(v. t.) To get the better of; to surmount; to conquer; to subdue; as, to overcome enemies in battle.
(v. t.) To overflow; to surcharge.
(v. t.) To come or pass over; to spreads over.
(v. i.) To gain the superiority; to be victorious.
Example Sentences:
(1) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(2) To overcome these problems we developed methotrexate bone cement (MTX-Palacos) with the aim to obtain high local concentrations of methotrexate in order to destroy remaining tumor cells and avoid systemic side effects.
(3) This phenomenon may be overcome by utilizing more dextran-coated charcoal in the extraction.
(4) The diet dilution technique overcomes the major disadvantage of the graded supplementation method for determining the requirements of amino acids, namely that of the amino acid balance changing systematically in successive dietary treatments.
(5) This was overcome by using a continuous subcutaneous infusion pump which also enabled the effective daily dosage to be reduced and thereby adverse reactions to be avoided.
(6) If this is the only issue, flight would be fine, but need to make sure that it isn’t symptomatic of a more significant upstream root cause.” Elon Musk (@elonmusk) Btw, 99% likely to be fine (closed loop TVC wd overcome error), but that 1% chance isn't worth rolling the dice.
(7) The model is meant to overcome the diffusional limitations, caused by a microcapsulated membrane.
(8) To overcome the problem of incontinence which failed to respond to standard measures, an animal model was designed for continent diversion without cystectomy.
(9) Results indicate that the rachitogenic factor in rye is not present in the ash portion of the grain, that it can be largely overcome by water extraction and penicillin supplementation, and that an organic solvent extraction has no effect.
(10) We interpret this exaggerated positive attitude as an attempt to overcome inner fears, doubts and ambivalences.
(11) In contrast, addition of CsA-plus-exogenous-IL-2 within the first 4 hr of culture did not overcome the immunosuppressive effect of CsA.
(12) Intraruminal sustained release devices largely overcome this problem and constitute the most important new technology.
(13) Many of the limitations of conventional diagnostic arthroscopy of the knee have been largely overcome through the development of techniques that permit manipulation of intra-articular structures through paired, coordinated entry sites.
(14) In an attempt to overcome some of these difficulties, the concept of excess mortality was suggested, which is independent of death cause diagnoses or coding routines, as well as of the rate of detection of non-fatal cancer.
(15) To overcome some of these problems it is suggested that an investigation of lay evaluation of health care should be carried out within a conceptual framework which incorporates the following elements.
(16) Introduction of D 600 of the perfusion medium reduced release of catecholamines in response to acetylcholine, and this reduction was overcome by raising calcium ion concentrations of the perfusion medium.
(17) To help overcome this problem, a stereoscopic slide-based auto-instructional program has been developed as a substitute for dissection.
(18) Unlike cycloheximide (CXM) which inhibits long-term memory by inhibiting ribosomal protein synthesis, AIB is non-effective when administered 10 min or more after learning, and its effect is overcome by the sodium pump stimulator diphenylhydantoin if the latter is administered 10 min or more after learning.
(19) Plasma membranes from activated T cells stimulated HIV production, suggesting cell contact induces factor(s) in monocytes to overcome latency.
(20) The results demonstrate the usefulness of polyacrylamide-gel electrophoresis to detect and overcome aggregation problems with membrane proteins and suggest that detergent mixtures in specific ratios may be useful in the purification of adenylate cyclase and other intrinsic membrane proteins.
Overflow
Definition:
(v. t.) To flow over; to cover woth, or as with, water or other fluid; to spread over; to inundate; to overwhelm.
(v. t.) To flow over the brim of; to fill more than full.
(v. i.) To run over the bounds.
(v. i.) To be superabundant; to abound.
(n.) A flowing over, as of water or other fluid; an inundation.
(n.) That which flows over; a superfluous portion; a superabundance.
(n.) An outlet for the escape of surplus liquid.
Example Sentences:
(1) Corticosterone (4 x 10(-5) M) did not alter the stimulation-evoked 3H-overflow at 1-30 Hz.
(2) Bilateral electromyographic recordings from the biceps brachii and brachialis demonstrated that the amount of excitation overflow in the nonactive limb is between 10 percent and 20 percent of the maximal intensity of activity measured in the exercised limb.
(3) Overflow curves in both regions could be described with similar kinetic parameters except for the Vmax, which in the nucleus accumbens was only 60% of that measured in the caudate-putamen.
(4) The effects of alpha-adrenoceptor agonists and antagonists on the electrically (slices) or potassium-evoked (synaptosomes) tritium overflow were studied.
(5) No difference was found for the inhibition by serotonin and the facilitation by metitepine of the evoked overflow and for the metitepine-induced shift of the concentration-response curve for serotonin to the right.
(6) However, higher doses of diltiazem (60 microM) reduced the tritium overflow elicited by RNS or Vt but enhanced that caused by KCl.
(7) The alpha 2-adrenoceptor agonist clonidine inhibited, whereas the alpha 2-adrenoceptor antagonist rauwolscine facilitated the stimulated overflow of [3H]NA.
(8) In contrast, in synaptosomes superfused with Ca(2+)-free Krebs-Henseleit solution containing 15 mM K+ throughout, ethanol did not affect the tritium overflow evoked by 2 min introduction of 75 microM Ca2+ into the superfusion fluid.
(9) Increased formation of hydroxyl free radicals (.OH) reflected by .OH adduct of salicylate in brain dialysate was demonstrated during the sustained (more than 2 hours) dopamine overflow elicited by 75 nmol of 1-methyl-4-phenyldihydropyridine (MPDP+) and 1-methyl-4-phenylpyridinium (MPP+) in the rat striatum.
(10) At 10 min there was an associated transient minor increase in NA overflow but at 20 and 30 min the overflow of NA, elevated as a result of anoxic perfusion, returned to pre-anoxic levels on the re-introduction of substrate and oxygen.
(11) Cocaine (3 x 10(-6) M) enhanced the 3H-overflow slightly at 1-30 Hz.
(12) The ratio between stimulation-evoked 3H-overflow and spontaneous 3H-outflow was the same for both amines at 3 Hz, while the ratio was higher for 3H-NA at 10 Hz.
(13) In vitro, yohimbine increased K+-stimulated overflow of endogenous NA in a dose-dependent fashion.
(14) In perfused mesenteric vasculatures from spontaneously hypertensive rats (SHR) and normotensive Wistar kyoto rats (WKY), the effects of captopril on the vascular responsiveness and norepinephrine overflow from the adrenergic nerve endings were examined.
(15) Ethanol inhibited the NMDA-evoked tritium overflow in a concentration-dependent manner.
(16) Noradrenaline overflow from and the potassium content of circumflex territory venous effluent was unchanged.
(17) N-methyl-D-aspartate (50-2000 microM) produced a concentration-dependent increase in [3H]norepinephrine overflow from cortical and hippocampal slices with no significant alteration of the response following chronic ethanol treatment.
(18) Exocytotic release: Electrical stimulation of the left stellate ganglion (12 Hz; 1 min) evoked a calcium-dependent overflow of noradrenaline and NPY, that was accompanied by a minor and prolonged increase in DOPEG overflow.
(19) Overflow was detected using chronoamperometry with electrochemically pretreated, Nafion-coated carbon fiber microelectrodes.
(20) Surrey’s fast-growing population, overflowing out of London, needs 13,000 new school places.