(1) Neonatal alloimmune thrombocytopenic purpura (NAITP) is induced by maternal antibodies to fetal platelet alloantigens.
(2) They review the platelet antigen systems involved in NAITP and raise the problem of its present antenatal and postnatal management.
(3) This antigen is considered to be a product of an allele of the Yuk gene, another allele of which codes for Yuka which was involved in 2 cases of NAITP.
(4) anti-HLA-A24+B51 and anti-HLA-Bw61+Cw3, respectively, were detected in the mother's sera, which reacted to each patient's lymphocytes and were presumed to have been contribute to NAITP.
(5) Antibodies to the platelet HPA-1a antigen can elicit in the newborn a condition known as neonatal alloimmune thrombocytopenic purpura (NAITP).
(6) The case report emphasises that in patients with NAITP intracranial haemorrhage may occur in utero and during the perinatal period as well.
(7) Furthermore, in a review from the currently available literature the following items will be discussed: 1) human platelet antigens involved in NAITP, 2) clinical aspects and prognosis of NAITP, 3) immunological diagnosis of NAITP, and 4) prevention and treatment of the disease.
(8) We propose further study to determine if this is specific for the antepartum diagnosis of NAITP.
(9) Here reported are two cases with neonatal alloimmune thrombocytopenia (NAITP).
(10) However, the strongest association both in mothers of NAITP patients and in PTP patients was observed with the supertypic DRw52 antigen.
(11) On the other hand, some NAITP cases may have been overlooked because of their mildness.
(12) The only mother who was delivered of a child with clinical NAITP was the woman with anti-Zwa(PIA1) in serum.
(13) Sensitive assays of maternal platelet alloantibody are now available, but they lack specificity for NAITP affecting the current gestation.
(14) The authors report a case of two siblings who developed a neonatal alloimmune thrombocytopenia (NAITP) due to Bak-System incompatibility.
(15) We report a new platelet antigen (Yukb) involved in a case of neonatal alloimmune thrombocytopenia (NAITP).
(16) We demonstrate the sonographic and computer-tomographic findings in a newborn with neonatal alloimmune thrombocytopenia (NAITP).
(17) The strong association between HLA-DR3 and Zwa alloimmunization in Zwa-negative mothers, resulting in the production of anti-Zwa antibodies and ultimately in neonatal alloimmune thrombocytopenic purpura (NAITP) in the newborn, could be confirmed.
(18) We reviewed 58 literature reports of neonatal alloimmune thrombocytopenic purpura (NAITP).
Neonatal
Definition:
Example Sentences:
(1) After 55 days of unrestricted food availability the body weight of the neonatally deprived rats was approximately 15% lower than that of the controls.
(2) Most thyroid hormone actions, however, appear in the perinatal period, and infants with thyroid agenesis appear normal at birth and develop normally with prompt neonatal diagnosis and treatment.
(3) The clinical usefulness of neonatal narcotic abstinence scales is reviewed, with special reference to their application in treatment.
(4) A review of campylobacter meningitis by Lee et al in 1985 reported nine cases occurring in neonates, of which only one case was caused by C. fetus.
(5) A neonate without external malformation had undergone removal of a nasopharyngeal mass containing anterior and posterior pituitary tissue.
(6) In a random sample of 1,000 neonates from a Delhi Hospital the incidence of jaundice was 53% and of hyperbilirubinaemia (HB) 6%.
(7) It was found that preterm infants (delivered before 38 weeks of gestation) had nine times the early neonatal mortality of term infants, irrespective of growth retardation patterns.
(8) A reduction in neonatal deaths from this cause might be expected if facilities for antenatal diagnosis and termination of pregnancy were made available, although this raises grave ethical problems.
(9) A patient previously reported to have discoid lupus erythematosus as a neonate eventually developed systemic lupus erythematosus (SLE) at age 19 years.
(10) Neonatal data included birthweight and gestational age.
(11) There are no published reports of its detection in neonates born to affected mothers.
(12) N-Acetyl-beta-D-glucosaminidase (GAD) activities did not change significantly duringlate fetal, neonatal or young adult stages but increased significantly with advancing age.
(13) Striated muscle fibres were found in each of twenty consecutive pineal glands cultured from individual neonatal rats.2.
(14) Confirmation of the striking correlation between increased urinary ammonia and lowered neonatal ponderal index may afford a simple test for the identification of nutrient-related growth retardation.
(15) There were 4 spontaneous first trimester abortions and 21 live-born neonates without major problems related to the treatment or to the maternal disease.
(16) Neonatal treatment with a low dose of the estrogen diethylstilbestrol (DES) had no significant effect on adult estrogen binding within the assayed vaginal compartments; however, this treatment caused a 2-fold increase in the level of cytosolic progestin binding in the vaginal FMW over that in vehicle-treated mice.
(17) Governmental officials as well as medical scientists in Taiwan have worked hard in recent years to develop and to implement various measures, such as prenatal diagnosis and neonatal screening, to lower the incidence of hereditary diseases and mental retardation in the population.
(18) Histological studies with neonatal mice raise the possibility that Müllerian duct tissue may represent a site for the transplacental toxicity of DES in both the male and female fetus.
(19) Extrapolating animal data to the neonates, we found the thoracic segment length recommended (the average of 29% of body length and electrode distance) to be accurate.
(20) These data indicate improved bone mineralization as compared with previously reported data from very-low-birth-weight neonates.