(n.) A jag, or snag; a knob; a protuberance; also, the point or gist, as of a story.
Example Sentences:
(1) Out of the latter, NUB congenital defect was in 4, total epispadia in 1, spina bifida in 1 patient.
(2) In the case of S. enteritidis NUB 31, the effect of CPS-K was detectable only when more than 20 mug per mouse was injected.
(3) And that is the nub of the FT report: grim reading for chancellor George Osborne as he puts the finishing touches to his 19 March budget.
(4) The peak CPS-K effect on infection with S. enteritidis NUB 1 was seen when given immediately before bacterial challenge.
(5) Some wore "slave bracelets" made out of boot laces and walked with "Black Power canes", sticks with the nub carved into a clenched fist.
(6) This is the nub of the issue and the foreign secretary's statement seems to mask a much more complex picture.
(7) Four new nuB mutations in the DNA gyrase-binding site between the G and I genes were also sequenced and found to be identical to the nuB103 mutation sequenced previously.
(8) The nub of Zittrain’s concern is that the practice of shaping what stays and what goes from the database is hopelessly individualistic.
(9) The promotion of infection with S. enteritidis NUB 1 by CPS-K depended upon its dose, the effect of CPS-K being demonstrable up to as little as 0.2 mug per mouse.
(10) This is the nub of what I am going to call, because I've always secretly wanted to be a mathematician, the "Birmingham Liberty Paradox".
(11) And I'm hopeful that we're getting closer to the nub of the problem.
(12) The nub of the controversy was his comment that "we wouldn't have had all these problems over all these years" if Mr Thurmond, who ran a campaign to keep blacks out of white schools and neighbourhoods, had won the presidency in 1948.
(13) Both have seen very bleak scenarios depicted by either side in attempts to scare the electorate, for example with the idea that a yes vote will usher in a very authoritarian regime.” In his presentations, Baldini, who will vote yes, tries to go to what he sees as the nub of the issue.
(14) Our failing economy needs stimulating and your nub of grey meat and Mars egg are simply not sufficient.
(15) Why does it matter whether other people believe it or not?” I suspect that gets to the nub of it.
(16) As a result of enumeration of bacterial populations in the peritoneal washing, blood, liver and spleen, it was revealed that CPS-K promoted in vivo growth of S. enteritidis NUB 1 and NUB 31.
(17) The NUB-6 cell line consisted of two distinct cell subtypes, small typical neuroblasts and larger spheroid-forming cells, while NUB-7 was homogeneously neuroblastic.
(18) All the children were operated on: NUB reconstruction according to Davis, bilateral uretero-cystostomy according to Coen.
(19) Two new neuroblastoma (NB) cell lines, NUB-6 and NUB-7, were established from recurrent and primary NB tumours respectively and identified conclusively as NB by their phenotypic characteristics, catecholamine production and N-myc amplification.
(20) Urodynamic studies showed the absence of detrusor-sphincter dyssynergia and confirmed organic nature of NUB lesion.
Pith
Definition:
(n.) The soft spongy substance in the center of the stems of many plants and trees, especially those of the dicotyledonous or exogenous classes. It consists of cellular tissue.
(n.) The spongy interior substance of a feather.
(n.) The spinal cord; the marrow.
(n.) Hence: The which contains the strength of life; the vital or essential part; concentrated force; vigor; strength; importance; as, the speech lacked pith.
(v. t.) To destroy the central nervous system of (an animal, as a frog), as by passing a stout wire or needle up and down the vertebral canal.
Example Sentences:
(1) Finally, fosinopril had no effect on the pressor or chronotropic effects of norepinephrine (NE) or 1,1-dimethyl-4-phenylpiperinium (DMPP) or electrical stimulation of the sympathetic ganglia of pithed rats.
(2) Relatively weaker GUS activity was also detected in pith parenchyma.
(3) Both d- and l-amphetamine were also compared for their pressor and tachycardic activity in pithed rats.
(4) Intravenous administration of T-2 to pithed rats did not alter blood pressure or heart rate at a time when, in conscious rats, both blood pressure and heart rate were increased.
(5) Monoiodo-Ang II was found to be a potent, full agonist in in vivo bioassays and a more potent (2.5-fold) pressor agent than the native hormone Ang II in the pithed rat.
(6) APP 201-533 [3-amino-6-methyl-5-phenyl-2(1H)-pyridinone] was investigated in vivo in anesthetized and unanesthetized dogs and pithed open-chest cats and in vitro in guinea pig atria and papillary muscles, skinned muscle fibers from pig hearts, and rat myocardium.
(7) The effects of quinpirole, a specific dopamine DA2 receptor agonist, on autonomic nervous control of heart rate, were studied in normotensive pithed rats, by analysing its action on the tachycardia and bradycardia evoked by electrical stimulation of the cardioaccelerator (10 V; 1 ms; 0.5, 1, 3, 6 Hz) and vagus (10 V; 1 ms; 3, 6, 9 Hz) nerves respectively.
(8) Pith cells can shift from the C- to the C+ state by a process known as habituation.
(9) The pressor actions of ET3 and arginine vasopressin (AVP) were compared with one another in pithed rats in the presence of the calcium channel activator BAY K 8644 or the calcium channel antagonist nifedipine i.a.
(10) Both human endothelin 1 (ET1) and rat endothelin 3 (ET3) produced dose-dependent pressor effects in the pithed rat.
(11) Viprostol did not antagonize the tachycardia induced by stimulation of the discrete segments at C7-T1 (cardio-accelerator) of the spinal cord in pithed SHR, suggesting that viprostol did not activate the presynaptic alpha-adrenoceptors.
(12) In pithed rats, the vasopressor response to dihydroergotoxine was reduced competitively by yohimbine, and non-competitively by nifedipine, but not by prazosin or methysergide, showing that the vasoconstriction is mediated by alpha 2-adrenoceptors.
(13) The antagonistic effects of a new inositol phosphate derivative, D-myoinositol-1,2,6-trisphosphate (PP56), on pressor responses to preganglionic sympathetic nerve stimulation and exogenously administered phenylephrine or neuropeptide Y (NPY) were investigated in vivo in the pithed rat.
(14) We conclude that in contrast to the increase in diastolic pressure elicited by B-HT 920, calcium channels are not involved in the cirazoline-induced pressor responses in the pithed cat.
(15) Acute or chronic adrenalectomy did not alter the pressor responses and chronotropic effect of angiotensin in the pithed rat.
(16) Habituated cells derived from inducible pith cells give rise to normal plants whose leaf and pith tissues require cytokinin for growth in culture.
(17) The endovenous perfusion of the splenic material in acidified and alkalinized forms caused significant increases of the mean blood pressure in normal, vagotomized and pithed rats, showing that, in contradiction to previous reports, changes in pH did not affect its hypertensive activity.
(18) The dose-response curves of three alpha-agonists noradrenaline, St 587 and B-HT 933 in pithed rats were shifted rightwards by pretreatment (i.v.
(19) In pithed rats, only pindolol produced a definite fall of blood pressure.
(20) The bradycardia was reduced but not blocked by pre-treatment with guanethidine, yohimbine, propranolol or pithing.