(n.) That point of the heavens, or lower hemisphere, directly opposite the zenith; the inferior pole of the horizon; the point of the celestial sphere directly under the place where we stand.
(n.) The lowest point; the time of greatest depression.
Example Sentences:
(1) Following parturition, NONLAC cows averaged 4.0 d to negative EB nadir and 14.3 d to first ovulation.
(2) Seven days of constant light, however, reverses this diurnal variation such that plasma prolactin levels peak at 11:30 AM and reach a nadir at approximately 11:30 PM.
(3) Microsomal protein synthesis as measured by [3H]leucine incorporation was also depressed in a dose-dependent fashion; however, inhibition did not reach the nadir until day 4, 1 day after renal dysfunction was established.
(4) A trend to a phase-advance of cortisol nadir and melatonin peak was seen in the acutely ill depressed patients with abnormal DST, possibly indicating an involvement of the suprachiasmatic nuclei in the hypothalamus.
(5) The time-related incidence of these cells entities--the appearance of "dusk" and "bright" cells at 5 min, transitory domination of "bright" cells and the nadir of "dusk" cells at 20 min, sporadic recognition of "bright" cells, lack of "dusk" cells at 45 min and the absence of both cell forms at 180 min--displayed that LP-reactive response promptly appeared and rapidly ceased.
(6) In women, but not in men, there was a rise in the risk of falling from 45 years, peaking in the 55-59 year age group, and sinking to a nadir at ages 70-74.
(7) The binding is highest in the early morning and reaches a nadir in the late afternoon.
(8) Strict criteria for dose adjustments according to nadir counts were applied.
(9) One became azoospermic at week 16, while the other's total sperm counts continued declining and reached a nadir of 1.4 million by week 20.
(10) The WBC nadir occurred at a median of 10 days and the median time required for normalization of the WBC was 18 days.
(11) The main toxicity was haematological with delayed leucopenia and thrombopenia (nadir: week 6).
(12) Nadir values coincided with maximal toxic granulation of the neutrophils.
(13) The circadian rhythm observed in patients with intermittent claudication has early evening peaks and a nocturnal trough with a nadir occurring after midnight and before 0400.
(14) Portsmouth , still looking for their first home win under Tony Adams, dominated the first 25 minutes, when Nadir Belhadj was outstanding.
(15) Pre-treatment concentrations of P-FN were within the reference range and significantly higher than the nadir value (p less than 0.05).
(16) A model was constructed according to these two parameters that significantly describes ln (nadir WBC) (p = 0.001).
(17) Following spontaneous horizontal roving eye movement, both eyes deviated downward slowly from midposition, taking 1 to 2 seconds to reach the nadir.
(18) Griffiths replaced Nadir Ciftci for the start of the second half after a dismal first 45 minutes from the home side and Ronny Deila’s men continued to struggle, with Bitton sent off in the 67th minute after picking up his second yellow card.
(19) The second pulse was of slightly lower amplitude, reaching a maximum of 2.3 to 8.0 fold over the control value and 1.25 to 2.5 fold over the preceding nadir.
(20) The period from 2004-5 was the nadir: some American DJs even emigrated to Berlin, where the work prospects were better.
Zenith
Definition:
(n.) That point in the visible celestial hemisphere which is vertical to the spectator; the point of the heavens directly overhead; -- opposed to nadir.
(n.) hence, figuratively, the point of culmination; the greatest height; the height of success or prosperity.
Example Sentences:
(1) The Cambridge-based couple felt ignored when tried to raise the alarm about the way their business – publisher Zenith – was treated by Lynden Scourfield, the former HBOS banker jailed last week, and David Mills’ Quayside Corporate Services.
(2) After 24 h of fasting the zenith was shifted to the beginning of dark period without any other changes.
(3) Clinical electroencephalography, which reached a zenith in the 1950s and 1960s, increased the range of diagnostic techniques available for a series of brain diseases and revolutionized the study of epilepsy.
(4) That triumphal speech was his apex, the acme, the zenith of his career.
(5) The circadian rhythm of PRL persisted throughout lactation as manifested by: (1) significantly higher mean nighttime than daytime PRL levels in the whole sample, despite higher daytime nursing durations; (2) the distribution of zenith levels which most frequently occur between 23.00 and 07.00 h, when nursing duration is lowest, and which are almost absent between 07.00 and 23.00 h, when nursing duration is highest, and of nadir levels, which have an opposite pattern; (3) spontaneous PRL surges that are more frequent, longer, and of higher magnitude at night than during the day, and (4) the larger magnitude of suckling-induced PRL release from late afternoon through the night compared to the morning in some women.
(6) The zeniths of the curves were recorded about 4--6 hours after the skin incision in both patient groups, despite the different duration of the operations.
(7) However, 1990 proved to be not only the Indy's circulation zenith but also a watershed for its publishing company as recession bit hard into revenue.
(8) After 48 h of fasting remarkable shifts were found resulting in a nadir at the beginning of dark period and a zenith at the middle of light period.
(9) The dying have much to teach the living: so in many ways, this project is the zenith of the Big Brother experiment.
(10) The kind of cinema that reached a zenith in Gillo Pontecorvo's Battle of Algiers .
(11) The cercal system, which may have evolved with the first terrestrial hexapods, reaches its zenith in the orthopteroid insects, but was replaced in holometabolan insects by visual startle mechanisms with descending giant interneurons.
(12) Population growth reached its zenith between 1950-70.
(13) We detected a consistent and significant (P less than 0.01) decline in plasma chromium after glucose administration, the nadir of the chromium response coinciding with the zenith of the glucose concentration.
(14) Thus, the ED30s constitute the "zenith" of an independent isobole in ED50 isobolograms.
(15) They reached a zenith during the Vietnam war when the US government allegedly conducted their highly classified Operation Popeye, an attempt to extend the monsoon season by cloud seeding in the hope of flushing out the Viet Cong.
(16) On Sunday, Mélenchon's star reached its zenith, when early results gave him 11.1% of votes, several percentage points lower than had been expected.
(17) Whereas phosphate has a marked circadian rhythmicity with a zenith between 1.00 and 8.00 hours, total calcium and albumin show a tendency to decrease between 20.00 and 6.00 hours.
(18) The zenith of suppressor activity was observed during most active infection, from 1 to 3 weeks after inoculation.
(19) At the zenith of a culture war, there’s seldom room for compromise.
(20) The highest pressures in the series (about 4 to 5 megaNewtons per square metre) were on the areas of thin fibrocartilage which were identified at the zenith of certain acetabula.