(1) The quinolinate synthetase B protein exists in all nadA and nadC mutants examined.
(2) The presence of cAMP + cAMP receptor protein was essential for the complete derepression of nadA while no effect was evident upon nadB.
(3) She alleged that Epstein went on to make her have sex with Nada Marcinkova, another female Epstein associate .
(4) The structure of the adducts is in conformity with the generation and reactions of dehydro NADA quinone methide (or its radical).
(5) Accordingly, desaturase enzyme preparation contained both o-diphenoloxidase activity and NADA quinone:NADA quinone methide isomerase activity.
(6) Resolution of the NADA desaturase system on Benzamidine Sepharose and Sephacryl S-200 columns yielded the above-mentioned quinone isomerase and NADA quinone methide:dehydro NADA isomerase.
(7) The present paper reports on the mechanism by which dehydro-NADA is oxidatively activated to form reactive intermediate(s) as revealed by pulse radiolysis, electron spin resonance spectroscopy, high performance liquid chromatography, and ultraviolet-visible spectroscopic analysis.
(8) Exogenously added NADA quinone was readily converted by these enzyme preparations to N-acetylnorepinephrine and dehydro NADA.
(9) High-copy-number vectors, carrying either gene nadA, nadB or nadA + nadB, increased quinolinate production 1.5-fold, 2.0-fold and 15-fold respectively.
(10) After ecdysis NADA became the major hemolymph catecholamine in all species as DA decreased rapidly.
(11) The NADA desaturase system which converts NADA to 1,2-dehydro-NADA, surprisingly, does not resemble dehydrogenases such as succinate dehydrogenase.
(12) NADA-sulphate was quantified by an HPLC-ECD method while the decrease in 4-MU was monitored continuously by a fluorimetric procedure.
(13) These studies indicate that NADA quinone is an intermediate during the side chain hydroxylation of NADA by Manduca cuticular enzyme(s).
(14) The remaining nicotinamide mononucleotide accumulates extracellularly and will support the growth of nadA pncB mutants which cannot utilize the nicotinamide resulting from the major pathway of NAD degradation.
(15) In addition, the sulfate conjugate formed, namely N-acetyldopamine-sulfate (NADA-sulfate) was quantified directly by high-pressure liquid chromatography cum electrochemical detection (HPLC-ECD).
(16) Kinetic studies with NADA showed two pH optima of 6.7 and 8.6 for the overall sulphate conjugation and the PST reaction while the PAPS generation occurred maximally at pH 8.0.
(17) Reconstitution of NADA side chain desaturase activity was achieved by mixing the last enzyme fraction with NADA quinone isomerase, obtained from the hemolymph of the same organism, and mushroom tyrosinase.
(18) Evidence for the formation of an unstable intermediate in the synthesis of quinolinate from aspartate and dihydroxyacetone phosphate by Escherichia coli was obtained using toluenized cells of nadA and nadB mutants of this organism and partially purified A and B proteins in dialysis and membrane cone experiments.
(19) Media coverage was, not surprisingly, sparse – one interview for Melody Maker is vague to the point of rendering itself totally “nada”, while an Island press release is something of a bad joke.
(20) Confirmation of the operon arrangement for nadA and pnuC was obtained through the sequence analysis of a 2.4-kilobase DNA fragment which complemented both NadA and PnuC mutant phenotypes.
Nothing
Definition:
(n.) Not anything; no thing (in the widest sense of the word thing); -- opposed to anything and something.
(n.) Nonexistence; nonentity; absence of being; nihility; nothingness.
(n.) A thing of no account, value, or note; something irrelevant and impertinent; something of comparative unimportance; utter insignificance; a trifle.
(n.) A cipher; naught.
(adv.) In no degree; not at all; in no wise.
Example Sentences:
(1) "We examined the reachability of social networking sites from our measurement infrastructure within Turkey, and found nothing unusual.
(2) Northern Ireland will not be dragged back by terrorists who have nothing but misery to offer."
(3) But becoming that person in a traditional society can be nothing short of social suicide.
(4) But what they take for a witticism might very well be true; most of Ellis's novels tell more or less the same story, about the same alienated ennui, and maybe they really are nothing more than the fictionalised diaries of an unremarkably unhappy man.
(5) Almost nothing is known about nature and timing of the embryonic cues which induce or initiate spicule formation by these cells.
(6) If Queensland goes ahead and develops and dredges Abbot Point, it may all be for nothing.
(7) Meanwhile the Brooklyn Nets, who have been dealing with nothing but bad news since the start of the regular season, will be without Paul Pierce for 2-4 weeks, also due to a right hand fracture.
(8) After violence had run its bloody course, the country’s rulers conceded it had been a catastrophe that had brought nothing but “grave disorder, damage and retrogression”.
(9) But there was a clear penalty on Diego Costa – it is a waste of time and money to have officials by the side of the goal because normally they do nothing – and David Luiz’s elbow I didn’t see, I confess.
(10) The three-year-old comes into the kitchen for a drink, and as Steve opens the fridge, I can see it contains nothing apart from a half-full bottle of milk.
(11) It’s the same story over and over.” Children’s author Philip Ardagh , who told the room he once worked as an “unprofessional librarian” in Lewisham, said: “Closing down a library is like filing off the end of a swordfish’s nose: pointless.” 'Speak up before there's nothing left': authors rally for National Libraries Day Read more “Today proves that support for public libraries comes from all walks of life and it’s not rocket science to work out why.
(12) She is not: "Religion has nothing to do with spirituality."
(13) The prime minister said: “I am taking absolutely nothing for granted.
(14) We always feel like it's Hobbitshire – a green valley where nothing happens."
(15) She says he wants his actors to be in a "second state", instinctive, holding nothing back.
(16) As for gay men, there is absolutely nothing that suggests they are any less war-happy than heterosexuals.
(17) Like Morton, Sevigny is an actor who holds nothing back from the camera.
(18) Answer, citing Edmund Burke: “The only thing necessary for the triumph of evil is for good men to do nothing.” This is a very British suicide.
(19) I’d argue, furthermore, that these preoccupations are preventing people from seeking support, as if nothing could be more the opposite of these things than admission of the need for help.
(20) Lion cubs fathered by Cecil, the celebrated lion shot dead in Zimbabwe , may already have been killed by a rival male lion and even if they were still alive there was nothing conservationists could do to protect them, a conservation charity has warned.