(1) Comparison of wild type and the mutant parD promoter sequences indicated that three short repeats are likely involved in the negative regulation of this promoter.
(2) In contrast to CcdB, the Kid protein of the ParD system induces RecA-dependent cleavage of the cI repressor of bacteriophage lambda very inefficiently or not at all.
(3) The rate of admissions to psychiatric hospitals of patients with primary alcohol-related diagnoses (PARD) has increased from 1971 to 1983 and they now account for 19.7% of all admissions.
(4) Since the parDE operon requires the presence of the parCBA operon for efficient stabilization under certain growth conditions, the potential role of multimer resolution in plasmid stabilization was tested by substituting the ColE1 cer site for the parCBA operon.
(5) The system, which we have called ParD, maps inside the 1.45-kb PstI-EcoRI fragment that is adjacent to the origin of replication of the plasmid.
(6) And then I read another article recently that I am coming and watch over your shoulder Pards.
(7) Both of these promoters are repressed by their own gene products in the same manner in all three bacteria tested, with ParA functioning as the primary repressor of p-parCBA and ParD functioning as the repressor of p-parD.
(8) The ParD protein appears to bind to one inverted repeat sequence, located between the -35 and -10 boxes of p-parD.
(9) In vitro mutagenesis with hydroxylamine of a ParD- miniderivative of R1, pAB174, yielded mutants that were less stable in the cell than pAB174.
(10) The deletion analysis further allowed a redefinition of the minimal functional region as 790 bp in length, consisting of the parD gene (243 bp) and its promoter as well as sequences downstream of parD.
(11) When I speak with Pards tomorrow he may see some other position that he wants to look better of or get a better player for that area.
(12) Determination of the 5' ends of ParD transcripts, revealed that the genes coding for these proteins are transcribed from a single promoter.
(13) While the cer site did function to resolve plasmid multimers, it was not sufficient to restore stabilization activity to the parDE operon under growth conditions that require the parCBA operon for plasmid stability.
(14) The phenotype of a recently-described mutant (OV6), conditionally defective in chromosome partitioning and septal positioning, was originally thought to be due to a new gene (parD) mapping at 88.4 min.
(15) Transcriptional fusions were used to show that parA, parB, and parC are combined in an operon, while parD constitutes a separate transcription unit.
(16) The stability determined by the systems ParD of plasmid R1 and Ccd of plasmid F is due to the concerted action of two proteins, a cytotoxin and an antagonist of this function.
(17) In this paper we report that CcdA and Kis proteins, the antagonists of the Ccd and ParD systems respectively, share significant sequence homologies at both ends.
(18) The proteins P10 and P12 have been shown to be gene products of a new stability system, ParD, of plasmid R1.
(19) We have now shown that, in addition to the parD mutation, OV6 carries a gyrAam mutation and that this mutation is probably responsible for the gross phenotype of the mutant.
(20) Two divergently arranged promoters located in the intercistronic region between parC and parD mediate transcription of these genes.
Part
Definition:
(n.) One of the portions, equal or unequal, into which anything is divided, or regarded as divided; something less than a whole; a number, quantity, mass, or the like, regarded as going to make up, with others, a larger number, quantity, mass, etc., whether actually separate or not; a piece; a fragment; a fraction; a division; a member; a constituent.
(n.) An equal constituent portion; one of several or many like quantities, numbers, etc., into which anything is divided, or of which it is composed; proportional division or ingredient.
(n.) A constituent portion of a living or spiritual whole; a member; an organ; an essential element.
(n.) A constituent of character or capacity; quality; faculty; talent; -- usually in the plural with a collective sense.
(n.) Quarter; region; district; -- usually in the plural.
(n.) Such portion of any quantity, as when taken a certain number of times, will exactly make that quantity; as, 3 is a part of 12; -- the opposite of multiple. Also, a line or other element of a geometrical figure.
(n.) That which belongs to one, or which is assumed by one, or which falls to one, in a division or apportionment; share; portion; lot; interest; concern; duty; office.
(n.) One of the opposing parties or sides in a conflict or a controversy; a faction.
(n.) A particular character in a drama or a play; an assumed personification; also, the language, actions, and influence of a character or an actor in a play; or, figuratively, in real life. See To act a part, under Act.
(n.) One of the different melodies of a concerted composition, which heard in union compose its harmony; also, the music for each voice or instrument; as, the treble, tenor, or bass part; the violin part, etc.
(n.) To divide; to separate into distinct parts; to break into two or more parts or pieces; to sever.
(n.) To divide into shares; to divide and distribute; to allot; to apportion; to share.
(n.) To separate or disunite; to cause to go apart; to remove from contact or contiguity; to sunder.
(n.) Hence: To hold apart; to stand between; to intervene betwixt, as combatants.
(n.) To separate by a process of extraction, elimination, or secretion; as, to part gold from silver.
(n.) To leave; to quit.
(v. i.) To be broken or divided into parts or pieces; to break; to become separated; to go asunder; as, rope parts; his hair parts in the middle.
(v. i.) To go away; to depart; to take leave; to quit each other; hence, to die; -- often with from.
(v. i.) To perform an act of parting; to relinquish a connection of any kind; -- followed by with or from.
(v. i.) To have a part or share; to partake.
(adv.) Partly; in a measure.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) We attribute this in part to early diagnosis by computed tomography (CT), but a contributory factor may be earlier referrals from country centres to a paediatric trauma centre and rapid transfer, by air or road, by medical retrieval teams.
(3) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(4) These results show that the pathogenic phenotypes of MCF viruses are dissociable from the thymotropic phenotype and depend, at least in part, upon the enhancer sequences.
(5) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(6) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(7) At operation, the tumour was identified and excised with part of the aneurysmal wall.
(8) However, ticks, which failed to finish their feeding and represent a disproportionately great part of the whole parasite's population, die together with them and the parasitic system quickly restores its stability.
(9) Muscle weakness and atrophy were most marked in the distal parts of the legs, especially in the gastrocnemius and soleus muscles, and then spread to the thighs and gluteal muscles.
(10) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(11) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(12) Results show diet, self-control and parts of insulin-therapy to be problematic treatment components.
(13) Further analysis with two other synthetic peptides (212Cys to 222Glu and Cys X 221Ile to 236Glu) indicated that the dodecapeptide Ile-Glu-Phe-Gln-Lys-Asn-Asn-Arg-Leu-Leu-Glu mimicked either the whole or a major part of the neutralization epitope.
(14) Schneiderlin, valued at an improbable £27m, and the currently injured Jay Rodriguez are wanted by their former manager Mauricio Pochettino at Spurs, but the chairman Ralph Krueger has apparently called a halt to any more outgoings, saying: “They are part of the core that we have decided to keep at Southampton.” He added: “Jay Rodriguez and Morgan Schneiderlin are not for sale and they will be a part of our club as we enter the new season.” The new manager Ronald Koeman has begun rebuilding by bringing in Dusan Tadic and Graziano Pellè from the Dutch league and Krueger said: “We will have players coming in, we will make transfers to strengthen the squad.
(15) Patrice Evra Evra Handed a five-match international ban for his part in the France squad’s mutiny against Raymond Domenech at the 2010 World Cup, it took Evra almost a year to force his way back in.
(16) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(17) The method is based on two-dimensional scanning photon absorptiometry on the distal part of the forearm.
(18) McDonald said cutting better deals with suppliers and improving efficiency as well as raising some prices had only partly offset the impact of sterling’s fall against the dollar.
(19) A strong block to the elongation of nascent RNA transcripts by RNA polymerase II occurs in the 5' part of the mammalian c-fos proto-oncogene.
(20) Anytime they feel parts of the Basic Law are not up to their current standards of political correctness, they will change it and tell Hong Kong courts to obey.