associated with lower rates.
(16) A review is presented concerning the development of new neuroimaging techniques in the last decade which have improved the diagnostic exploration of patients with spinal cord injuries, including studies of possible sequelae.
(17) The discussion on topics like post-schooling and rehabilitation of motorists has intensified the contacts between advocates of traffic law and traffic psychologists in the last years.
(18) Though the 54-year-old designer made brief returns to the limelight after his fall from grace, designing a one-off collection for Oscar de la Renta last year , his appointment at Margiela marks a more permanent comeback.
(19) In a Bloomberg article last week, for example, one Stanford student compared women who get raped to unlocked bicycles : ‘Do I deserve to have my bike stolen if I leave it unlocked on the quad?’ [Chris] Herries, 22, said.
(20) Mary's grief, which lasts for about the first half of the two-hour premiere special, is the finest work of the series so far by Michelle Dockery.
Prolong
Definition:
(a.) To extend in space or length; as, to prolong a line.
(a.) To lengthen in time; to extend the duration of; to draw out; to continue; as, to prolong one's days.
(a.) To put off to a distant time; to postpone.
Example Sentences:
(1) Without medication atypical ventricular tachycardia develops, in the author's opinion, most probably when bradycardia has persisted for a prolonged period.
(2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(3) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
(4) Morphological alterations in the lungs of pheasants after prolonged high-dosage administration of bleomycin sulfate were studied by light and electron microscopy.
(5) Graft life is even more prolonged with patch angioplasty at venous outflow stenoses or by adding a new segment of PTFE to bypass areas of venous stenosis.
(6) We evaluated the circadian pattern of gastric acidity by prolonged intraluminal pHmetry in 15 "responder" and 10 "nonresponder" duodenal ulcer patients after nocturnal administration of placebo, ranitidine, and famotidine.
(7) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(8) Prolonged immobilization was accompanied by a decrease in Ca-concentration dependence of Ca2+ uptake.
(9) Defibrotide prevents the dramatic fall of creatine phosphokinase activity in the ischemic ventricle: metabolic changes which reflect changes in the cells affected by prolonged ischemia.
(10) With prolonged ischemia, it is only transient and is followed by a gradual loss of the adenylyl cyclase activity.
(11) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(12) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(13) This condition may be caused by the prolonged, repetitive elevations of gonadal steroids and other hormones known to suppress gonadotropin-releasing hormone secretion that are elicited by their daily exercise.
(14) There was no correlation between disturbed gastric clearance, impaired gall bladder contraction, and prolonged colonic transit time in the patients with cardiovascular autonomic neuropathy nor was there a correlation between any disturbed motor function and age or duration of diabetes.
(15) Attempts were made to prolong the survival of the grafts by the use of cytotosine arabinoside, methylprednisolone, heparin and azathioprine.
(16) Because of these different direct and indirect actions, a sudden cessation of sinus node activity or sudden AV block may result in the diseased heart in a prolonged and even fatal cardiac standstill, especially if the tolerance to ischemia of other organs (notably the brain) is decreased.
(17) The 14-fold increase in prolonged apnea frequency immediately following regurgitation supports the hypothesis for a causal relationship between apnea and regurgitation.
(18) Chromatolysis and swelling of the cell bodies of cut axons are more prolonged than after optic nerve section and resolve in more central regions of retina first.
(19) Cryopreserved autologous blood cells may thus restore some patients with CGL in transformation to chronic-phase disease and so may help to prolong life.
(20) Heparin prolonged by 15 s and 45 s the time required to demonstrate Factor V activation in CAP supplemented with Factor Xa and thrombin respectively.