What's the difference between linkage and tie?

Linkage


Definition:

  • (n.) The act of linking; the state of being linked; also, a system of links.
  • (n.) Manner of linking or of being linked; -- said of the union of atoms or radicals in the molecule.
  • (n.) A system of straight lines or bars, fastened together by joints, and having certain of their points fixed in a plane. It is used to describe straight lines and curves in the plane.

Example Sentences:

  • (1) The presence of O-glycosidic linkages between carbohydrate and protein in the DF3 antigenic site was further supported by the presence of NaBH4-sensitive sites.
  • (2) Twelve families with Wiskott-Aldrich syndrome (WAS) were studied by linkage analysis using 10 polymorphic marker loci from the X-chromosome pericentromeric region.
  • (3) A complex linkage between the cytoskeleton and the extracellular matrix is illustrated both in the cord forming Sertoli and granulosa cells, and in the adjacent mesenchymal cells.
  • (4) The assumption was also corroborated using reagents from a family in which DR3 and DQw2 were not found in the usually described linkage.
  • (5) This linkage information was used to design complementation tests to determine allelism with previously characterized complementation groups affecting sensitivity to radiation.
  • (6) Sensitivity and specificity were enhanced when we linked multiple predictors, but this linkage was seldom successful because few patients had more than one positive predictor.
  • (7) Analysis of the product by equilibrium density centrifugation and processive hydrolysis with snake venom phosphodiesterase suggested that the noncomplementary nucleotides were present in phosphodiester linkage.
  • (8) The same segments have been described to be responsible for the hexamer-hexamer linkage (Yu, M.-H. & Glazer, A.N.
  • (9) The two disorders may associate within families through genetic linkage or a failure of neurotransmitter homoeostasis.
  • (10) Isopycnic analyses of the ribonucleotide initiated fd DNA replication products demonstrated covalent linkage between the initiator RNA and newly synthesized DNA.
  • (11) The others had the structures galactosyl-galactosyl-xylosyl-4-methylumbelliferone and galactosyl-xylosyl-4-methylumbelliferone, respectively, representing the linkage region between the glycosaminoglycan chains and core protein, except that 4-methylumbelliferone replaced the amino acid.
  • (12) Absence of linkage in a large group of families shows that lamp genes are not involved in Salla disease.
  • (13) Because each linkage project is different, the modular nature of the software allows for better control of the programming process and development of unique strategies.
  • (14) Family clustering suggests a genetic pathogenesis, but linkage to HLA or other blood group markers has not been found.
  • (15) Biosynthesis of the two N-glycosyl linkage units involves dolichol monophosphate and dolicholdiphosphate-linked saccharide precursors.
  • (16) In addition, the distances between markers in the mouse and human were similar except for one region of the conserved linkage group where we could detect a larger distance in the mouse compared to the human.
  • (17) The inter-connecting linkage system develops postnatally, and the 'tip-linkages' are already found in one-week-old mice, suggesting that the critical organization of the micromechanics of the stereocilia matures rapidly during the postnatal period.
  • (18) Using molecular probes to examine somatic cell lines and recombinant inbred and congenic strains of mice, we have re-evaluated these linkage relationships.
  • (19) We now report linkage between CF and pJ3.11 (Z = 4.92, theta = 0) and between CF and 7C22 (Z = 3.42, theta = 0).
  • (20) Recently, a gene for ITD (DYT1) in a non-Jewish kindred was located on chromosome 9q32-34, with tight linkage to the gene encoding gelsolin (GSN).

Tie


Definition:

  • (v. t.) A knot; a fastening.
  • (v. t.) A bond; an obligation, moral or legal; as, the sacred ties of friendship or of duty; the ties of allegiance.
  • (v. t.) A knot of hair, as at the back of a wig.
  • (v. t.) An equality in numbers, as of votes, scores, etc., which prevents either party from being victorious; equality in any contest, as a race.
  • (v. t.) A beam or rod for holding two parts together; in railways, one of the transverse timbers which support the track and keep it in place.
  • (v. t.) A line, usually straight, drawn across the stems of notes, or a curved line written over or under the notes, signifying that they are to be slurred, or closely united in the performance, or that two notes of the same pitch are to be sounded as one; a bind; a ligature.
  • (v. t.) Low shoes fastened with lacings.
  • (v. t.) To fasten with a band or cord and knot; to bind.
  • (v. t.) To form, as a knot, by interlacing or complicating a cord; also, to interlace, or form a knot in; as, to tie a cord to a tree; to knit; to knot.
  • (v. t.) To unite firmly; to fasten; to hold.
  • (v. t.) To hold or constrain by authority or moral influence, as by knotted cords; to oblige; to constrain; to restrain; to confine.
  • (v. t.) To unite, as notes, by a cross line, or by a curved line, or slur, drawn over or under them.
  • (v. t.) To make an equal score with, in a contest; to be even with.
  • (v. i.) To make a tie; to make an equal score.

Example Sentences:

  • (1) Behind her balcony, decorated with a flourishing pothos plant and a monarch butterfly chrysalis tied to a succulent with dental floss, sits the university’s power plant.
  • (2) Theresa May signals support for UK-EU membership deal Read more Faull’s fix, largely accepted by Britain, also ties the hands of national governments.
  • (3) The quantity of social ties, the quality of relationships as modified by type of intimate, and the baseline level of symptoms measured five years earlier were significant predictors of psychosomatic symptoms among this sample of women.
  • (4) They are just literally lying.” In August Microsoft severed its ties, saying Alec’s stance on climate change and several other issues “conflicted directly with Microsoft’s values”.
  • (5) There is a gradual loosening of the adolescent's emotional dependence on her parents and a transfer of dependency ties to peers.
  • (6) We have reported on a simple and secure method of tying up hair during transplantation surgery for alopecia.
  • (7) Maybe it’s because they are skulking, sedentary creatures, tied to their post; the theatre critic isn’t going anywhere other than the stalls, and then back home to write.
  • (8) Beijing has no interest in seeing strained ties affecting development plans either.” The Moranbong band was founded by Kim Jong-un , with each member reportedly selected by a leader eager to make his mark on the cultural scene.
  • (9) Two years ago I met a wonderful man and we now feel it’s time to tie the knot.
  • (10) The glory lay in the defiance, although the outcome of the tie scarcely looks promising for Arsenal when the return at Camp Nou next Tuesday is borne in mind.
  • (11) Alec played a role in the resignation of the UK defence secretary Liam Fox last year over his close ties to his friend Adam Werritty.
  • (12) The Dodgers and Braves are tied 1-1 in the third inning and the Detroit Tigers and Oakland A's ALDS will start at 9:37pm EST.
  • (13) And if that ties up with one another then Oscar has got a major problem."
  • (14) Los Angeles were relentless in their vicious pursuit of a game-tying goal on Wednesday, bidding to send Game 4 into overtime.
  • (15) "This is the guy we've all seen in Borders or HMV on a Friday afternoon, possibly after a drink or two, tie slightly undone, buying two CDs, a DVD and maybe a book - fifty quid's worth - and frantically computing how he's going to convince his partner that this is a really, really worthwhile investment."
  • (16) The levy would also confirm the dramatically changing nature of Pakistan's ties with its western partners, from a strategic alliance to a transactional relationship, with deep suspicions on both sides.
  • (17) Trade unions criticised the corporation’s 1% offer, tied to a minimum of just £390, for those staff earning under £50,000, calling it “completely unacceptable” .
  • (18) Unlike most CDU politicians, he keeps close ties to the British Conservatives despite their differences on Europe .
  • (19) Last week, the army major who ordered Dar to be tied to the vehicle was awarded a commendation for his counter-insurgency work in the region.
  • (20) He added, however, that the US would "remain the world's leading military and economic power for the next two to three decades" and he ruled out a radical shift in bilateral ties.

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