(n.) Ill formation; irregular or anomalous formation; abnormal or wrong conformation or structure.
Example Sentences:
(1) The origin of the aorta and pulmonary artery from the right ventricle is a complicated and little studied congenital cardiac malformation.
(2) Cranial MRI revealed delayed myelination in the white matter but no brain malformation.
(3) These cases show that an examination of the whole neuraxis is as important in patients with midline posterior fossa cysts as it is in patients with developmental syringomyelia or Chiari I malformation.
(4) It was hypothesized that compensatory restraining influences of surrounding soft tissues prevented a more severe facial malformation from occurring.
(5) A neonate without external malformation had undergone removal of a nasopharyngeal mass containing anterior and posterior pituitary tissue.
(6) A retrospective study examined the reactions to the termination of pregnancy for fetal malformation and the follow up services that were available.
(7) We describe 10 patients with cerebral venous thrombosis: two had protein S deficiency, one had protein C deficiency, one was in early pregnancy, and there was a single case of each of the following: dural arteriovenous malformation, intracerebral arteriovenous malformation, bilateral glomus tumours, systemic lupus erythematosus, Wegener's granulomatosis, non-Hodgkin's lymphoma.
(8) It is usually associated with a left superior caval vein draining into the coronary sinus and is frequently part of a complex congenital malformation of the heart.
(9) The question addressed by this study is whether patients with other pharyngeal pouch malformations could also have immunologic abnormalities.
(10) The data of first 1000 first-born, non-malformed, mature (greater than or equal to 2500 g) offspring of participants in the Hungarian "Optimal" Family Planning Programme were evaluated.
(11) Nevertheless, the patterns of chromosomal abnormalities, and consequently that of associated malformations, were related to the different types of renal defects.
(12) Thirty-six lesions imaged as vascular malformations with abnormal vessels or diffusely increased activity.
(13) They constituted 7.3% of all patients with such malformations diagnosed during that period.
(14) Limb abnormalities included lumbar scoliosis, short malformed tibias and fibulas, and polydactyly.
(15) Bidrin treatment of quail embryos results in axial anomalies as well as malformations of the beak and the limbs.
(16) structural malformations, all congenital defects, and all disorders or abnormalities with possible prenatal etiology.
(17) The following examinations could be proposed: in high risk cases determined before pregnancy, a chorionic villus sampling should be done between the 9th and 11th weeks of gestation; in low risk cases such as advanced maternal age, a first trimester chorionic villus sampling or a second trimester amniocentesis could be chosen; in the case of Down's syndrome, warning signs, for example ultrasonographic or biological parameters, a second trimester placental biopsy to relieve the parents' anxiety; in high risk cases such as ultrasonographic malformations, late placental biopsy or cordocentesis.
(18) Orbital hypertelorism, strictly defined as an increase in bony interorbital distance, is not itself an isolated syndrome, but is instead an anomaly that may occur as either part of a syndrome or malformation sequence.
(19) The hand seemed almost normal in 3 cases but these cases seem to represent the variability of the malformation.
(20) There was no evidence for ocular trauma, disease, or vascular malformation by slit-lamp examination and gonioscopy.
Teratology
Definition:
(n.) That branch of biological science which treats of monstrosities, malformations, or deviations from the normal type of structure, either in plants or animals.
(n.) Affectation of sublimity; bombast.
Example Sentences:
(1) The importance of precocious development for planning teratological studies is emphasized.
(2) Unlike previous studies with 13-cis-retinoic acid during the pre- and early organogenic stages of development (Hummler et al., Teratology 42:263-272, 1990), no thymic hypo- or aplasia or heart anomalies were observed, which may be attributable to the slightly longer 13-cis retinoic acid treatment period, i.e., GD 10-27.
(3) It seems likely that diaphragmatic hernia is a non-specific consequence of several teratological processes.
(4) The principles of teratology are described, and animal models for research in abnormal ocular development and clinical studies of human teratogens are surveyed.
(5) Functional teratology is quite a new concept in neuroscience.
(6) Dams were killed on Day 19 and the fetuses were assessed for teratologic anomalies.
(7) On the basis of findings published in the literature, morphologic changes seen among the author's patients were classified as anthropologic and teratologic dislocations.
(8) The synthesis of these sciences into the relatively nascent science of reproductive toxicology includes teratology, pharmacology, epidemiology, and occupational and environmental health.
(9) In 1652, a chair of anatomy was created; embryology and teratology, at that time solely morphological sciences, depended on anatomy.
(10) No teratological or abortifacient effects were noted.
(11) The elaboration of the effect of retinoic acid on limb morphogenesis has prompted renewed investigation into the teratology of retinoic acid treatment, with the hope that such analysis might give insight into mechanisms of vertebrate patterning.
(12) The first generation (F0) gilts were bred after 4 months of study; some were killed for teratologic assays at 100 days of gestation (dg), and the others produced an F1 generation of offspring.
(13) The results are discussed with particular reference to the evaluation of teratologic studies on food colouring in general and the various regulation proposals from the National Food Administration.
(14) It also illustrates that selected histochemical studies may be helpful in a teratologic investigation.
(15) Subtle functional disturbances in organisms exposed while immature (behavioral teratology) may be one of the most sensitive indicators of chemical toxicity.
(16) N-Ethyl-N-nitrosourea (ENU) was administered intravenously to pregnant Wistar-albino rats on days 14--21 of gestation in order to study the teratological effects of the carcinogen on the developing brain.
(17) Concerning the applied doses no teratological effect was observed.
(18) The developmental toxicity of acetonitrile and 5 halogenated derivatives was examined with an in vivo teratology screen adapted for use in the Long-Evans rat.
(19) A wealth of literature has become available about lasting functional consequences of perinatal psychotropic drug exposure, having affected brain development in a subtle rather than gross structural way (behavioral teratology or functional neuroteratology).
(20) It is suggested that teratological investigations be carried out on the basis of a clearly formulated problem using experimental procedures suited to the biological characteristics of the test substances and of the animals.