What's the difference between mechanism and pathogenesis?

Mechanism


Definition:

  • (n.) The arrangement or relation of the parts of a machine; the parts of a machine, taken collectively; the arrangement or relation of the parts of anything as adapted to produce an effect; as, the mechanism of a watch; the mechanism of a sewing machine; the mechanism of a seed pod.
  • (n.) Mechanical operation or action.
  • (n.) An ideal machine; a combination of movable bodies constituting a machine, but considered only with regard to relative movements.

Example Sentences:

  • (1) Such a signal must be due to a small ferromagnetic crystal formed when the nerve is subjected to pressure, such as that due to mechanical injury.
  • (2) These data suggest that the hybrid is formed by the same mechanism in the absence and presence of the urea step.
  • (3) Some common eye movement deficits, and concepts such as 'the neural integrator' and the 'velocity storage mechanism', for which anatomical substrates are still sought, are introduced.
  • (4) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
  • (5) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
  • (6) It is concluded that amlodipine reduces myocardial ischemic injury by mechanism(s) that may involve a reduction in myocardial oxygen demand as well as by positively influencing transmembrane Ca2+ fluxes during ischemia and reperfusion.
  • (7) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.
  • (8) The following is a brief review of the history, mechanism of action, and potential adverse effects of neuromuscular blockers.
  • (9) However, the mechanism of the inhibitory action is still somewhat uncertain.
  • (10) It also provides mechanical support for the collateral ligaments during valgus or varus stress of the knee.
  • (11) We studied the hemodynamic changes caused by bronchoscopy under LA in mechanically ventilated patients and the effect of LA on the endoscopic decline in arterial pO2.
  • (12) Together these observations suggest that cytotactin is an endogenous cell surface modulatory protein and provide a possible mechanism whereby cytotactin may contribute to pattern formation during development, regeneration, tumorigenesis, and wound healing.
  • (13) Dilutional studies comparing the mechanism of inhibition of monoamine oxidase produced by Gerovital H3 and by ipronizid demonstrated that Gerovital H3 was a reversible inhibitor of monoamine oxidase.
  • (14) To investigate the mechanism of enhanced responsiveness of cholesterol-enriched human platelets, we compared stimulation by surface-membrane-receptor (thrombin) and post-receptor (AlF4-) G-protein-directed pathways.
  • (15) Based on our results, we propose the following hypotheses for the neurochemical mechanisms of motion sickness: (1) the histaminergic neuron system is involved in the signs and symptoms of motion sickness, including vomiting; (2) the acetylcholinergic neuron system is involved in the processes of habituation to motion sickness, including neural store mechanisms; and (3) the catecholaminergic neuron system in the brain stem is not related to the development of motion sickness.
  • (16) Thus, mechanical restitution of the ventricle is a dynamic process that can be assessed using an elastance-based approach in the in situ heart.
  • (17) The mechanism by which pertussis toxin (PT) breaks the unresponsiveness of delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC) was examined in B10 mice.
  • (18) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
  • (19) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
  • (20) Adding a layer of private pensions, it was thought, does not involve Government mechanisms and keeps the money in the private sector.

Pathogenesis


Definition:

  • (n.) Pathogeny.

Example Sentences:

  • (1) The combined analysis of pathogenesis and genetics associated with the salmonella virulence plasmids may identify new systems of bacterial virulence and the genetic basis for this virulence.
  • (2) Although antihistamines are widely used for symptomatic treatment of seasonal (allergic) rhinitis, the role of histamines in the pathogenesis of infectious rhinitis is not clear.
  • (3) In concert with TF expressed by monocytes and macrophages this endothelial cell procoagulant activity may play a role in the pathogenesis of thrombotic disease.
  • (4) Escherichia enterotoxigenic strains, Yersinia enterocolitica and Salmonella typhimurium virulent strains, Campylobacter jejuni clinical isolates possess more pronounced capacity for adhesion to enteric cells of Peyer's plaques than to other types of epithelial cells, which may be of importance in the pathogenesis of these infections.
  • (5) Functional as well as mechanical factors may be important in the pathogenesis of cholestatic syndromes.
  • (6) Its pathogenesis, still incompletely elucidated, involves the precipitation of immune complexes in the walls of the all vessels.
  • (7) The authors describe the role played by these substances in the pathogenesis of inflammations, their importance in the regulation of intraocular pressure and in the development of cystoid macular oedema.
  • (8) With the aim of evaluating the role of 1,25 dihydroxyvitamin D in the pathogenesis of osteoporosis, this hormone was studied in 90 subjects.
  • (9) The findings suggest that mast cell prostaglandins are an important factor in the pathogenesis of pruritus and that local vascular responses may trigger mast cell degranulation.
  • (10) The development of pulmonary edema in high-altitude residents with upper respiratory infections and no antecedent low-altitude journey is consistent with the presence of other factors such as inflammation, which may play a role in the pathogenesis of the edema.
  • (11) Although not common, the disorder is the most frequently diagnosed disturbance of porphyrin metabolism in many countries, and further insight into its unusual pathogenesis may clarify the hepatotoxic effects of the 4 etiologic agents.
  • (12) Proliferation of untransformed FDC-PI cells and the emergence of variants with improved adaptation to in vivo conditions appear to be important and possibly necessary steps in the pathogenesis of the disease.
  • (13) These results may suggest that liver subcellular component is involved in pathogenesis of drug-induced allergic hepatitis.
  • (14) Our findings suggest that the affinity of aldose reductase for glucose in patients with diabetic complications may be increased and that the polyol pathway is implicated in the pathogenesis of diabetic complications.
  • (15) Pathogenesis of acute osteomyelitis is analyzed from the standpoint of disorders in the bone microcirculation.
  • (16) Taken together with recent data from transgenic animals, this in vitro observation has possible implications for our view of the pathogenesis of pancreatic neoplasia.
  • (17) In the discussion, some of the theories of the pathogenesis of clubbing are reviewed, together with previous reports of clubbing in gastro-oesophageal disorders.
  • (18) Antigenic mimicry by T. cruzi antigens sharing epitopes with host macromolecules has been implicated in the pathogenesis which is thought to have a significant autoimmune component.
  • (19) Further studies are required to show whether these differences are real and, if so, whether they have any relevance for the pathogenesis of migraine attacks.
  • (20) The evidence suggests that this isozyme is not necessary for soft-rot pathogenesis.