(a.) Smallest, either in size or degree; shortest; lowest; most unimportant; as, the least insect; the least mercy; the least space.
(adv.) In the smallest or lowest degree; in a degree below all others; as, to reward those who least deserve it.
(conj.) See Lest, conj.
Example Sentences:
(1) The most actively proliferating region of the excurrent duct system is zone 3 of the epididymis, whereas the least active region is the ductuli efferentes.
(2) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(3) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
(4) These results show that the pathogenic phenotypes of MCF viruses are dissociable from the thymotropic phenotype and depend, at least in part, upon the enhancer sequences.
(5) These organic compounds were found to be stable on the sorbent tubes for at least seven days.
(6) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(7) The patients should have received treatment for at least seven days and they should not be "ill".
(8) Extensive studies during recent years have shown that the interaction between hormone and membrane-bound receptor can affect the receptor characteristics in at least two ways.
(9) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(10) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(11) For his lone, perilous journey that defied the US occupation authorities, Burchett was pilloried, not least by his embedded colleagues.
(12) In 22 cases (63%), retinal detachment was at least partially flattened in the area of the posterior pole of the eye.
(13) An experimental Anaplasma marginale infection was induced in a splenectomized mule deer (Odocoileus hemionus hemionus) which persisted subclinically at least 376 days as detected by subinoculation into susceptible cattle.
(14) The family comprises at least three variable (V) gene segments, three constant (C) gene segments, and three junction (J) gene segments.
(15) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(16) In vivo studies were performed in five healthy subjects for at least 3 h after ingestion of radiolabeled meals.
(17) Ryzhkov added: "I believe they want to keep him in prison for another three or four years at least, so he is not released until well after the next presidential elections in 2012."
(18) Patients served as their individual control based on observations of at least 1 year before the study.
(19) The reproducibility of the killing-curve method suggests that at least two different concentrations should be used and that a decrease in viable counts below 2 log10 after 24 hours does not exclude a synergistic action.
(20) She was not aware that it was an assassination attempt by alleged foreign agents.” If at least one of the women thought the killing was part of an elaborate prank, it might explain the “LOL” message emblazoned in large letters one of the killers t-shirts.
Minimum
Definition:
(n.) The least quantity assignable, admissible, or possible, in a given case; hence, a thing of small consequence; -- opposed to maximum.
Example Sentences:
(1) Propranolol resulted in a significantly lower mean hourly, mean 24 h and minimum heart rate.
(2) The move would require some secondary legislation; higher fines for employers paying less than the minimum wage would require new primary legislation.
(3) These results suggest that a certain minimum level of expression of c-myc is required for the maintenance of ras transformation in NIH 3T3 cells.
(4) Due to continued disease relapse in this group (four of eight patients), long-term survivors should not be identified for a minimum of 3.5 years from the time of initial therapy.
(5) At concentrations several hundredfold higher than the equivalents present in the minimum concentration of rat skin soluble collagen required for platelet aggregation, neither Hyl-Gal (at 29 muM) nor Hyl-Gal-Glc (at 18 muM) caused platelet aggregation or inhibited platelet aggregation by native collagen.
(6) The morbidity is well known and if properly anticipated can be reduced to a minimum by judicious use of antibacterial agents and early surgical intervention when appropriate.
(7) Analysis was performed on all patients who received any amount of therapy (VSG) and on the Adequately Treated Group (ATG), who had received 5000 or more rads radiotherapy, two or more courses of chemotherapy, and had a minimum survival of 8 or more weeks (the interval that would have been required to have received either the radiotherapy or chemotherapy).
(8) However, the effect of prior jaw motion and the effect of the recording site on the EMG amplitudes and on the vertical dimension of minimum EMG activity have not been documented.
(9) Leaders of Tory local government are preparing radical proposals for minimum 10% cuts in public spending in the search for savings.
(10) It was shown that the levels of ATP and ADP in the mycelium depended on the carbon source: the maximum and minimum ATP concentrations were found on the glucose and acetate media respectively, the maximum and minimum ADP concentrations showed inverse dependence.
(11) On the tangential views the inclinations of the future implants were estimated and the part of the alveolar ridge having a width less than 5 mm, which is the minimum width for housing an implant, was compiled.
(12) The activity was maximum at the 16-32-cell stage and then decreased to a minimum at the mesenchyme blastula stage.
(13) Minimum investment is £200, and the share prospectus states that interest of 6% will be paid from year three of trading.
(14) The 30-fold chromosomally mediated and 15-fold R-plasmid NT resistance were 3- and 5-fold respectively reduced by a minimum inhibitory combination of Tp + NT.
(15) Minimum inhibitory concentrations for these four antibiotics have been determined against 393 bacterial strains (13 species from eight genera) isolated from clinical materialKanamycin was the least active, 89% of the Pseudomonas aeruginosa strains being resistant.
(16) The number of seats has been reduced from 72,000 to 68,000, with another 12,000 to be added after the Games to meet the 80,000 minimum required in case Japan launches a bid to host the football World Cup.
(17) A minimum of 4 sheeps' heads, obtained weekly over 24 months from the Pretoria Municipal Abattoir, was examined for infestation.
(18) Variations in bioavailability and intestinal absorption are important factors in the determination of dosage and should be reduced to a minimum by improved pharmaceutical formulations.
(19) With a minimum review period of 6 months complete remission of synovitis was obtained in 20%, while 63% gained symptomatic relief, with some reduction of synovitis.
(20) The minimum contraction produced by the threshold current involved usually three or four, sometimes two, sarcomers on both sides of the injecting pipette but contraction involving only one sarcomere was not observered.