(n.) One who mediates; especially, one who interposes between parties at variance for the purpose of reconciling them; hence, an intercessor.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
(14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
(15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(18) injection of various inflammatory mediators, the vasopressor effect of i.a.
(19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
(20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.
Mutual
Definition:
(a.) Reciprocally acting or related; reciprocally receiving and giving; reciprocally given and received; reciprocal; interchanged; as, a mutual love, advantage, assistance, aversion, etc.
(a.) Possessed, experienced, or done by two or more persons or things at the same time; common; joint; as, mutual happiness; a mutual effort.
Example Sentences:
(1) In Tirana, Francis lauded the mutual respect and trust between Muslims, Catholics and Orthodox Christians in Albania as a "precious gift" and a powerful symbol in today's world.
(2) The aortic area (Torlin) for diseased stenotic aortic valves was calculated in 10 patients using two different methods; data obtained in preoperative cardiac catheterization and by intraoperative flowmetric and aortic and left ventricular pressure-recording measurements, and their mutual correlation was tested.
(3) This "gender identity movement" has brought together such unlikely collaborators as surgeons, endocrinologists, psychologists, psychiatrists, gynecologists, and research specialists into a mutually rewarding arena.
(4) There was a mutually reversible interaction between bicuculline and intrathecal administration of the GABAA agonist, muscimol (8.8 nmol), which alone decreased arterial pressure and heart rate.
(5) The significance of the present findings on the mutual suppression of metabolism between benzene and toluene is discussed in relation to solvent toxicology and biological monitoring of exposure to the solvents.
(6) However, it should be stressed that none of these mechanisms is mutually exclusive; indeed, the enormous complexity of tumor promotion suggests that several of the mechanisms discussed above may very well be interrelated.
(7) In 254 findings of the acid-base balance ions and proteins, the authors evaluated mutual relations between the acid-base balance and calculation from the anion column.
(8) There is a mutual interest in keeping prosperity that exists and has built over the years.” But Pisani-Ferry said Macron would certainly not seek to punish Britain.
(9) Great morphological variability of Apiosoma is reflected in variability of shape and size of the body and mutual arrangement of micro--and macronucleus.
(10) Bostock, who is long thought to have had a tense relationship with chief executive Marc Bolland , is departing by "mutual consent to pursue other interests" on 1 October, when she will also leave the M&S board.
(11) As Aesop reminds us at the end of the fable: “Nobody believes a liar, even when he’s telling the truth.” When leaders choose only the facts that suit them, people don’t stop believing in facts – they stop believing in leaders This distrust is both mutual and longstanding, prompting two clear trends in British electoral politics.
(12) According to informal private communications, a new joint recommendation on RFR ELs for all countries belonging to the Council of Mutual Economic Cooperation (COMECON) is being developed.
(13) Plasmin and elastase may play mutual roles in thrombolysis, inflammation, and tumour invasion and metastasis.
(14) A simple equilibrium method for detecting and quantifying these interactions is to study the mutual influence of the molecules on their respective counter-current distribution in liquid-liquid biphasic systems.
(15) A cell fractionation procedure is described which allowed, by use of MOPC 21 (P3K) mouse plasmocytoma cells in culture, the separation of the cytoplasmic free and membrane-bound ribosomes in fractions devoid of mutual cross-contamination, and in which the polyribosomal structure was entirely preserved.
(16) In The Girl, the relationship moves from Pygmalion to Beauty and the Beast, before curdling into something more mutually destructive, if not downright abusive.
(17) "Building societies and other mutual lenders continue to play a dominant role in supporting members of the UK public looking to buy a new home," said Paul Broadhead, head of mortgage policy at the BSA.
(18) The 140-year-old mutual, the UK's 12th largest building society, will confirm that it lost £26m last year after risky investments in the property market.
(19) It’s called freedom.” 4.25pm GMT Nato has released a statement of solidarity following its meeting called by Poland under Article 4 of the Washington Treaty providing for mutual consultation and support.
(20) As the Labour leadership accused the coalition of launching a smear campaign over the party's links with the disgraced chairman, a transcript of an interview with Balls in 2010 showed that he highlighted his role in helped to create Britain's "first ever 'super-mutual'".