(a.) Having the properties of a narcotic; operating as a narcotic.
(n.) A drug which, in medicinal doses, generally allays morbid susceptibility, relieves pain, and produces sleep; but which, in poisonous doses, produces stupor, coma, or convulsions, and, when given in sufficient quantity, causes death. The best examples are opium (with morphine), belladonna (with atropine), and conium.
Example Sentences:
(1) The clinical usefulness of neonatal narcotic abstinence scales is reviewed, with special reference to their application in treatment.
(2) Recent research conducted by independent investigators concerning the relationship between crime and narcotic (primarily heroin) addiction has revealed a remarkable degree of consistency of findings across studies.
(3) The interactions of 3 classical alpha-adrenergic antihypertensives of prevalently central type (St 155 or clonidine St 600; BR 750 or guanabenz) with the narcotic effects of pentobarbital have been investigated in the Mus musculus.
(4) We studied the arterial blood gas determinations done on the first hospital day in 14 narcotic addicts with bacterial endocarditis (group 1) and six addicts with other medical complications of narcotic addiction (group 2).
(5) The prostaglandins A1, E1, A2, E2 and F2a were comparatively studied for their antiarrhythmic action using the model of strophanthin arrhythmia of narcotized cats.
(6) Postoperative nausea and vomiting have been associated with the use of intravenous narcotics, and nitrous oxide may worsen the emetic effects of narcotics.
(7) Though intraspinal narcotic analgesia is associated with a number of side effects, with proper knowledge these adverse reactions are wither preventable or can be greatly reduced.
(8) In this open study we reviewed the circadian distribution of extra doses of narcotic analgesics in 61 bed-ridden patients with cancer pain.
(9) In narcotized cats different respiratory reactions in acute myocardial ischemia was estimated with complicated and non-complicated ventricular fibrillation.
(10) Infants prenatally exposed to narcotics become passively addicted in-utero and may undergo neonatal abstinence at birth.
(11) Convergent results from a multimethod assessment of the issue show that methadone maintenance has long-term and short-term suppressive effects on narcotics use and property crime.
(12) The pharmacokinetics of the narcotic analgesic dextromoramide was investigated by means of a specific GC-MS method in 9 patients who were given a single oral dose of the drug (7.5 mg) together with an anticholinergic before undergoing minor orthopedic surgery.
(13) Ethanol-withdrawn animals displayed an increased sensitivity to the narcotic action of toluene.
(14) Their addiction at the time of seeking treatment was well established: narcotic drugs comprised their main daily expenditure, they had numerous problems associated with narcotic use, and high doses of methadone were necessary for detoxification.
(15) These results provide further evidence that narcotic-induced respiratory depression and analgesia are mediated by different receptor interactions.
(16) Hypericum extract enhanced the exploratory activity of mice in a foreign environment, significantly prolonged the narcotic sleeping time dose-dependently, and within a narrow dose range exhibited reserpine antagonism.
(17) In summary, there are now available very potent narcotics, with small side effect liability.
(18) This paper analyses the influence of medical professional organization on the formation of attitudes and policies toward narcotics in England.
(19) Most involved children less than 3 (42%) yr or greater than 12 (33%) yr. Products most commonly ingested included tricyclic antidepressants (22%), benzodiazepines (15%), theophylline (10%), ethanol (10%), hallucinogens (8%), salicylates (8%), narcotics (8%), antihistamines (7%), and carbamazepine (5%).
(20) In this respect the narcotic antagonist effects resemble those produced by the antiserotonin compounds or opiate agonists.
Sleep
Definition:
() imp. of Sleep. Slept.
(v. i.) To take rest by a suspension of the voluntary exercise of the powers of the body and mind, and an apathy of the organs of sense; to slumber.
(v. i.) To be careless, inattentive, or uncouncerned; not to be vigilant; to live thoughtlessly.
(v. i.) To be dead; to lie in the grave.
(v. i.) To be, or appear to be, in repose; to be quiet; to be unemployed, unused, or unagitated; to rest; to lie dormant; as, a question sleeps for the present; the law sleeps.
(v. t.) To be slumbering in; -- followed by a cognate object; as, to sleep a dreamless sleep.
(v. t.) To give sleep to; to furnish with accomodations for sleeping; to lodge.
(v. i.) A natural and healthy, but temporary and periodical, suspension of the functions of the organs of sense, as well as of those of the voluntary and rational soul; that state of the animal in which there is a lessened acuteness of sensory perception, a confusion of ideas, and a loss of mental control, followed by a more or less unconscious state.
Example Sentences:
(1) AEDs may also have differential effects on nighttime sleep.
(2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(3) For assessment of clinical status, investigators must rely on the use of standardized instruments for patient self-reporting of fatigue, mood disturbance, functional status, sleep disorder, global well-being, and pain.
(4) We investigated whether these peptides also affect the sleep EEG in humans when given intravenously by comparing polysomnographically the effects of four boluses of (1) placebo, (2) 50 micrograms GHRH or (3) 50 micrograms SRIF administered at 22.00, 23.00, 24.00 and 1.00 h to 7 male controls.
(5) Polygraphic recordings during sleep were performed on 18 elderly persons (age range: 64-100 years).
(6) This was carried out on the healthy subjects for a total of 12 nights without medication (control nights asleep), a total of 12 nights following 40 mg of flucortolone the previous morning, and a total of 6 nights with similar blood sampling when sleep was prevented (control nights awake).
(7) Although temazepam was effective for maintaining sleep with short-term use, there was rapid development of tolerance for this effect with intermediate-term use.
(8) The occurrence of episodes of desaturation during sleep in patients suffering from chronic airflow obstruction is well known.
(9) A lower than normal percentage of REM sleep in these patients was consistent with their retarded intellectual development, which supports current thinking that REM sleep may be a sensitive index of brain function integrity.
(10) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(11) Results of sleep sampling under electroencephalographic control of the assessment of GH secretion are comparable to conventional pharmacological studies in terms of efficiency, sensitivity, and percentage false-negatives.
(12) Sleep was defined behaviorally as failure to respond to the faint auditory RT cue.
(13) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(14) However, patients can be taught how to retard the onset of wrinkles by avoiding unprotected sun exposure, unnecessary facial movements, and certain sleeping positions.
(15) The analogy with infant sleep patterns and results of studies of brain function in narcoleptics suggest that forebrain inhibitory processes are more important in narcoleptic symptomology than is brainstem dysfunction.
(16) In short term clinical studies, the beneficial effects of transdermal estradiol on plasma gonadotrophins, maturation of the vaginal epithelium, metabolic parameters of bone resorption and menopausal symptoms (hot flushes, sleep disturbance, genitourinary discomfort and mood alteration) appear to be comparable to those of oral and subcutaneous estrogens, while the undesirable effects of oral estrogens on hepatic metabolism are avoided.
(17) Sleep alterations in addicted newborns could be related to central nervous system (CNS) distress caused by withdrawal.
(18) "Our black, Muslim and Jewish citizens will sleep much less easily now the BBC has legitimised the BNP by treating its racist poison as the views of just another mainstream political party when it is so uniquely evil and dangerous."
(19) Stage REM frequently appeared within 10 min of stage 1 onset and the normal sequence of stages REM and 4 were altered, demonstrating that the organization of sleep within a nap is quite different from that in monophasic nocturnal sleep.
(20) This result is discussed in terms of either a function of time-of-day effect or of prior sleep intensity.