(n.) Enmity of heart; malevolence; ill will; a spirit delighting in harm or misfortune to another; a disposition to injure another; a malignant design of evil.
(n.) Any wicked or mischievous intention of the mind; a depraved inclination to mischief; an intention to vex, annoy, or injure another person, or to do a wrongful act without just cause or cause or excuse; a wanton disregard of the rights or safety of others; willfulness.
(v. t.) To regard with extreme ill will.
Example Sentences:
(1) After addition of triiodothyronine, malic enzyme mRNA accumulated with sigmoidal kinetics, approaching a new steady state at 36-48 h after adding hormone.
(2) In addition to detecting three major antigenic variants of malic enzyme within this group, both antisera readily reacted with Streptococcus faecalis malic enzyme.
(3) The oxidative enzymes of the pentose phosphate pathway, ATP-citrate lyase, 'malic' enzyme and fatty acid synthetase also decrease markedly.
(4) Hormone therapy also caused an increase in the rate of incorporation of [3H]leucine into soluble proteins and in malic enzyme activity.
(5) Moreover, the transcriptional rate, mRNA concentration and induction of malic enzyme were increased by triiodothyronine treatment at a similar rate in both the young and old rats, but the absolute increments were lower in the old animals.
(6) The TRH treatment suppressed mitochondrial cytochrome c reductase and glucose-6-phosphatase activities, whereas cyclo(His-Pro) reduced cytochrome c reductase and malic enzyme activities.
(7) Activities of glucose-6-phosphate dehydrogenase and malic dehydrogenase of the mycelial form were higher than those of the yeast form.
(8) These observations suggest that in the rat neostriatum there are some neurons especially able to catabolize pyruvate via cytosolic malic isoenzyme.
(9) Thus a long-lived event in thyroid hormone stimulation of malic enzyme synthesis occurred prior to transcription of a specific messenger RNA (mRNA), presumably malic enzyme mRNA.
(10) In the Ob 17 preadipocyte cell line, during adipose differentiation, T3 amplified the progressive expression of two enzymes of the lipogenic pathway, ATP-citrate lyase (ATP-CL) and malic enzyme (ME) as previously described for fatty acid synthase (FAS) and fatty acid synthesis, and in the same time-period of development.
(11) The nucleotide sequence of the mRNA for malic enzyme ((S)-malate NADP+ oxidoreductase (oxaloacetate-decarboxylating, EC 1.1.1.40) from rat liver was determined from three overlapping cDNA clones.
(12) The specific nuclear binding of triiodothyronine (T3) (NBT3) and the activity of malic enzyme (ME), glucose-6-phosphate-dehydrogenase (G6PD), and 6-phosphogluconate-dehydrogenase (6PGD) were studied in the human fibroblast cell (MRC-5).
(13) 2-Hydroxyisobutyric acid, ethyl-2-hydroxybutyrate, malic acid, 1-butanol, benzyl alcohol and L-leucine did not act as substrates for the enzymes.
(14) Malic enzyme and glucose-6-phosphate dehydrogenase were highly active in the adipose tissue of mammals but were inactive in the adipose tissue of birds.
(15) Distribution of kinase activity in centrifugal fractions of both liver and heart mitochondrial sonicates was parallel to that of the two inner membrane marker enzymes succinic dehydrogenase and cytochrome oxidase and quite different from that of the matrix enzyme malic dehydrogenase.
(16) Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and malic enzyme are enzymes involved in NADPH synthesis.
(17) The antigenic enzymes, the precipitates of which are only stained by specific staining, are: aldolase, malic enzyme, acid phosphatase, peroxydase and cholinesterase.
(18) The coupling enzymes, fumarase (fumarate to L-malate) and malic enzyme (L-malate to pyruvate and NADPH), are adsorbed to nitrocellulose prior to blotting.
(19) The latter region apparently includes the malic dehydrogenase-1 gene.
(20) Some reactions, such as malic enzyme and glutamate dehydrogenase, may be inhibited or deleted with little or no adverse effect on the calculated cell growth rate.
Vice
Definition:
(n.) A defect; a fault; an error; a blemish; an imperfection; as, the vices of a political constitution; the vices of a horse.
(n.) A moral fault or failing; especially, immoral conduct or habit, as in the indulgence of degrading appetites; customary deviation in a single respect, or in general, from a right standard, implying a defect of natural character, or the result of training and habits; a harmful custom; immorality; depravity; wickedness; as, a life of vice; the vice of intemperance.
(n.) The buffoon of the old English moralities, or moral dramas, having the name sometimes of one vice, sometimes of another, or of Vice itself; -- called also Iniquity.
(n.) A kind of instrument for holding work, as in filing. Same as Vise.
(n.) A tool for drawing lead into cames, or flat grooved rods, for casements.
(n.) A gripe or grasp.
(v. t.) To hold or squeeze with a vice, or as if with a vice.
(prep.) In the place of; in the stead; as, A. B. was appointed postmaster vice C. D. resigned.
(prep.) Denoting one who in certain cases may assume the office or duties of a superior; designating an officer or an office that is second in rank or authority; as, vice president; vice agent; vice consul, etc.
Example Sentences:
(1) I am rooting hard for you.” Ronald Reagan simply told his former vice-president Bush: “Don’t let the turkeys get you down.” By 10.30am Michelle Obama and Melania Trump will join the outgoing and incoming presidents in a presidential limousine to drive to the Capitol.
(2) James Cameron, vice-chairman of Climate Change Capital , an environmental investment group, and a member of the prime minister's Business Advisory Group , says: "I think the UK has, in essence, become a better place for green investors.
(3) Chris Pavlou, former vice chairman of Laiki, told Channel 4 news that Anastasiades was given little option by the troika but to accept the draconian terms, which force savers to take a hit for the first time in the fifth bailout of a eurozone country.
(4) Grace has no capacity so she will be very mechanised.” This week Robert Mugabe described Mujuru, his vice-president of a decade, as too simplistic .
(5) La3+ binding was partially inhibited by RuR and vice versa, and La3+ was also capable of partially displacing RuR previously bound to the synaptosomes, particularly in the sucrose medium.
(6) It is not known whether the conversion of DHEAS into E1 and E2 influence the conversion of 16OH-DHEAS into E3 and vice versa.
(7) Behavioral interventions developed for alcohol abuse are now being tested with drug abusers, and vice versa.
(8) George Bush, who won Ohio narrowly last time, has been there almost 20 times in the past four years and Vice-President Cheney is on his way this week.
(9) And I was a little surprised because I said: ‘Doesn’t sound like he did anything wrong there.’ But he did something wrong with respect to the vice-president and I thought that was not acceptable.” So that’s clear.
(10) The vice chancellor of the Catholic University, Greg Craven, wrote in the Australian that stripping either dual or sole nationals of citizenship via a ministerial decision “would be irredeemably unconstitutional.
(11) The only thing Michael Fabricant could reasonably be vice-chairman of is the steering committee of Nurse Ratched 's ward fete.
(12) With this announcement, the UK is demonstrating the type of leadership that nations around the world must take in order to craft a successful agreement in Paris and solve the climate crisis,” said former US vice-president Al Gore.
(13) "This was followed later by an attack at the SPLA (South Sudan army) headquarters near Juba University by a group of soldiers allied to the former vice-president Dr Riek Machar and his group.
(14) Norepinephrine (10(-5) to 10(-6) M) increased contractile force and decreased alpha iNa, but in its presence ACh still increased force and alpha iNa and vice versa.
(15) Microbial antigen-specific LTT responses fluctuated considerably in time from strongly positive to negative and vice versa in healthy individuals as well as in patients.
(16) Lynn Kramer, the zoo's vice-president of animal operations and welfare, said five lions were typically in the exhibit and have never appeared to endanger each other before.
(17) Retrieval was manipulated by representing a proportion of the old picture and word items in their opposite form during the recognition test (i.e., some old pictures were tested with their corresponding words and vice versa).
(18) Any family seen to be "enmeshed" is also seen as "fused," and vice versa.
(19) During flexion the lateral femoral condyle displays near extension pure rolling, near flexion pure gliding, on the medial side this ratio is vice versa.
(20) Vice versa, when the glpF and glpK(+) alleles of S. flexneri are incorporated into E. coli, the hybrid strain grows slowly in low glycerol medium.