(adv.) Wicked in the extreme; abominable; iniquitous; atrociously villainous; execrable; detestably vile.
Example Sentences:
(1) The author of the new bill, Mike Rogers, the Republican chair of the House intelligence committee , has said it is aimed at tracking the nefarious activities of hackers, terrorists and foreign states, especially China.
(2) But remember: record companies can be callous and nefarious beasts."
(3) "If there is evidence that a particular American is involved in terrorism or other nefarious activity, then intelligence and law enforcement agencies should absolutely investigate that person aggressively, by showing that evidence to a judge and getting a warrant.
(4) For decades she’s been portrayed as a Lady Macbeth involved in nefarious plots, branded as “a congenital liar” and accused of covering up her husband’s misconduct, from Arkansas to Monica Lewinsky.
(5) In the fevered Daily Mail version, this fact suggests a nefarious and hyperactive court, up to mischief and rejoicing in 'overruling' national authorities, better to promote the interests of sex offenders and the homicidal.
(6) The talks came as the RAF dropped "precision" weapons on the Central Organisation for Electronic Research, described by the Ministry of Defence as "a cover for the regime's nefarious activities".
(7) Muscular dysfunction has a nefarious effect on subsequent facial growth.
(8) Thor: The Dark World sees Chris Hemsworth's Asgardian prince forced to team up with Tom Hiddleston's crafty Loki to take down an even greater threat, Christopher Eccleston's nefarious Malekith.
(9) A few minutes’ walks away, are the Catacumbas del Beaterio , part of a network of tunnels used for nefarious and religious purposes: short tours began last year.
(10) The optional measure was designed to “provide DHS greater clarity and visibility to possible nefarious activity and connections by providing an additional tool set which analysts and investigators may use”.
(11) Pushkov claimed Moscow and the EU were looking to solve the gas dispute between Russia and Ukraine but were being stymied by Washington's nefarious plans.
(12) Meanwhile, Donald Trump appeared to accuse Obama of harbouring a nefarious secret agenda on national security, linking the president to the mass shooting.
(13) Look, he’s the clear frontrunner, he’s been in six debates already, answered more questions from the media than any other candidate on the stage combined.” The Fox News press release that irked Trump and led to his withdrawal read: “We learned from a secret back channel that the Ayatollah and Putin both intend to treat Donald Trump unfairly when they meet with him if he becomes president – a nefarious source tells us that Trump has his own secret plan to replace the Cabinet with his Twitter followers to see if he should even go to those meetings.” Trump derided it as “a wise guy press release .
(14) Until recently Bitcoin had been a largely obscure currency used by the tech-savvy , libertarians wishing to thumb their noses at central bankers and people involved in more nefarious activities such as online gambling (often illegal in the US) or drug deals .
(15) Time was one would head to that area whenever a nefarious local had gone missing because, in time, the body would wash up in the River Lee.
(16) It also warned that “the conviction and detention of an individual for being in a declared area where no evidence has been provided of a nefarious intent could be arbitrary for the purposes of international human rights law”.
(17) Naturally, such features can be used for nefarious ends too, but Taaki says that's the price to be paid for freedom.
(18) While I’m not interested in a specific individual, I’m interested in the emergent behaviour of the crowd.” Facebook Twitter Pinterest City-simulation company Simudyne creates computerised models ‘with pretty pictures’ to aid disaster-response planning But what about more nefarious bodies who are interested in specific individuals?
(19) Via nefarious means I've watched two episodes of Lilyhammer , BBC4's brand new "not very good thing with subtitles we're hoping to keep The Killing audience enraptured with", where a New York mob boss (Steven Van Zandt) goes into hiding in Norway with hilarious results.
(20) We all know about the military uses of drones (bomb lots of people, surveillance), and how drones can be used for nefarious purposes (theft, voyeurism), but there are actually some pretty cool uses for drones too.
Virulent
Definition:
(a.) Extremely poisonous or venomous; very active in doing injury.
(a.) Very bitter in enmity; actuated by a desire to injure; malignant; as, a virulent invective.
Example Sentences:
(1) The combined analysis of pathogenesis and genetics associated with the salmonella virulence plasmids may identify new systems of bacterial virulence and the genetic basis for this virulence.
(2) Escherichia enterotoxigenic strains, Yersinia enterocolitica and Salmonella typhimurium virulent strains, Campylobacter jejuni clinical isolates possess more pronounced capacity for adhesion to enteric cells of Peyer's plaques than to other types of epithelial cells, which may be of importance in the pathogenesis of these infections.
(3) The results are consistent with our previous suggestion that lethality for virulent SFV infection results from a lethal threshold of damage to neurons in the CNS and that attenuating mutations may reduce neuronal damage below this threshold level.
(4) The results point out the importance of detecting specific virulence factors before incriminating water as a source of human diarrhea.
(5) We put forward the hypothesis that the agglutinability in acriflavine, together with the PAGE profile type II, may be associated with particular structures responsible for virulence.
(6) One mutant, BS260, was completely noninvasive on HeLa cells and mapped to a region on the 220-kb virulence plasmid in which we had previously localized several avirulent temperature-regulated operon fusions (A.E.
(7) The proteins of two HEV isolates, one apathogenic (HEV-A) and one virulent (HEV-V), resembled each other in most respects.
(8) The geometric mean titers of anti-Shigella antibodies to virulence plasmid-associated antigens in milk received before infection were eightfold higher in infants who remained well than in those in whom diarrhea developed.
(9) Presented are the clinical, pathologic, and virulence features of sudden death due to Group A beta-hemolytic streptococcus.
(10) Some of these strains have been used by investigators to study gonococcal virulence.
(11) With the faster rate of proliferation there was a corresponding increase in virulence.
(12) On average, clinical isolates were not more virulent than fecal isolates.
(13) Since the four determining coefficients may change over evolutionary time-scales, the mathematical results together with a natural selection argument proves that virulence gamma 2 attenuates.
(14) It also devalues the courage of real whistleblowers who have used proper channels to hold our government accountable.” McCain added: “It is a sad, yet perhaps fitting commentary on President Obama’s failed national security policies that he would commute the sentence of an individual that endangered the lives of American troops, diplomats, and intelligence sources by leaking hundreds of thousands of sensitive government documents to WikiLeaks, a virulently anti-American organisation that was a tool of Russia’s recent interference in our elections.” WikiLeaks last year published emails hacked from the accounts of the Democratic National Committee and John Podesta, chairman of Hillary Clinton’s election campaign.
(15) Understanding the molecular biology of a virulence factor also provides information about potential targets for future therapies and preventive modalities.
(16) This ability may be associated with virulence, because an attenuated strain of L. pneumophila fails to multiply within this protozoan, whereas a virulent strain increases 10,000-fold in number when coincubated with T. pyriformis.
(17) Combinations of factors were generally more predictive for defining virulent clones, particularly in infants defined as being at normal risk of developing septicaemia.
(18) Strain IIBNV6, however, complemented with all virulent strains tested.
(19) Measurable activity on day 7 depended on infectious virus dose, virus virulence, and non-H-2 genetic background of the host.
(20) A related mechanism is proposed for the control of the virulence of animal viruses.