(n.) Originally, an elf's child; a changeling left by fairies or goblins; hence, a deformed or foolish child; a simpleton; an idiot.
Example Sentences:
(1) Big OAF was converted to little OAF by equilibration in 1 M NaCl or 2 M urea.
(2) Outside, there’s no sign of life except one bearded oaf on a chopper and a kid at the back door, holding a picture of Hot Fuss-era Brandon Flowers , praying for a brief encounter.
(3) The effect of interleukin-1 beta, the major component of osteoclast-activating factor (OAF), on bone formation by fetal rat osteoblast-rich cells was investigated.
(4) Recent studies show that osteoclast activating factor (OAF) is homologous to IL-1B.
(5) The resorption response to OAF also resembles that of PTH in having a steep dose response curve and being only transiently inhibited by calcitonin and partially inhibited by increasing medium phosphate concentration.
(6) Spleen cells treated with mitogens produce a potent bone-resorbing factor called osteoclast-activating factor (OAF).
(7) In contrast, supernatant fluids from concanavalin A (Con-A)-activated murine spleen cell cultures (murine osteoclast-activating factor; OAF) consistently and significantly induced a 3- to 5-fold stimulation of bone resorption in this system.
(8) OAF production is probably related to the nature of hydrocarbons in the air.
(9) Calcium release was significantly increased for all agents between 12 and 24 h. It is concluded that bone resorption by 1,25(OH)2D3, OAF, and PGE2 is mediated primarily by increased activity of existing osteoclasts similar to PTH activation.
(10) The presence of bactericidal compounds (open air factor = OAF) could be demonstrated on several days and quantitated in relative units of OAF concentration.
(11) The current studies were designed to produce monoclonal antibodies against OAF for use in the subsequent design of immunoassays for OAF in clinical samples.
(12) In this study we examined the relationship between the lymphocyte and monocyte in OAF production.
(13) The lymphokine osteoclast-activating factor (OAF) was purified to homogeneity.
(14) These results indicate that prostaglandin synthesis is necessary for OAF production.
(15) Are there really "nine sleeps 'til new Who" you gurgling oaf?
(16) Bones from mi mice showed a generalized resorption defect with decreased spontaneous or control resorption and failure to respond to parathyroid hormone (PTH), prostaglandin E2, 1,25 dihydroxy vitamin D3, vitamin A, or osteoclast activating factor (OAF) from human peripheral leukocytes or mouse spleen cells.
(17) OAF release was stimulated by pokeweed mitogen and concanavalin A as well as by phytohemagglutinin.
(18) When PGE1 and PGE2 (0.1 microM) were added exogenously to the enriched lymphocyte population, OAF release occurred after stimulation with PHA.
(19) We have further characterized osteoclast activating factor (OAF) using a bioassay for bone resorption which utilizes the release of previously incorporated (45)Ca from fetal rat long bones in organ culture.
(20) The demonstration of increased osteoclast activating factor (OAF) derived from the cultured myeloma cells from each case suggests that the secretion of OAF and immunoglobulin are unrelated.
Off
Definition:
(adv.) In a general sense, denoting from or away from; as:
(adv.) Denoting distance or separation; as, the house is a mile off.
(adv.) Denoting the action of removing or separating; separation; as, to take off the hat or cloak; to cut off, to pare off, to clip off, to peel off, to tear off, to march off, to fly off, and the like.
(adv.) Denoting a leaving, abandonment, departure, abatement, interruption, or remission; as, the fever goes off; the pain goes off; the game is off; all bets are off.
(adv.) Denoting a different direction; not on or towards: away; as, to look off.
(adv.) Denoting opposition or negation.
(interj.) Away; begone; -- a command to depart.
(prep.) Not on; away from; as, to be off one's legs or off the bed; two miles off the shore.
(a.) On the farther side; most distant; on the side of an animal or a team farthest from the driver when he is on foot; in the United States, the right side; as, the off horse or ox in a team, in distinction from the nigh or near horse or ox; the off leg.
(a.) Designating a time when one is not strictly attentive to business or affairs, or is absent from his post, and, hence, a time when affairs are not urgent; as, he took an off day for fishing: an off year in politics.
(n.) The side of the field that is on the right of the wicket keeper.