(a.) Having the power of entering, piercing, or pervading; sharp; subtile; penetrative; as, a penetrating odor.
(a.) Acute; discerning; sagacious; quick to discover; as, a penetrating mind.
Example Sentences:
(1) The penetration of (22)Na was not prevented by the presence of metabolic inhibitors or by 500 mm NaCl in the suspending medium.
(2) Content of cyclic nucleoside monophosphates was decreased in all the eye tissues in experimental toxico-allergic uveitis as well as penetration of cAMP into the fluid of anterior chamber of the eye.
(3) After four years of existence, many evaluations were able to show the qualities of this system regarding root canal penetration, cleaning and shaping.
(4) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(5) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(6) Thus, although ferric-enterochelin cannot penetrate the cell surface from outside, the complex that is formed within the envelope is transported normally into the cell.
(7) Major limitations of the conventional sperm penetration assay are the inability to assess several aspects of sperm function (zona binding and penetration) and the absence of human ovulatory products known to influence fertilization.
(8) The cercaria, microcercous in type, is liberated and actively penetrates a second terrestrial pulmonate where development to the free metacercarial stage takes place in the pericardial cavity.
(9) The incomplete penetrance of the neoplastic phenotype and the monoclonality of lymphoid tumors suggest that tumor formation in v-fps mice requires genetic or epigenetic events in addition to expression of the P130gag-fps protein-tyrosine kinase.
(10) All of these factors make morbidity and mortality associated with penetrating injuries low.
(11) The treatment led to decreased spinnbarkeit, arborization and sperum penetration in the cervical mucus.
(12) The penetration coefficient, determined by the surface tension, contact angle and viscosity, is a measure of the ability of a liquid to penetrate into a capillary space, such as interproximal regions, gingival pockets and pores.
(13) The rational surgical methods of treatment in 85 patients with suppurative hepatic echinococcosis penetrating into the abdomen cavity are presented.
(14) This apparent lack of centrosomal staining was not due to problems associated with penetration of the antibody probes, since staining adjacent to and within the centriolar cylinder was observed when phosphoprotein antigens recognized by the MPM-2 antibody were localized.
(15) Both types of oral cleft, cleft palate (CP) and cleft lip with or without CP (CLP), segregate in these families together with lower lip pits or fistulae in an autosomal dominant mode with high penetrance estimated to be K = .89 and .99 by different methods.
(16) Cefuzoname seems to be among the middle ranks of beta-lactam agents as far as penetration rate is concerned; however, when its potent antibacterial activity and broad spectrum are taken into account, the concentrations in CSF in patients with meningitis seem worth examining.
(17) The time of sperm penetration in the mouse eggs, however, was delayed for one-half to one hour when ejaculated sperm were used.
(18) Enzymatic lability does not, however, play as important a role as lipophilicity in the corneal and conjunctival penetration of cycloalkyl and aryl ester prodrugs.
(19) No infection threads were found to penetrate either root hairs or the nodule cells.
(20) Kinetic studies showed that significant inhibition of virus production occurred when the inhibitor was added to infected cultures up to 5 h after virus penetration.
Poignant
Definition:
(a.) Pricking; piercing; sharp; pungent.
(a.) Fig.: Pointed; keen; satirical.
Example Sentences:
(1) Totò was a legend in the Vesuvian city – a comedian of genius; poignant, mysterious.
(2) Fleeting though it may have been (he jetted off to New York this morning and is due in Toronto on Saturday), there was a poignant reason for his appearance: he was here to play a tribute set to Frankie Knuckles, the Godfather of house and one of Morales's closest friends, who died suddenly in March.
(3) One of the most poignant exchanges came when Tony was asked by @ juliangratton to sum up the last seven years of his life.
(4) The exercise yard is adorned with poignant children's paintings in response to school trips here.
(5) This double bind may be particularly poignant for grandparents in single mother families.
(6) This addition was particularly poignant as Andrew Jackson’s legacy includes the decision to sign the Indian Removal Act of 1830 , which gave the federal government power to expel Native American tribes from their land.
(7) This poignant letter, addressing Recep Tayyip Erdogan and written by one of the protesters in Istanbul's historic Taksim Square , was widely circulated on Turkey's social media.
(8) Treasure Island gives us an intense sense of place, and a poignant coming-of-age story full of moral ambiguity.
(9) Their songs ranged from the almost unbearably poignant ("Hand in Glove") to the frankly vulnerable ("How Soon is Now").
(10) The image of the France midfielder walking, head bowed, past the World Cup trophy is one of the more poignant in football history.
(11) The second series of BBC1’s hit drama Happy Valley ended on Tuesday night , bowing out in a wondrous blaze of confrontation, perceptive resolution and poignant revelation.
(12) Ed Miliband said: "This is a tragic and poignant reminder of the sacrifices made by our armed forces in serving our country with bravery and distinction."
(13) But the American author, already the recipient of the Man Booker International prize, the Pulitzer and the National Book award , said it was "particularly poignant for me to have gotten news of the award only a few weeks after the death of Carlos Fuentes, who received the award in 1994".
(14) A picture sits on each one of the chairs, decorated by poignant letters, orange flowers and gifts.
(15) Or perhaps we could focus on the relationship of Leia and Solo, now married, and there could be a heart-rendingly poignant study of their elderly existence together, rather like Michael Haneke's Amour , but set in space.
(16) Dern, all windblown white hair and stubble, is often entirely silent and withdrawn, and all the more compelling and poignant for that.
(17) On the basis of this limited but poignant experience, we propose an outline of steps in management to help others avoid similar problems.
(18) Yet the narratives in Benefits Street have a human and poignant quality, often presenting decent and compassionate people disenfranchised by an unfair society.
(19) Sandy Nairne, director of the NPG, said: "The Van Dyck self-portrait is a poignant portrait of great significance.
(20) It was poignant, afterwards, to hear Martínez try to put the human element into some perspective.