(a.) Smallest, either in size or degree; shortest; lowest; most unimportant; as, the least insect; the least mercy; the least space.
(adv.) In the smallest or lowest degree; in a degree below all others; as, to reward those who least deserve it.
(conj.) See Lest, conj.
Example Sentences:
(1) The most actively proliferating region of the excurrent duct system is zone 3 of the epididymis, whereas the least active region is the ductuli efferentes.
(2) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(3) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
(4) These results show that the pathogenic phenotypes of MCF viruses are dissociable from the thymotropic phenotype and depend, at least in part, upon the enhancer sequences.
(5) These organic compounds were found to be stable on the sorbent tubes for at least seven days.
(6) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(7) The patients should have received treatment for at least seven days and they should not be "ill".
(8) Extensive studies during recent years have shown that the interaction between hormone and membrane-bound receptor can affect the receptor characteristics in at least two ways.
(9) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(10) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(11) For his lone, perilous journey that defied the US occupation authorities, Burchett was pilloried, not least by his embedded colleagues.
(12) In 22 cases (63%), retinal detachment was at least partially flattened in the area of the posterior pole of the eye.
(13) An experimental Anaplasma marginale infection was induced in a splenectomized mule deer (Odocoileus hemionus hemionus) which persisted subclinically at least 376 days as detected by subinoculation into susceptible cattle.
(14) The family comprises at least three variable (V) gene segments, three constant (C) gene segments, and three junction (J) gene segments.
(15) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(16) In vivo studies were performed in five healthy subjects for at least 3 h after ingestion of radiolabeled meals.
(17) Ryzhkov added: "I believe they want to keep him in prison for another three or four years at least, so he is not released until well after the next presidential elections in 2012."
(18) Patients served as their individual control based on observations of at least 1 year before the study.
(19) The reproducibility of the killing-curve method suggests that at least two different concentrations should be used and that a decrease in viable counts below 2 log10 after 24 hours does not exclude a synergistic action.
(20) She was not aware that it was an assassination attempt by alleged foreign agents.” If at least one of the women thought the killing was part of an elaborate prank, it might explain the “LOL” message emblazoned in large letters one of the killers t-shirts.
Ultimate
Definition:
(a.) Farthest; most remote in space or time; extreme; last; final.
(a.) Last in a train of progression or consequences; tended toward by all that precedes; arrived at, as the last result; final.
(a.) Incapable of further analysis; incapable of further division or separation; constituent; elemental; as, an ultimate constituent of matter.
(v. t. & i.) To come or bring to an end; to eventuate; to end.
(v. t. & i.) To come or bring into use or practice.
Example Sentences:
(1) Even former Florida governor Jeb Bush, one of Trump’s chief critics, said ultimately, “anybody is better than Hillary Clinton”.
(2) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(3) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(4) It is found that, whereas the spatial resolution achievable with such a system is only dependent upon its temporal resolution, the scattering characteristics of the tissue being imaged will strongly affect the ultimate imaging performance of such a system.
(5) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(6) The citizenship debate is tawdry, conflated and ultimately pointless | Richard Ackland Read more On Wednesday, the prime minister criticised lawyers for backing terrorists.
(7) Hydroperoxides from arachidonic acid can decompose via this mechanism to form leukotrienes of potential biological significance and can catalyze the epoxidation of proximal carcinogens to ultimate carcinogenic metabolites.
(8) Ultimate nonsurvivors of ICU admission (36 per cent) had shorter out-of-hospital times, shorter travel distances, and increased interventional support, as assessed by the Therapeutic Intervention Scoring System applied over the telephone and prior to departure at the referring hospital.
(9) Ultimately, prevention is a better approach than cure.
(10) Twenty-three cases were reviewed with an ultimate amputation rate of 61% (22% primary, 39% delayed).
(11) Ultimately, both Geffen and Browne turned out to be correct: establishing the pattern for Zevon's career, the albums sold modestly but the critics loved them.
(12) Differential degeneration of the lateral microvessels may account for increases in collagen nodule growth and ultimate size.
(13) The sensitivity of a PCR system to amplify the long terminal repeat (LTR) sequence of HIV-1 was not affected by the irradiation procedure; however, the ultimate sensitivity of a PCR system for the amplification of an early gene promotor sequence of the CMV genome was reduced 1000-fold.
(14) Both sides sought a decisive goal in a frenetic finish but ultimately the league leaders and the side fighting relegation shared the points and Mourinho wound up making dark allusions to the influence of officials .
(15) The ultimate mutagenic form(s) are therefore unlikely to be acetoxyarylamines.
(16) The finding confirms that procarcinogenic dialkyl aryltriazenes must be enzymatically converted into reactive metabolites, presumably into the corresponding monoalkyltriazenes, which ultimately react with tRNA.
(17) Do get yourself elected as a governor If you’re lucky, your school hasn’t yet been swallowed up by a private academy chain, and so its governing body still has ultimate power, and the headteacher is accountable to it.
(18) A 73-year-old woman who presented with primary adrenal insufficiency and enlarged adrenal glands on computed tomographic scanning was ultimately found to have a large-cell lymphoma that had initially involved the adrenals and the stomach.
(19) Psychiatric testimony to ultimate questions at law is limited by the inherent contextual variables of psychiatric clinical and experimental knowledge and practice.
(20) Ultimately, the judgments combine to make a particularly peculiar melange: among the plaintiffs there is a mix of economic pessimism and insecure nationalism with a shot of nostalgia for the Deutschmark.