(n.) One of the higher alcohols of the paraffine series obtained from spermaceti as a white crystalline solid. It is so called because it occurs in the ethereal salt of lauric acid.
(a.) Deadly; mortal; fatal.
Example Sentences:
(1) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(2) In more than 70 per cent of these, brain injury is the decisive lethal factor.
(3) One rat strain (TAS) is susceptible to the anticoagulant and lethal effects of warfarin and the other two strains are homozygous for warfarin resistance genes from either wild Welsh (HW) or Scottish (HS) rats.
(4) The results are consistent with our previous suggestion that lethality for virulent SFV infection results from a lethal threshold of damage to neurons in the CNS and that attenuating mutations may reduce neuronal damage below this threshold level.
(5) Osteogenesis imperfecta is the common term for a heterogeneous group of heritable disorders of connective tissue with lethal and nonlethal forms.
(6) It was recently demonstrated that MRL-lpr lymphoid cells transferred into lethally irradiated MRL- +mice unexpectedly failed to induce the early onset of lupus syndrome and massive lymphadenopathy of the donor, instead they caused a severe wasting syndrome resembling graft-vs-host (GvH) disease.
(7) The marine vibrio alone is a powerful stimulus to mucus secretion but lethal for the host.
(8) In-vivo data are limited primarily to dominant lethal studies in rats and some in-vivo alkaline elution results.
(9) None of these MAbs showed any virus-neutralizing activity in vitro; however, mice passively immunized with the purified MAbs were protected from lethal infection by the JHM strain of mouse hepatitis virus.
(10) A variation of a procedure for localized mutagenesis (Hong and Ames, 1971) was employed to generate conditional lethal mutants in phosphatidylserine decarboxylase.
(11) A highly significant correlation was observed between neutralization of indirect hemolysis and neutralization of lethal activity.
(12) A retrospective study was conducted into 136 patients who had received surgical treatment for perforated gastroduodenal ulcers, with the view to establishing postoperative lethality and morbidity (comparing simple suturing with definitive ulcer surgery).
(13) These measures excluded unfavourable lethal outcomes even in cases complicated by Gayet-Wernicke encephalopathy.
(14) Frequency and localization of spontaneous and induced by high temperature (37 degrees C) recessive lethal mutations in X-chromosome of females belonging to the 1(1) ts 403 strain defective in synthesis of heat-shock proteins (HSP) were studied.
(15) As a consequence of deformation from spherical-to-cylindrical shape in the microvasculature, demands for increased surface membrane area leads to increases in surface membrane tension above critical levels for rupture, and the cancer cells are rapidly and lethally damaged.
(16) In almost 80% of sudden cardiac deaths in ACMP foci of acute myocardial ischemia are found, that can lead to ventricular fibrillation with lethal outcome.
(17) Analysis of the literature data on the use of various therapeutic approaches to the treatment of febrile schizophrenia has shown that so far psychiatry does not possess such methods of treatment which could allow the complete prevention of lethal outcomes in this disease.
(18) Our previous results have shown that SC injection of DHEA resulted in upregulation of the specific host immune response resulting in protection against a lethal infection.
(19) Recently, this laboratory has demonstrated an enhanced susceptibility toward the development of ischemia-related lethal ventricular arrhythmias in the presence of therapeutic serum concentrations of digoxin in conscious dogs after myocardial infarction.
(20) The results are discussed in terms of possible conjugation-associated changes that, at high Hfr to F(-) ratios, lead to lethal zygosis.
Spermaceti
Definition:
(n.) A white waxy substance obtained from cavities in the head of the sperm whale, and used making candles, oilments, cosmetics, etc. It consists essentially of ethereal salts of palmitic acid with ethal and other hydrocarbon bases. The substance of spermaceti after the removal of certain impurities is sometimes called cetin.
Example Sentences:
(1) A repository dosage form was devised that consisted of an s.c. implant of pyridoxal phosphate suspended in a spermaceti and peanut oil mixture.
(2) The complex represents the most important factor in the morphogenesis and growth of the characteristic big forehead in Physeter, which contains the spermaceti organ unique within the odontocetes.
(3) In examining further, methadone hydrochloride suspensions were developed using spermaceti or eudragit retard-1 for particle coating.
(4) Nevertheless, these differences have to be taken as specializations related to the development of the far-advanced spermaceti organ.
(5) When I opened it, I found block after block of solid, pure, spermaceti wax , the solidified oil from the sperm whale’s head.
(6) So fine is spermaceti oil that Nasa used it in their space mission, as it does not freeze in outer space.