(n.) Originally, an elf's child; a changeling left by fairies or goblins; hence, a deformed or foolish child; a simpleton; an idiot.
Example Sentences:
(1) Big OAF was converted to little OAF by equilibration in 1 M NaCl or 2 M urea.
(2) Outside, there’s no sign of life except one bearded oaf on a chopper and a kid at the back door, holding a picture of Hot Fuss-era Brandon Flowers , praying for a brief encounter.
(3) The effect of interleukin-1 beta, the major component of osteoclast-activating factor (OAF), on bone formation by fetal rat osteoblast-rich cells was investigated.
(4) Recent studies show that osteoclast activating factor (OAF) is homologous to IL-1B.
(5) The resorption response to OAF also resembles that of PTH in having a steep dose response curve and being only transiently inhibited by calcitonin and partially inhibited by increasing medium phosphate concentration.
(6) Spleen cells treated with mitogens produce a potent bone-resorbing factor called osteoclast-activating factor (OAF).
(7) In contrast, supernatant fluids from concanavalin A (Con-A)-activated murine spleen cell cultures (murine osteoclast-activating factor; OAF) consistently and significantly induced a 3- to 5-fold stimulation of bone resorption in this system.
(8) OAF production is probably related to the nature of hydrocarbons in the air.
(9) Calcium release was significantly increased for all agents between 12 and 24 h. It is concluded that bone resorption by 1,25(OH)2D3, OAF, and PGE2 is mediated primarily by increased activity of existing osteoclasts similar to PTH activation.
(10) The presence of bactericidal compounds (open air factor = OAF) could be demonstrated on several days and quantitated in relative units of OAF concentration.
(11) The current studies were designed to produce monoclonal antibodies against OAF for use in the subsequent design of immunoassays for OAF in clinical samples.
(12) In this study we examined the relationship between the lymphocyte and monocyte in OAF production.
(13) The lymphokine osteoclast-activating factor (OAF) was purified to homogeneity.
(14) These results indicate that prostaglandin synthesis is necessary for OAF production.
(15) Are there really "nine sleeps 'til new Who" you gurgling oaf?
(16) Bones from mi mice showed a generalized resorption defect with decreased spontaneous or control resorption and failure to respond to parathyroid hormone (PTH), prostaglandin E2, 1,25 dihydroxy vitamin D3, vitamin A, or osteoclast activating factor (OAF) from human peripheral leukocytes or mouse spleen cells.
(17) OAF release was stimulated by pokeweed mitogen and concanavalin A as well as by phytohemagglutinin.
(18) When PGE1 and PGE2 (0.1 microM) were added exogenously to the enriched lymphocyte population, OAF release occurred after stimulation with PHA.
(19) We have further characterized osteoclast activating factor (OAF) using a bioassay for bone resorption which utilizes the release of previously incorporated (45)Ca from fetal rat long bones in organ culture.
(20) The demonstration of increased osteoclast activating factor (OAF) derived from the cultured myeloma cells from each case suggests that the secretion of OAF and immunoglobulin are unrelated.
Oafish
Definition:
(a.) Like an oaf; simple.
Example Sentences:
(1) One Round (Danny Green) is the oafish representative of the British masses.
(2) The winger made Jonny Evans seem oafish as he feinted his way past him on the right and then glided 20 yards forward before racing into the box, past Jonas Olsson, and firing into the net despite an attempted block by Craig Dawson.
(3) The cast of The Five vacillated between feigned solemnity and jocular NFL pregame oafishness.
(4) The striker's first touch was oafish, allowing Sorensen to surge out to smother.
(5) Being a chortling oaf not only makes you critically bulletproof – oafish chortling being a perpetual escape pod – it functions as a kind of cloaking device, somehow obscuring the notion that you're a politician at all.
(6) Dante, who's already booked, oafishly knees Reus in the chest!
(7) It would be a mistake to dismiss Trump as some oafish “man baby” who impulsively blurts out whatever comes into his mind.
(8) Carroll may be uncouth as a footballer but he has an ability to make almost any defender look oafish – Roy Hodgson might just consider that a precious trait when he selects his World Cup squad.
(9) I couldn’t accept what was going on in the first half.” The players’ response spoke volumes for the malaise at the club – within three minutes of the resumption they were 3-0 down, Ulloa slamming a penalty into the net after Rivière was punished for an oafish challenge on the Leicester defender Marcin Wasilewski.
(10) In an oafish article published last week in the Financial Times, Martin Taylor, the chairman of WH Smith, declared that Germany, in cahoots with France, remains one of our principal rivals.