(a.) Having the power of entering, piercing, or pervading; sharp; subtile; penetrative; as, a penetrating odor.
(a.) Acute; discerning; sagacious; quick to discover; as, a penetrating mind.
Example Sentences:
(1) The penetration of (22)Na was not prevented by the presence of metabolic inhibitors or by 500 mm NaCl in the suspending medium.
(2) Content of cyclic nucleoside monophosphates was decreased in all the eye tissues in experimental toxico-allergic uveitis as well as penetration of cAMP into the fluid of anterior chamber of the eye.
(3) After four years of existence, many evaluations were able to show the qualities of this system regarding root canal penetration, cleaning and shaping.
(4) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(5) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(6) Thus, although ferric-enterochelin cannot penetrate the cell surface from outside, the complex that is formed within the envelope is transported normally into the cell.
(7) Major limitations of the conventional sperm penetration assay are the inability to assess several aspects of sperm function (zona binding and penetration) and the absence of human ovulatory products known to influence fertilization.
(8) The cercaria, microcercous in type, is liberated and actively penetrates a second terrestrial pulmonate where development to the free metacercarial stage takes place in the pericardial cavity.
(9) The incomplete penetrance of the neoplastic phenotype and the monoclonality of lymphoid tumors suggest that tumor formation in v-fps mice requires genetic or epigenetic events in addition to expression of the P130gag-fps protein-tyrosine kinase.
(10) All of these factors make morbidity and mortality associated with penetrating injuries low.
(11) The treatment led to decreased spinnbarkeit, arborization and sperum penetration in the cervical mucus.
(12) The penetration coefficient, determined by the surface tension, contact angle and viscosity, is a measure of the ability of a liquid to penetrate into a capillary space, such as interproximal regions, gingival pockets and pores.
(13) The rational surgical methods of treatment in 85 patients with suppurative hepatic echinococcosis penetrating into the abdomen cavity are presented.
(14) This apparent lack of centrosomal staining was not due to problems associated with penetration of the antibody probes, since staining adjacent to and within the centriolar cylinder was observed when phosphoprotein antigens recognized by the MPM-2 antibody were localized.
(15) Both types of oral cleft, cleft palate (CP) and cleft lip with or without CP (CLP), segregate in these families together with lower lip pits or fistulae in an autosomal dominant mode with high penetrance estimated to be K = .89 and .99 by different methods.
(16) Cefuzoname seems to be among the middle ranks of beta-lactam agents as far as penetration rate is concerned; however, when its potent antibacterial activity and broad spectrum are taken into account, the concentrations in CSF in patients with meningitis seem worth examining.
(17) The time of sperm penetration in the mouse eggs, however, was delayed for one-half to one hour when ejaculated sperm were used.
(18) Enzymatic lability does not, however, play as important a role as lipophilicity in the corneal and conjunctival penetration of cycloalkyl and aryl ester prodrugs.
(19) No infection threads were found to penetrate either root hairs or the nodule cells.
(20) Kinetic studies showed that significant inhibition of virus production occurred when the inhibitor was added to infected cultures up to 5 h after virus penetration.
Sharply
Definition:
(adv.) In a sharp manner,; keenly; acutely.
Example Sentences:
(1) Other haematological parameters remained normal, with the exception of the absolute number of lymphocytes, which initially fell sharply but soon returned to, and even exceeded, control levels.
(2) The overall incidence in patients over 50 years of age was 8.5%; it was more than twice as high in women (11.5%) as in men (4.5%) and rose sharply with age.
(3) The use of functional test with the ACTH administration demonstrated organic affection of the CNS to sharply aggravate the weakening and even the exhaustion of the functional reserves of the glomerular and the reticular zones of the adrenal cortex developing during thyrotoxicosis, and also the reserve possibilities of the sympathico-adrenal system.
(4) Mendl's candy colours contrast sharply with the gothic garb of our hero's enemies and the greys of the prison uniforms – as well as scenes showing the hotel later, in the 1960s, its opulence lost beneath a drab communist refurb.
(5) Polls indicated that anger over the government shutdown, which was sharply felt in parts of northern Virginia, as well as discomfort with Cuccinelli's deeply conservative views, handed the race to McAuliffe, a controversial Democratic fundraiser and close ally of Bill and Hillary Clinton.
(6) Computed tomography (CT) is the most sensitive radiologic study for detecting these tumors, which usually are small, round, sharply marginated, and of homogeneous soft tissue density.
(7) Infection level increased sharply in the age-group 6-10 years old among people residing far from the rivers.
(8) This contrasts sharply with the reduction in both the frequency and surface area of sensory neuron active zones that accompanies long-term habituation, and suggests that modulation of active zone number and size may be an anatomical correlate that lies in the long-term domain.
(9) This contrasted sharply with the markedly increased occurrences of anatomic abnormalities in these body regions of the sirenomelia and VATER patients.
(10) These findings contrast sharply with those of a similar study performed between 1969 and 1974.
(11) Apoptosis is a physiological mode of death where the dying cell plays an active part in its own demise, which contrasts sharply with what is seen in necrosis.
(12) Now, the position of King and Rosewell is essentially that, in the absence of the deficit reduction programme, the financial markets would lose confidence in Britain and interest rates on government debt would rise sharply.
(13) The competition comes a month after the Spanish government put forward legislation that aims to sharply limit women's access to abortion across the country.
(14) And the number has risen sharply since 1980, with nearly 1 billion people added to the ranks of the poor over the past 35 years.
(15) Under conditions of disturbed blood supply, irrespective of the method of anastomosing, the trophicity of tissues in the zone of suture is sharply disturbed.
(16) Examination of other potential inhibitors revealed a rank order of potency against calpain to be: peptidyl sulphonium methyl ketones > fluoromethyl ketones, diazomethyl ketones >> acyloxymethyl ketones, an order which differs sharply from that found for cathespin B.
(17) The treatment of hemangiomas with X-rays has been sharply criticized because of their tendency to involute spontaneously.
(18) In short – in the absence of a policy response – economic growth will slow sharply in the months ahead.
(19) In zero Ca2(+)-EGTA Ringer solution, the low residual MEPP frequency is independent of terminal length, even when MPP frequency is sharply increased by tetanic stimulation.
(20) The intracellular level of AdoHcy decreased sharply after the beginning of starvation reaching a value of 18% of that in vegative cells within 4 h. In contrast, there was a two-fold transient increase in AdoMet at the time of aggregation.