(n.) A tuft of hair; a flock or small quantity of wool, hay, or other like substance; a tress or ringlet of hair.
(n.) Anything that fastens; specifically, a fastening, as for a door, a lid, a trunk, a drawer, and the like, in which a bolt is moved by a key so as to hold or to release the thing fastened.
(n.) A fastening together or interlacing; a closing of one thing upon another; a state of being fixed or immovable.
(n.) A place from which egress is prevented, as by a lock.
(n.) The barrier or works which confine the water of a stream or canal.
(n.) An inclosure in a canal with gates at each end, used in raising or lowering boats as they pass from one level to another; -- called also lift lock.
(n.) That part or apparatus of a firearm by which the charge is exploded; as, a matchlock, flintlock, percussion lock, etc.
(n.) A device for keeping a wheel from turning.
(n.) A grapple in wrestling.
(v. t.) To fasten with a lock, or as with a lock; to make fast; to prevent free movement of; as, to lock a door, a carriage wheel, a river, etc.
(v. t.) To prevent ingress or access to, or exit from, by fastening the lock or locks of; -- often with up; as, to lock or lock up, a house, jail, room, trunk. etc.
(v. t.) To fasten in or out, or to make secure by means of, or as with, locks; to confine, or to shut in or out -- often with up; as, to lock one's self in a room; to lock up the prisoners; to lock up one's silver; to lock intruders out of the house; to lock money into a vault; to lock a child in one's arms; to lock a secret in one's breast.
(v. t.) To link together; to clasp closely; as, to lock arms.
(v. t.) To furnish with locks; also, to raise or lower (a boat) in a lock.
(v. t.) To seize, as the sword arm of an antagonist, by turning the left arm around it, to disarm him.
(v. i.) To become fast, as by means of a lock or by interlacing; as, the door locks close.
Example Sentences:
(1) A bouncy function has now been incorporated into a knee of the semi-automatic knee lock design in a pilot laboratory trial involving six patients.
(2) The only other black woman I see in the building: washing dishes behind a door that was supposed to have been locked.
(3) In contrast, 1:1 phase locking characterized the electrical correlates of the duodenal activity front.
(4) When you hear the name Jesus, is the first image that comes to mind a dewy-eyed pretty boy with flowing locks?
(5) The commonly used line-to-line reaming technique was compared to an underreaming technique using both four-fifths and one-third porous-coated anatomic medullary locking (AML) implants.
(6) Andrew and his wife Amy belong to Generation Rent, an army of millions, all locked out of home ownership in Britain.
(7) While the Spielberg of popular myth is Mr Nice Guy, Lean was known as an obsessive, cantankerous tyrant who didn't much like actors and was only truly happy locked away in the editing suite.
(8) One top Republican official told the Guardian the party has for months been locked in secret talks with TV networks about how – or whether – it will fit all the candidates onstage for the primary debates.
(9) We develop an analogy between the steric hindrance among receptors detecting randomly placed haptens and the temporary locking of a Geiger counter that has detected a radioactive decay.
(10) On Wednesday, managing director Mike Devereux also flagged that the company's future in the country was not certain if government funding was not locked in over a long period.
(11) The violence led to the temporary suspension of the council's monthly meeting with some staff at one stage locked in rooms to ensure their safety.
(12) There have been reports of difficulties with the seating and locking of the vaporisers which can cause a leak and failure of vapour delivery.
(13) Such mutations lead to a major reduction in the rate of GTP hydrolysis by the complex of ras p21 and the GTPase activating protein (GAP) and lock the protein in a growth-promoting state.
(14) He was a fixture at Trump rallies, where he met chants of “Lock her up” against Hillary Clinton with a smile.
(15) No doubt New Labour ministers would regard such moves as protectionism, locked as they are in a discredited free-market mindset.
(16) So-called "structured" savings accounts promoted heavily by banks and building societies promise savers extra interest if they lock their money away for at least five years.
(17) Palmer sought to clarify his statements on Tuesday, and said they were aimed at the company he is currently locked in a dispute with, and not the broader Chinese population.
(18) Foveal exposures that did not produce an immediately visible lesion did not produce measurable changes in VEP response lock-in time.
(19) Scream Queens is the kind of show where you discover a secret locked room in the basement in one scene and then we find out exactly what is in the room three scenes later.
(20) In a group of the MS-DB units with stable background theta bursts the typical response consisting of entrainment of the phase-locked theta cycles was changed neither by physostigmine, nor by cholinergic-blocking drugs (scopolamine and atropine).
Loco
Definition:
(adv.) A direction in written or printed music to return to the proper pitch after having played an octave higher.
(n.) A plant (Astragalus Hornii) growing in the Southwestern United States, which is said to poison horses and cattle, first making them insane. The name is also given vaguely to several other species of the same genus. Called also loco weed.
Example Sentences:
(1) Staplers were used and therefore the choice between resection or amputation was determined by the degree of loco-regional infiltration of the neoplasm.
(2) No patient developed metastases without previous clinically-evident invasive loco-regional disease.
(3) It is of mechanical or mixed type, accompanied by local, pseudo-inflammatory signs being either apparent or discrete, very elective and very sharp pain upon palpation of a very limited area of a condyle or a tibial plate, with hyperfixation located through scintigraphy with technetium 99m polyphosphates, and regressing either spontaneously, or more quickly under treatment, of which thyrocalcitone is the essential part, without undergoing a phase of intense loco-regional demineralization.
(4) There was complete loco-regional tumour control in 51% of all patients (with and without distant metastases).
(5) Two of the 37 patients who underwent mastectomy developed loco-regional recurrences; both had invasive foci at their first operation and remain disease free at 8 years.
(6) Among the 25 cases of recurrence, 1 was exclusively local and 6 were loco-regional (T and N), while 18 patients presented metastatic progression, either exclusively, or with local or lymph node failure.
(7) All patients where managed similarly: 3 to 4 courses of chemotherapy (CMF: n = 24; AVCF: n = 42), then loco regional irradiation therapy with cobalt 60, followed by maintenance chemotherapy, only if the first chemotherapy had proved effective (CMF: n = 13; AVCF: n = 27).
(8) Since there seems to be a direct relation between tumor size and the chance of loco-regional recurrence and since salvage operations for local failure are not uniformly successful, electrofulguration for cure must be reserved for the very rare patient with a very small early-stage rectal cancer.
(9) Although the recurrence rates of 37% and 49% by 50 Gy and 40 Gy were not statistically different, there was a strong trend of a better control rate of loco-regional carcinoma by higher radiation doses.
(10) From these results, it is reasonable to conclude that Kupffer cells alone are activated in a condition without a supply of monocytes from peripheral blood; proliferate and cluster in the hepatic sinusoids; transform into peroxidase-negative macrophages, epithelioid cells, and multinuclear giant cells; and participate in granuloma formation in loco together with T lymphocytes.
(11) Patients with T1 squamous cell carcinomas had, in fact, the best prognosis (26.5% recurred) among the subgroups obtained by stratification of T number and cell type together; loco-regional failure as exclusive modality of relapse had a 5-year rate of 19.7% and metastatic failure of 30.0%.
(12) In patients with Dukes' B tumours, an increased risk of loco-regional recurrence was associated with perineural invasion, tumour located less than 10 cm from the anal verge, patient aged above 70 years, and small tumour size.
(13) An effort was made to neutralize the virus in loco either by infiltration of the inoculation site with povidone-iodine or with monoclonal antibodies, or by cauterization and excision.
(14) To establish whether predictive clinical patterns of disease occur in localized Non-Hodgkin's lymphoma, survival and relapse patterns for 496 patients with stage I and II non-Hodgkin's lymphoma (NHL) treated with loco-regional irradiation (XRT) alone were examined.
(15) Radiotherapy alone may be appropriate treatment for extensive loco-regional tumours or in those that have already metastasized.
(16) Thus, adjuvant systemic treatment alone (chemotherapy or tamoxifen) did not prevent loco-regional recurrences in high-risk patients after mastectomy and axillary lymph node sampling.
(17) Three factors were found to be statistically significant: adjuvant hormonotherapy, loco-regional metastases, adjuvant adriamycin containing regimen (pejorative prognostic factor).
(18) Risk factors for loco-regional relapse (seven cases) included: large tumour bulk, treatment by XRT alone and use of 'limited' radiation fields.
(19) Following initial promising results in terms of loco-regional disease control in this group of high-risk patients, the protocol was extended to include 34 patients defined as having locally extensive disease.
(20) These changes may be related to the endothelial damage present scleroderma patients I the consequent "in loco" activation of blood coagulation may cause the microthrombosis that is very often observed in the earliest phases of the disease.