(1) The possible involvement of a melatonergic mechanism in the control of intraocular pressure (IOP) and the genesis of light-induced avian glaucoma (LIAG) was studied by measuring N-acetyltransferase (NAT) activity and melatonin levels in the iris, ciliary body and retina-choroid during the course of LIAG development, and in normal subjects by day and night.
(2) The results suggest that melatonergic mechanisms could be involved in the elevation of IOP in LIAG.
(3) As well, a prolonged "pre-glaucoma" period is available to the investigator working with LIAG, during which a pathological course is already underway in the eye, but intraocular pressure has not yet gone up.
(4) The corneas showed some characteristic LIAG effects: small anterior chamber depth and increased corneal radius of curvature (flat cornea), as compared with diurnal rc birds.
(5) When rc chicks were reared under continuous light, the environmental condition which brings on LIAG, their already enlarged eyes showed no superimposed increases in either eye weight or globe dimensions.
(6) A number of morphological and physiological findings in LIAG are reviewed, and the LIAG system is compared with several other glaucoma model systems, in dogs, rabbits and monkeys.
(7) The retinal neurotoxin kainic acid rendered chicks behaviorally blind in the eye into which it was injected intravitrially, but this failed to prevent LIAG changes in either anterior segment or growth of the globe.
(8) This further separates the LIAG effect from the phenomenon we call albino quail macrophthalmos.
(9) Preliminary trials with quisqualic acid, another retinal neurotoxin, indicate that this agent, like kainic acid, cannot prevent LIAG eye enlargement.
(10) Thus LIAG globe enlargement, and LSM axial lengthening, appear to be vision-driven, but anterior segment changes are probably separately controlled.
(11) Intraocular pressure in LIAG has been demonstrated to be responsive to several anti-glaucoma drugs, and the system could be used for further drug testing.
(12) Domestic chicks reared under continuous dim light developed the eye enlargement and suppressed corneal growth characteristic of light-induced avian glaucoma (LIAG) and dim light buphthalmos (DLB).
(13) Under LIAG conditions, increased eye weight and global enlargement did not occur, but the characteristic anterior segment changes were seen.
(14) We also explored the relationship between hereditary blindness and two environmental interventions affecting eye development, light-induced avian glaucoma (LIAG) and the axial lengthening associated with lid-suture.
(15) When the rearing conditions were diurnal (ie, not such as to induce LIAG eye enlargement), and the light of at least "normal" brightness, lid suture still caused unilateral myopia, accompanied by a pronounced bulging of the cornea.
(16) Domestic chicks (Gallus domesticus) reared under continuous light, and thus developing light-induced avian glaucoma (LIAG), were tested at 4-hourly intervals around the clock, for evidence of hormonal or other rhythms which might be related to the eye effects of LIAG.
(17) We compared albino (aI), dilute (aID), and wild-type (AI+) quail in their ocular responses to continuous light, the rearing condition that brings on light-induced avian glaucoma (LIAG) in domestic chickens.
(18) No statistical differences in choline acetyltransferase activity, adrenergic transmitter levels or dopamine concentrations could be found in tissues of LIAG eyes vs control eyes, indicating that cholinergic, adrenergic and dopaminergic mechanisms are probably not involved in LIAG.
(19) This light-induced avian glaucoma (LIAG) is presented as an animal model system for human open-angle glaucoma.
(20) Two antiglaucoma drugs were tested on Hubbard chicks with light-induced avian glaucoma (LIAG).
Liege
Definition:
(a.) Sovereign; independent; having authority or right to allegiance; as, a liege lord.
(a.) Serving an independent sovereign or master; bound by a feudal tenure; obliged to be faithful and loyal to a superior, as a vassal to his lord; faithful; loyal; as, a liege man; a liege subject.
(a.) Full; perfect; complete; pure.
(n.) A free and independent person; specif., a lord paramount; a sovereign.
(n.) The subject of a sovereign or lord; a liegeman.
Example Sentences:
(1) This study had for objective to detect the psychological morbidity of 176 non-consulting primiparas in the region of Liege using both the PSE and a sociological questionnaire.
(2) From January 1976 to June 1984, 308 necropsies were performed on neonates and fetuses of various gestational age, mainly coming from hospitals of the province of Liege.
(3) Radio 2 listeners recently voted Liege and Lief the most influential folk album ever.
(4) So Thursday night's "people's festival" in Ghent, a large street party in honour of eight government-free months, with its spoof world championship ceremony, was accompanied by stunts in Brussels and Antwerp, Leuven and Liege in what turned into a Red Nose day aimed at shaming a cynical political elite.
(5) Its designer, Kenjiro Sano, asked that his logo be withdrawn, weeks after a Belgian designer, Olivier Debie, accused him of drawing heavily on own motif for the Theatre de Liege .
(6) Osborne: We haven't got a legacy to stand on … Lansley: I am happy to announce, my liege, that the NHS is now officially a joke … Cameron: Brilliant, Adrian.
(7) Oldham is better known, of course, as that bearded liege lord of modern folk, Bonnie Prince Billy , and when Olsen joined his touring band in 2010 she was at the very other end of the musicians' ladder, an aspirant on the Chicago indie scene who'd not yet done a paid gig.
(8) When Porto signed Mangala from Standard Liege in August 2011, they bought 90% of his economic rights, not 100%.
(9) Updated at 4.44pm GMT 4.43pm GMT "I'm very happy to be sitting next to Leo as well..." Leonardo chuckles and says "Thank you my liege."
(10) After taking a second look at a treatment that was common in 1933 for victims of cluster headaches, a doctor from Lieges, Belgium, is now training anesthesiologists in the technique of alcoholization of the sphenopalatine ganglion.
(11) He bought and sold stakes in Standard Liege, Charleroi and Nice before deciding he wanted to own a British club, picking up Portsmouth for £5m in 1998.
(12) Although closely related (r = 0.68), the use of these two parameters in a single scale, the Glasgow-Liege scale, improves the precision of prognosis, especially for those head trauma patients with initial and complete loss of consciousness.
(13) But the Duke has for six decades honoured his own vow on that day to be "your liege man of life and limb, and of earthly worship", and he wasn't going to let her down now.
(15) The 29-year-old DR Congo international, four times a Belgian league champion across his spells with Standard Liege and Anderlecht, will move to Carrow Road pending the approval of a work permit.
(16) The complete pedigree indicates that Hb D-Los Angeles was already present in Liege province in the 18th century.
(17) Fellaini cost around €19m (£16m at the present rate) with add-ons when Moyes bought the Belgian midfielder to Everton from Standard Liege in 2008.
(18) The author complemented the AMDP-4 scale by some somatic items from the Liege psychiatric record, the code of Devroye, Pinchard and Timsit.
(19) The phenotypes of C3 and of Tf were determined in 818 and 576, respectively, unrelated individuals living in Liege.
(20) Eighty nine patients with hypoxic chronic obstructive airways disease (COAD) were enrolled into the 1 year Vectarion International Multicentre Study-VIMS in 4 centres, Sheffield (UK), and Antwerp, Liege and Namur (Belgium).