(n.) Originally, a medicine of a thicker consistence than sirup, prepared with opium.
(n.) Any medicine that contains opium, and has the quality of inducing sleep or repose; a narcotic.
(n.) Anything which induces rest or inaction; that which quiets uneasiness.
(a.) Inducing sleep; somniferous; narcotic; hence, anodyne; causing rest, dullness, or inaction; as, the opiate rod of Hermes.
(v. t.) To subject to the influence of an opiate; to put to sleep.
Example Sentences:
(1) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(2) Opiate agonists and endogenous opioid peptides inhibit electrolyte secretion both in vitro and in vivo.
(3) It appears that tricyclic antidepressants act in a fashion different from opiate drugs that alter the sensory discriminative component of pain.
(4) The results are discussed with reference to the possible mechanism(s) via which injected and endogenous opiates may affect motor performance by attenuating GABA transmission in the nigra.
(5) Pharmacological data suggest that opiates, acting indirectly via the catecholaminergic system, are involved in the inhibition of LH release and the stimulation of PRL secretion.
(6) Such disturbances may be induced by opiates, benzodiazepines, phenothiazines, butyrophenones, ketamine, etomidate, propofol, nitrous oxide, and halogenated inhalation anesthetics as well as by H2-blocking agents such as cimetidine.
(7) From these results, we conclude that opiate peptides are released in response to the suckling stimulus in the cynomolgus monkey and that they mediate the effects of suckling on PRL secretion in both gonadal-intact and agonadal cynomolgus monkeys.
(8) Its potency is 4-5 times greater than that of the opiate antagonist naloxone.
(9) A cost-effective immunoassay for the detection of opiates in urine has been developed using commercial reagents on a centrifugal analyser.
(10) Drugs used to promote food intake and weight gain, such as cyproheptadine, amitriptyline, clonidine and opiate antagonists, have provided disappointing results.
(11) An alternative approach, which correlates the structure-activity data of opiate compounds with that of the enkephalins, is described and shown to produce a model consistent with the available structure-activity data.
(12) However, opiate treatment is not a new therapeutic concept in psychiatry.
(13) The inhibitory response was not decreased by treatment with atropine, hexamethonium, yohimbine or naloxone, suggesting that muscarinic, nicotinic, alpha 2 adrenergic or opiate receptors were not being stimulated.
(14) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(15) We report that exposure of rat spinal cord-dorsal root ganglion cocultured neurons to kappa-opiate agonist is accompanied by a 60-70% reduction in the level of the alpha i subunit of GTP-binding proteins.
(16) Cerebrospinal fluid (CSF) opiate activity has been found to be elevated in two studies.
(17) PBEir increased with both opiates immediately after initiation of CPB and remained so during the rest of the study.
(18) Diclofenac is an alternative to opiates in the management of postoperative pain.
(19) On the other hand, if the tissue-derived opiates were from prodynorphin, only Leu-enkephalin should be found.
(20) Analysis of patient questionnaires suggests more enthusiasm for patient-controlled analgesia, but in this study, it was difficult to clearly demonstrate any significant advantage for pain management or amount of opiate administered.
Opinion
Definition:
(n.) That which is opined; a notion or conviction founded on probable evidence; belief stronger than impression, less strong than positive knowledge; settled judgment in regard to any point of knowledge or action.
(n.) The judgment or sentiment which the mind forms of persons or things; estimation.
(n.) Favorable estimation; hence, consideration; reputation; fame; public sentiment or esteem.
(n.) Obstinacy in holding to one's belief or impression; opiniativeness; conceitedness.
(n.) The formal decision, or expression of views, of a judge, an umpire, a counselor, or other party officially called upon to consider and decide upon a matter or point submitted.
(v. t.) To opine.
Example Sentences:
(1) Without medication atypical ventricular tachycardia develops, in the author's opinion, most probably when bradycardia has persisted for a prolonged period.
(2) For some time now, public opinion polls have revealed Americans' strong preference to live in comparatively small cities, towns, and rural areas rather than in large cities.
(3) One thing seems to be noteworthy in their opinion: the bacterial resistance of the germs isolated from the urine is bigger than the one of the germs isolated from the respiratory apparatus.
(4) In self-opinions on own appearance the children mentioned teeth as a feature which they would like to change as first.
(5) True, Syria subsequently disarmed itself of chemical weapons, but this was after the climbdown on bombing had shown western public opinion had no appetite for another war of choice.
(6) In our opinion, a carcinologically "malignant" metastatic myxoma remains a questionable pathological entity.
(7) It can feel as though an official opinion has been issued.
(8) Although individual IRB chairpersons and oncology investigators may have important differences of opinion concerning the ethics of phase I trials, these disagreements do not represent a widespread area of ethical conflict in clinical research.
(9) However, controversy and differing opinions about the disbursement of contraceptives remains.
(10) In his notorious 1835 Minute on Education , Lord Macaulay articulated the classic reason for teaching English, but only to a small minority of Indians: “We must do our best to form a class who may be interpreters between us and the millions whom we govern; a class of persons, Indians in blood and colour, but English in taste, in opinions, in morals and in intellect.” The language was taught to a few to serve as intermediaries between the rulers and the ruled.
(11) The authors are of the opinion that the processes occurring in the neighbourhood of the traumatic skin wound can be influenced and that regeneration can be regulated.
(12) In this way, we tried to find out how the patients experience the treatment and stay on the Unit, what is most helpful in solving their problems and what are, in their opinion, the direct gains of hospitalization.
(13) Twellman has steadily grown in confidence as he settles into his role, though whether as a player or as an advocate he was never shy about voicing his opinions.
(14) He told FA.com: “In my opinion, we were worthy winners.
(15) But under Comey’s FBI, the agency has continued to disregard the justice department’s legal opinion, and to this day, demands tech companies hand it all sorts of data under due-process free National Security Letters.
(16) The current opinion, based on different clinical tests, is that parasympathetic impairment occurs earlier in autonomic dysfunctions.
(17) In our opinion, this is the first case of that condition reported in this country.
(18) Piccoli followed that up with an opinion piece for Fairfax Media on Thursday in which said the SES model never applied to public schools and was not properly targeted to student needs.
(19) After presenting some incontestable facts of CSF-physiology the actual and quite controversial opinions on ventricular and extraventricular sources of CSF as well as the mechanism of CSF-absorption are discussed.
(20) Mark Rasch, a cyber crime expert quoted by the FT, meanwhile said recent events have been “a serious and devastating attack to [Sony’s] reputation and image”, and his opinion is played out by a new YouGov poll into the public perception of Sony’s brand.