(n.sing. & pl.) That which is produced; a child or children; a descendant or descendants, however remote from the stock.
(n.sing. & pl.) The act of production; generation.
(n.sing. & pl.) Origin; lineage; family.
Example Sentences:
(1) No reversions to wild-type levels were observed in 555 heterozygous offspring of crosses between homozygous Campines and normals.
(2) In neither case has a significant elevation in inherited genetic effects or cancer been detected in the offspring of exposed individuals.
(3) For that reason we determine basal serum pepsinogen I (PG I) levels in 25 ulcerous patients and 75% of their offspring and to a control group matched by age and sex.
(4) The analgesic activity of morphine was assessed by the hot-plate technique in the offspring of female CFE rats that had received morphine twice daily on days 5 to 12 of pregnancy.
(5) The mothers of 87 male and female adolescents accepted at a counseling agency described their offspring by completing the Institute of Juvenile Research Behavior Checklist.
(6) Neither light nor electron microscopy revealed significant morphologic alterations in the cochlear elements of the exposed offspring.
(7) The relationships of birth weight and maternal diabetes to the development of obesity were examined at 5-19 yr of age in the offspring of Pima Indian women.
(8) The data of first 1000 first-born, non-malformed, mature (greater than or equal to 2500 g) offspring of participants in the Hungarian "Optimal" Family Planning Programme were evaluated.
(9) Subcutaneous polymorphic sarcomas were induced in 8 out 27 offspring of syrian golden Hamsters after treatment of pregnant mother animals at day 15 of gestation with Adenovirus 12.
(10) Here we show that the subsequent survival and reproductive success of subordinate female red deer is depressed more by rearing sons than by rearing daughters, whereas the subsequent fitness of dominant females is unaffected by the sex of their present offspring.
(11) The residual values were positively correlated in parent-offspring pairs and among sibs, both those presumed to be living together and those presumed to be living apart.
(12) The five offspring are ancestors of all known carriers.
(13) We have studied the effect of ampicillin and cloxacillin treatment of mice in the final week of pregnancy on the development of the lymphatic system of their offsprings.
(14) It was caused at the frequency close to 100% in dysgenic offsprings reared above 25 degrees C, of which gonads were morphologically clearly different from those of usual GD sterility, whereas there was no indication of GD-3 sterility at temperatures below 24 degrees C. Temperature sensitive period of GD-3 sterility was estimated to the prepupal stage by shift-down experiment.
(15) The effects of repeated N2O exposures were investigated for offspring of mice exposed to air or N2O (5%, 15%, or 35%) for 4 hours per day on days 6 through 15 of pregnancy.
(16) Whether normal individuals with such a duplication carry increased risk of having offspring with an obesity syndrome is yet to be determined.
(17) Offspring of marmosets reached adult values of 14CO2 exhalation at 8 days postnatally when using [14CO2]-methacetin as substrate and at 30 days postnatally using [14C2H5]-phenacetin in the breath test.
(18) The sample consisted of 102 Japanese families, each including both parents and one of their offspring, and on average all subjects had relatively well-aligned permanent dentitions.
(19) At Day 56, serum IgM concentrations were significantly lower in the low zinc offspring.
(20) Such conditions may influence the personality of offspring of deaf-mute people.
Progenitor
Definition:
(n.) An ancestor in the direct line; a forefather.
Example Sentences:
(1) The effects of in vivo administration of native prostaglandin E2 (PGE) on the cycling status of the granulocyte-monocyte progenitor cell (CFU-GM) were examined in a mouse model.
(2) In healthy persons the supernatant of lymphocytes preincubated with PHA and ALG was found to show a stimulating effect to clonogenic properties of marrow progenitors, the mentioned effect being not in proportion to the concentration value.
(3) We therefore think that the detailed examination of CALLA(-) non-T non-B ALL cells using myeloid specific antibodies is helpful in clarifying the characteristics of myeloid precursors and the common bipotential stem cell of lymphoid and myeloid progenitors.
(4) The high levels of circulating progenitor cells in ALL and CLL patients clearly distinguish them from other cytopenic hematological malignancies, in which decreased progenitor cell levels have been demonstrated previously (acute myeloid leukemia, hairy cell leukemia).
(5) Studies on proliferation and differentiation of granulocyte-monocyte progenitor cells in Chediak-Higashi syndrome (CHS) were done on a 1-month-old patient, using the soft-agar bone marrow culture technique.
(6) Certain mouse and human hematopoietic progenitor cells also contain an aldehyde dehydrogenase that catalyzes the detoxification of aldophosphamide, but the specific identity of this enzyme remains to be established.
(7) Mouse spleen cells rich in erythroid progenitors were washed free of endogenous Epo and then incubated in the absence of Epo.
(8) The bone marrow differentials and numbers of granulocyte-macrophage progenitors (CFC-GM) were determined after irradiation with 1.5 Gy.
(9) However, the studies on 0-2A progenitor cells were carried out in bulk cultures of optic nerve, and so it was possible that other cell-cell interactions were required for differentiation in culture.
(10) In culture, GY30 cells sustain the production of granulocyte-macrophage progenitor cells (GM-CFU) but fail to support the survival of pluripotential stem cells (CFU-S).
(11) The development of T cells from stem (progenitor) cells to effector cells results from a two-wave process of proliferation and differentiation.
(12) No chemical or immunological differences were observed in the cell wall carbohydrate of the noncapsulated streptococcus, 89R50, and that of its capsulated progenitor.
(13) This is exemplified in lymphoma cells (chronic lymphocytic leukemia of B or T type, Sezary Syndrome, immunocytoma) that resemble mature and immunocompetent T and B cells, in T cell acute lymphoblastic leukemia (T-ALL) (equivalent to thymus cells) and in non-T ALL (corresponding to lymphoid progenitor cells in the bone marrow).
(14) We studied MDS-associated inhibitory activity, which inhibited colony formation in vitro of granulocyte-macrophage progenitors (CFU-GM).
(15) In contrast, populations containing BFUe yielded a striking (sixfold for CFUe; 23-fold for e-clusters) expansion of late progenitors in the presence of Epo.
(16) The stem cell loss immediately following 55Fe injection is in our interpretation caused by rapid differentiation along the erythroid pathway in a response that involves all progenitor populations.
(17) We report here that human IL-6 and IL-3 act synergistically in support of the proliferation of progenitors for human blast cell colonies and that IL-1 alpha reveals no synergism with IL-3 when tested against purified human marrow progenitors.
(18) In addition, we have examined the ability of these fibroblasts and their conditioned medium (CM) to induce differentiation of human hemopoietic progenitor cells.
(19) AF and its deacetylated form inhibited the development of macrophage and granulocytic colonies from progenitor cells in human bone marrow even at concentrations less than or equal to 10(-9)M. The disease suppressive activity of AF could result in part from the reduction of cell numbers in arthritic lesions and our findings provide a mechanism for this possibility.
(20) Spontaneously hypertensive rats (SH) with an increased number of red blood cells (RBC), microcytosis, and normal hemoglobin (Hb) concentration were used to study the effect of different manipulations of the erythron on erythropoietin production and on erythroid progenitor proliferation by bone marrow cells in order to gain insight regarding the regulation of erythropoiesis.