(v. t.) To make loose; to free from tightness, tension, firmness, or fixedness; to make less dense or compact; as, to loosen a string, or a knot; to loosen a rock in the earth.
(v. t.) To free from restraint; to set at liberty..
(v. t.) To remove costiveness from; to facilitate or increase the alvine discharges of.
(v. i.) To become loose; to become less tight, firm, or compact.
Example Sentences:
(1) There is a gradual loosening of the adolescent's emotional dependence on her parents and a transfer of dependency ties to peers.
(2) The torques, although not large enough to dislodge the socket immediately, are repetitive and so may contribute to loosening.
(3) Femoral endosteal bone loss has been shown to be part of the natural aging process and may be a factor in femoral component loosening following total hip arthroplasty (THA).
(4) Seventeen of these were due to infection or loosening of the prosthesis.
(5) Loosening of the sutures and keratitis were the main complications in the postoperative course.
(6) Electric birefringence studies suggest that methylation may result in both interparticle cross-linking and some localised loosening of the DNA-protein complex complex.
(7) Two tibial components (2%) were believed to be mechanically loose, but no revisions for mechanical loosening were done.
(8) An artificial joint that articulates with full fluid film lubrication could greatly reduce wear and frictional torque and hence reduce the incidence of loosening and inflammatory tissue reaction.
(9) Aseptic loosening is the most common mode of failure for total knee replacements.
(10) The criteria of failure of pedicular instrumentation or "death" of an implant were defined as 1) screw bending, 2) screw breakage, 3) infection, 4) loosening of implants, 5) any rod or plate hardware problems, or 6) removal of hardware due to a neurologic complication.
(11) In the areas of disorganized collagen fibres cervical fibroblasts seemed to be activated characterized by fine granular loosening of the cytoplasma, dilated cisternae of rough endoplasmatic reticulum, vacuolized enlarged mitochondria and an increased number of cytoplasmatic vesicles close to the cell surface.
(12) Loosening of the tightly folded "native" structure of the two proteins following their synthesis in a rabbit reticulocyte lysate was assayed by the acquisition of protease sensitivity (pODHFR and pOCAT) or by the loss of enzyme activity (pOCAT).
(13) We concluded that the acetabular component of the Wagner prosthesis is prone to early loosening and that the early loosening is potentiated by a foreign-body response to debris resulting from arthroplastic wear.
(14) I think that is where we will see the most immediate loosening up of restrictions,” Handjani said.
(15) The reduction in the rate of aseptic loosening of the socket in our series, compared with the higher rates reported in similar long-term studies in which other acetabular components were used, supports the conclusion that there is enhanced longevity of acetabular fixation when a metal-backed acetabular component is used in cemented total hip arthroplasty.
(16) The loosening of such interactions is believed to induce conformational changes, which will alter ion transport systems necessary to the propagation of neural impulses.
(17) Main changes of upper compartments were showed on the bilaminar zone, including disc perforation and anterior displacement and capsular loosening.
(18) Significant problems included abnormal posture in the wrist, roentgenographic evidence of loosening in the finger metacarpophalangeals, extensor lag in the metacarpophalangeal of the thumb, and lack of motion in the proximal interphalangeal joint of the finger.
(19) China's government and media have launched a broadside against Japan's move to loosen the bonds on its powerful military, casting it as a threat to Asian security.
(20) However, because loosening and sinking of the prosthesis were significant, a ceramic total prosthesis was designed in 1980 to be used without cement.
Lose
Definition:
(v. t.) To part with unintentionally or unwillingly, as by accident, misfortune, negligence, penalty, forfeit, etc.; to be deprived of; as, to lose money from one's purse or pocket, or in business or gaming; to lose an arm or a leg by amputation; to lose men in battle.
(v. t.) To cease to have; to possess no longer; to suffer diminution of; as, to lose one's relish for anything; to lose one's health.
(v. t.) Not to employ; to employ ineffectually; to throw away; to waste; to squander; as, to lose a day; to lose the benefits of instruction.
(v. t.) To wander from; to miss, so as not to be able to and; to go astray from; as, to lose one's way.
(v. t.) To ruin; to destroy; as destroy; as, the ship was lost on the ledge.
(v. t.) To be deprived of the view of; to cease to see or know the whereabouts of; as, he lost his companion in the crowd.
(v. t.) To fail to obtain or enjoy; to fail to gain or win; hence, to fail to catch with the mind or senses; to miss; as, I lost a part of what he said.
(v. t.) To cause to part with; to deprive of.
(v. t.) To prevent from gaining or obtaining.
(v. i.) To suffer loss, disadvantage, or defeat; to be worse off, esp. as the result of any kind of contest.
Example Sentences:
(1) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(2) In fact, you might read it as a signal … that the president might well lose on this,” she said.
(3) Shelter’s analysis of MoJ figures highlights high-risk hotspots across the country where families are particularly at risk of losing their homes, with households in Newham, east London, most exposed to the possibility of eviction or repossession, with one in every 36 homes threatened.
(4) The effects of brain injury can be catastrophic and long-term so the impact of more research would be vast, but affected numbers are too small so it loses out.
(5) Larvae from fresh water eggs, cultured in fresh water and 'normal' laboratory cultures reached 50% infectivity in 3-5 days, losing potential infectivity in 11-15 days post-hatching.
(6) He's called out for his lack of imagination in a stinging review by a leading food critic (Oliver Platt) and - after being introduced to Twitter by his tech-savvy son (Emjay Anthony) - accidentally starts a flame war that will lead to him losing his job.
(7) • young clownfish will lose their ability to "smell" the anemone species that they shelter in.
(8) c-WRT-7 cells were found to differentiate into macrophage-like cells and to lose their growth capacity both in vitro and in vivo after incubation with LPS.
(9) By using these larger catheters, the surgeon will not lose the option of using isosmotic preparations.
(10) Winning and losing were predicted to be more significant in determining cardiovascular responses for Type A's than for Type B's.
(11) "I have to say that I have been a Chelsea player since 2004 and I have never had six minutes in my favour when I was losing.
(12) He would still lose some of his original cash, but it would be less.
(13) Moreover, respondents indicating initially relatively high levels of emotional eating who reported a reduction in that level were found to lose significantly (p less than 0.01) more reported weight and to be significantly (p less than 0.05) more successful at approaching target weight over the period of the study than respondents who continued to report high levels of emotional eating.
(14) In addition, we have shown that long-lived, presumably non-senescent, strains do not arise by suppressor mutation, but lose senescence plasmid DNA by another mechanism.
(15) We find that the labelled cell has a myelinated axon, but that the axon loses its myelin within 50 microns of the soma and has not yet been traced further.
(16) Duraphat-treated samples submerged in water after the exposure lost only about 50% of the deposited fluoride, whereas samples treated with 2% NaF are known to lose all their fluoride under similar circumstances, a condition which may be related to the favorable clinical effect of Duraphat.
(17) In the midst of all the newspaper headlines and vigils you can sometimes lose sight of the man who was on death row.
(18) Last month Walsall council announced it would close 15 of its 16 libraries, and residents told the Guardian they stood to lose vital community spaces as well as reading resources.
(19) Rayburn, who was also told by his jobcentre he would lose his benefits if he did not work without pay, said he spent almost two months stacking and cleaning shelves and sometimes doing night shifts.
(20) A growing educated middle class is losing touch with apartheid history and seeking alternatives.