(1) We have evaluated the effect of the synthetic liquorice derivative, carbenoxolone, on this enzyme complex.
(2) After a wide survey of the literature, the clinical and biological picture in four patients with chronic Liquorice ingestion and Pseudoaldosteronism syndrome is described.
(3) The town is also home to Svaneke Bolcher, where you can watch traditional Danish sweets being made, and Johan Bülow ’s inventive liquorice, which is now sold in shops such as Harvey Nichols and Fortnum & Mason.
(4) These results show that potentially serious metabolic effects may occur in some people who eat modest amounts of liquorice daily for less than a week.
(5) Both tragant sulfate, a pepsin inhibitor, and deglycyrrhizinized liquorice extract proved to be without prophylactic effect.
(6) We have previously demonstrated, in adrenalectomized male rats, that the liquorice derivative carbenoxolone (CS) can confer mineralocorticoid (MC)-like activity upon the glucocorticoid corticosterone (B) and amplify the Na(+)-retaining actions of aldosterone (Aldo) and deoxycorticosterone (DOC).
(7) A case of pseudo-hyperaldosteronism secondary to prolonged daily ingestion of liquorice is reported.
(8) They ate liquorice in daily doses of 100 g or 200 g (equivalent to 0-7-1-4 g glycyrrhizinic acid) for one to four weeks.
(9) The binding of agonists (liquorice derivatives) and antagonists (spironolactones and cyproheptadine) to Type I aldosterone binding sites was evaluated in human mononuclear leucocytes and compared with data previously obtained using kidney cytosol or kidney slices from adrenalectomized rats.
(10) A double-blind trial of deglycyrrhizinated liquorice was performed in 47 patients with active duodenal ulcer.
(11) Bassett's Liquorice Allsorts were created by accident in 1899, when salesman Charlie Thompson tripped up, mixing up all the different sweets he was carrying.
(12) Six geographically diverse samples of liquorice root contained similar (22.2-32.3 mg g-1) glycyrrhizin contents.
(13) These findings seem to explain why sodium retention, hypokalaemia, and hypertension develop in subjects with congenital deficiency of 11 beta-OHSD and those in whom the enzyme has been inhibited by liquorice.
(14) The first example is liquorice root, its active principle carbenoxolone, and the drugs Biogastrone and Caved-S for the treatment of gastic, peptic and duodenal ulcers; the second example is the fruits of the milk thistle, its active principles silymarin and silybinin as well as the drug Legalon for the treatment of liver diseases.
(15) after liquorice ingestion) results in cortisol acting as a potent mineralocorticoid.
(16) No side effects of treatment were observed.Our study was not able to demonstrate any healing effect of the liquorice extract (Caved-S) on gastric ulcer.
(17) The patients were treated during two consecutive periods of four weeks each with either liquorice extract during the first period and placebo during the second or placebo during the first period and liquorice during the second.
(18) Her diva demands do not extend beyond the stage-door staff voluntarily leaving a hand-picked packet of her favourite black liquorice allsorts in her pigeonhole.
(19) When the activity of the enzyme is impaired (syndrome of apparent MC excess, liquorice or carbenoxolone administration), F acts as a MC and MC-hypertension with hypokalemia occurs.
(20) The dosage of the liquorice extract was 760 mg three times daily.