What's the difference between nicotine and tobacco?
Nicotine
Definition:
(n.) An alkaloid which is the active principle of tobacco. It is a colorless, transparent, oily liquid, having an acrid odor, and an acrid burning taste. It is intensely poisonous.
Example Sentences:
(1) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(2) The effect of the peptides on carbachol-induced 22Na+ flux into BC3H-1 cells, which contain nicotinic acetylcholine receptors on their surfaces, was measured.
(3) The compounds 1-3 in reaction with nicotine aldehyde or p-chlorobenzaldehyde were transformed into appropriate anilides of 2,3-epoxypropionic acid 4-9.
(4) The data suggest that the hypothalamic beta-E containing neurons were unable to adapt to nicotine's repeated effects on this system.
(5) The marine natural product lophotoxin has produced a non-reversible antagonism of parasympathetic and sympathetic functions that are known to be mediated by C6 sub-type nicotinic receptors.
(6) Stuart Forman and Keith Miller describe the physiological, biophysical and molecular biological evidence pointing to the location of a discrete allosteric site on the nicotinic acetylcholine receptor at which local anesthetics act.
(7) These impairments were seen in animals of both sexes, a finding which challenges the view that only females prenatally treated with nicotine show deficits in maze learning.
(8) Treatment with oxotremorine caused down-regulation of muscarinic receptors, while treatment with nicotine caused up-regulation of nicotinic receptors.
(9) Twelve young male smokers each participated in four conditions on 4 separate days: stress + nicotine, stress + placebo (stress alone), rest + nicotine (nicotine alone), and rest + placebo.
(10) More recently, it has been reported that individuals strongly reactive to psychological stress are also strongly reactive to nicotine.
(11) The beneficial effect of nicotine has been seen after both acute and chronic administration.
(12) At a concentration of 10 microM, tetraamine 4 did not affect histamine and 5-hydroxytryptamine receptors of guinea pig ileum or alpha-adrenoreceptors of guinea pig atria whereas it inhibited postsynaptic alpha-adrenoreceptors of rat vas deferens with a -log K value of 5.23 and nicotinic receptors of frog rectus abdominis with an IC50 value of 0.23 microM.
(13) With an 80% carbohydrate diet, the rate of catabolism from the plasma compartment rose by a mean of 39.1%; with nicotinic acid treatment, it fell by 42.2%.
(14) The inhibitory action of nicotine on plasma extravasation may contribute, in part, to the reported increased severity of arthritis in individuals who smoke.
(15) The inhibitory response was not decreased by treatment with atropine, hexamethonium, yohimbine or naloxone, suggesting that muscarinic, nicotinic, alpha 2 adrenergic or opiate receptors were not being stimulated.
(16) Dose-response curves to acetylcholine (ACh) and nicotine were established for pairs of tissues with and without epithelium, each pair receiving only one dose of nicotine.
(17) The effect of nicotine on the nervous system during rapid smoking of two calibrated cigarettes was measured in twenty subjects: light, medium, heavy and non-smokers, across the changes of a number of electrophysiological variables and in different situations.
(18) Tremors induced by chemical agents (nicotine, zinc and tremorine) were markedly inhibited by HA-966.
(19) Magnesium (Mg) deficiency, nicotine, and high dietary cholesterol are contributing factors that accentuate adverse effects of vitamin D.
(20) Orthodromic action potentials were initiated by excitatory postsynaptic potentials and mediated by nicotinic receptors.
Tobacco
Definition:
(n.) An American plant (Nicotiana Tabacum) of the Nightshade family, much used for smoking and chewing, and as snuff. As a medicine, it is narcotic, emetic, and cathartic. Tobacco has a strong, peculiar smell, and an acrid taste.
(n.) The leaves of the plant prepared for smoking, chewing, etc., by being dried, cured, and manufactured in various ways.
Example Sentences:
(1) The models are applied to estimate the demand for tobacco products in Finland.
(2) There was however no difference in the cross-sectional studies and no significant deleterious effect detected of tobacco use on forearm bone mineral content.
(3) They have actively intervened with governments, and particularly so in Africa.” José Luis Castro, president and chief executive officer of Vital Strategies, an organisation that promotes public health in developing countries, said: “The danger of tobacco is not an old story; it is the present.
(4) How big tobacco lost its final fight for hearts, lungs and minds Read more Shares in Imperial closed down 1% and British American Tobacco lost 0.75%, both underperforming the FTSE100’s 0.3% decline.
(5) The history of tobacco production and marketing is sketched, and the literature on chronic diseases related to smoking is summarized for the Pacific region.
(6) The mechanism by which such high levels were attained was primrily a combination of arterial hypoxia and a high carbon monoxide yield from tobacco.
(7) This structure could be constructed in intron 1 of tobacco rps12 gene.
(8) An important stratification factor, however, was related to tobacco usage.
(9) Chadwick felt that Customs and Trading Standards needed to continue their war on illegal tobacco – if not, efforts to tackle smoking could be undermined.
(10) These regions are also conserved in chloroplast DNA of tobacco.
(11) The policy was effective in reducing perceived environmental tobacco smoke exposure in work areas where smoking was banned but not in nonwork areas where smoking was allowed in designated areas.
(12) The group of tobacco smoking persons showed during rest, loads and in the restorative period more distinct disorders of cardio-vascular system values.
(13) Future increasing segments of females addicted to tobacco smoking will obviously markedly influence sex difference in morbidity.
(14) The Macassans traded iron, tobacco, cloth and gin for access to Yolngu waters.
(15) The present article reports a study of how such lifestyle habits, notably alcohol and tobacco consumption, are addressed in medical consultations.
(16) Cigarette smokers did not differ significantly from users of smokeless tobacco regarding hypercholesterolemia.
(17) However, most of these studies are difficult to interpret because they do not correctly take into account associated carcinogens such as tobacco smoke and other occupational carcinogens.
(18) The acute effects of smokeless tobacco (ST) on buccal mucosal transport and barrier function were studied by means of in vivo and in vitro techniques.
(19) The predilection of localization of epidermoid and small cell carcinomas in the upper lobes suggests a possible relationship to tobacco smoke inhalation as these regions have been shown to be more affected by the smoke.
(20) We have isolated an auxin-regulated cDNA, parB, from the early stage of cultured tobacco mesophyll protoplasts.