(n.) Originally, a medicine of a thicker consistence than sirup, prepared with opium.
(n.) Any medicine that contains opium, and has the quality of inducing sleep or repose; a narcotic.
(n.) Anything which induces rest or inaction; that which quiets uneasiness.
(a.) Inducing sleep; somniferous; narcotic; hence, anodyne; causing rest, dullness, or inaction; as, the opiate rod of Hermes.
(v. t.) To subject to the influence of an opiate; to put to sleep.
Example Sentences:
(1) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(2) Opiate agonists and endogenous opioid peptides inhibit electrolyte secretion both in vitro and in vivo.
(3) It appears that tricyclic antidepressants act in a fashion different from opiate drugs that alter the sensory discriminative component of pain.
(4) The results are discussed with reference to the possible mechanism(s) via which injected and endogenous opiates may affect motor performance by attenuating GABA transmission in the nigra.
(5) Pharmacological data suggest that opiates, acting indirectly via the catecholaminergic system, are involved in the inhibition of LH release and the stimulation of PRL secretion.
(6) Such disturbances may be induced by opiates, benzodiazepines, phenothiazines, butyrophenones, ketamine, etomidate, propofol, nitrous oxide, and halogenated inhalation anesthetics as well as by H2-blocking agents such as cimetidine.
(7) From these results, we conclude that opiate peptides are released in response to the suckling stimulus in the cynomolgus monkey and that they mediate the effects of suckling on PRL secretion in both gonadal-intact and agonadal cynomolgus monkeys.
(8) Its potency is 4-5 times greater than that of the opiate antagonist naloxone.
(9) A cost-effective immunoassay for the detection of opiates in urine has been developed using commercial reagents on a centrifugal analyser.
(10) Drugs used to promote food intake and weight gain, such as cyproheptadine, amitriptyline, clonidine and opiate antagonists, have provided disappointing results.
(11) An alternative approach, which correlates the structure-activity data of opiate compounds with that of the enkephalins, is described and shown to produce a model consistent with the available structure-activity data.
(12) However, opiate treatment is not a new therapeutic concept in psychiatry.
(13) The inhibitory response was not decreased by treatment with atropine, hexamethonium, yohimbine or naloxone, suggesting that muscarinic, nicotinic, alpha 2 adrenergic or opiate receptors were not being stimulated.
(14) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(15) We report that exposure of rat spinal cord-dorsal root ganglion cocultured neurons to kappa-opiate agonist is accompanied by a 60-70% reduction in the level of the alpha i subunit of GTP-binding proteins.
(16) Cerebrospinal fluid (CSF) opiate activity has been found to be elevated in two studies.
(17) PBEir increased with both opiates immediately after initiation of CPB and remained so during the rest of the study.
(18) Diclofenac is an alternative to opiates in the management of postoperative pain.
(19) On the other hand, if the tissue-derived opiates were from prodynorphin, only Leu-enkephalin should be found.
(20) Analysis of patient questionnaires suggests more enthusiasm for patient-controlled analgesia, but in this study, it was difficult to clearly demonstrate any significant advantage for pain management or amount of opiate administered.
Unrealistic
Definition:
Example Sentences:
(1) Some of its demands are wildly unrealistic, such as the reintroduction of direct rule and the suspension of devolution.
(2) However, this volume of blood is an unrealistic amount to take from the frequently febrile pediatric patient.
(3) Following the Iranian Ministry of Culture and Islamic Guidance's Hoax of Hollywood conference in Tehran this week, it has been reported that Iran may "sue Hollywood" over what it considers to be unrealistic portrayals of the country in several films.
(4) Or is this new low just as unrealistic as the original high?
(5) The simplest models make a variety of unrealistic assumptions and an outline is presented of how the assumptions of fingerprint band population frequency equality and mutation rate constancy can be relaxed to produce a more realistic and powerful model.
(6) Labour said it would not respond to the threat posed by Ukip by supporting unrealistic targets for net migration or proposing radical changes to the free movement of workers which would probably be rejected by the rest of the EU.
(7) Tony Pulis hopes his only transfer business before the close of play at 11pm on Monday is incoming rather than outgoing at West Bromwich Albion but the manager has warned against unrealistic expectations if Saido Berahino remains after the striker marked his return with two goals.
(8) Furthermore, a careful selection of the facts to be documented must be established, because a "complete clinical documentation" is unrealistic.
(9) It’s not complicated and it’s not an unrealistic wish list.
(10) Unfortunately most of these neural nets are unrealistic in important respects.
(11) But he concluded: "You've been evasive, repetitive and unrealistic."
(12) It is a totally unrealistic, pessimistic vision about what this country can achieve."
(13) Our main finding is that most addicts have a strong interest in training and employment services, but their expectations about the impact of such services is often unrealistic.
(14) But the scale needed, the expense and the potential unintended consequences are so great that it is widely considered unrealistic.
(15) Because this is often unrealistic, the only other way to keep these patients free of disease is by total dental extraction.
(16) This implies also the tendency that the average food intake estimated through FFQs can yield unrealistically high values for items consumed frequently.
(17) Unrealistic aim The executive does not dispute that the magazine division holds appeal for mass-market publishers such as IPC, Bauer and National Magazines, however, all of which could save significant sums through back office synergies.
(18) The German chancellor, Angela Merkel, demanded a European monitoring mission in Ukraine, but conceded it would be “quite unrealistic” for the Russians to allow such a mission into Crimea .
(19) Urinary incontinence is a common occurrence in long term care and, given the client population, continence is often an unrealistic expectation.
(20) The latter calculation was lower than the ESD in three of the five instances examined, which seems unrealistic.