(v. t.) To disturb; to agitate; to vex; to trouble; to disquiet.
(v. t.) To disorder; to confuse.
Example Sentences:
(1) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(2) Ultraviolet difference spectrophotometry indicates that the inactivated enzyme retains its capacity for binding the nucleotide substrates whereas the spectral perturbation characteristic of 3-phosphoglycerate binding is abolished in the modified enzyme.
(3) It is suggested that laboratory experiments should be performed on perturbed systems only if simulations have shown that the methods of data analysis will be satisfactorily powerful and accurate.
(4) Thresholds were measured for detecting perturbations in a regular lattice of dots by modulating local dot density, local dot luminance, or some combination of the two.
(5) It is shown that when a constant current is applied such that a stable equilibrium and rhythmic firing are present, the following predictions are inherent in the HH system of equations: (a) Small instantaneous voltage perturbations to the axon given at points along its firing spike result in phase resetting curves (when new phase versus old phase is plotted) with an average slope of 1.
(6) Lower lip perturbation duration was manipulated to yield two different load conditions.
(7) The role of the Golgi complex in the post-translational oligosaccharide maturation of alpha-amylase was explored by use of the carboxylic ionophore, monensin (10(-7)M), a known perturbant of the structure and function of the Golgi complex.
(8) The importance of the ionic interaction due to the formation of the salt bridge between the Asp-27 and the pteridine ring in Escherichia coli dihydrofolate reductase-methotrexate complex has been studied by using the free-energy perturbation method.
(9) Presence of the monosynaptic reflex during platform perturbations at normal latencies suggests that balance problems in children with Down syndrome do not result from hypotonia, which researchers have defined as decreased segmental motoneuron pool excitability and pathology of stretch reflex mechanisms, but rather result from defects within higher level postural mechanisms.
(10) We have perturbed the dynamics of the nuclear lamins by means of cell fusion between mitotic and interphase cells and have studied redistribution of lamins in fused cells as a function of extracellular pH levels.
(11) In the coagulating gland, this compensatory response involved the proliferation of many cells which, in the absence of cytotoxic perturbation, would be non-proliferatie (Q cells).
(12) The effect of initial perturbation of the thrombus by a guide wire appears to be less important than the thrombus disruption and accelerated thrombolysis caused by the pulsatile delivery system.
(13) As before, subjects were instructed to either oppose the perturbation (Predictable Oppose) or relax the forearm muscles (Predictable Let-Go).
(14) Bivalent cations (Ca2+, UO2(2+) or Zn2+) in the subphase at pH 5.6 significantly modified the behaviour of mixed monolayers of fusogenic lipids with phospholipids; there was a parallel perturbing effect of fusogenic lipids on interactions between monolayers of phospholipids and bivalent cations.
(15) In particular, nitration of Tyr-51 provoked a structural perturbation in the globular region.
(16) Altering the biophysical characteristics of cell membranes by diet and membrane perturbing agents markedly influences thermosensitivity of cells.
(17) Paraphilias (PAs) and non-paraphilic sexual addictions (NPSAs) may be behaviors that share a common perturbation of central serotonin neuroregulation as a component of their pathophysiology.
(18) Two functions of these have been proposed: 1) that they are compatible osmolytes which regulate cell volume (against high external NaCl) without inhibiting proteins and 2) that methylamines (GPC and betaine) are counteracting osmolytes which stabilize proteins against perturbation from high renal urea.
(19) This high incidence of HER2 gene amplification with accompanying overexpression in non-invasive breast tumors suggests that perturbations of the HER2 oncogene are among the earliest and most common genetic lesions in human breast cancer.
(20) Hypophysectomy was selected as a model system for perturbing testicular cell types, since the cytological sequelae of this treatment post-hypophysectomy in the rat are well documented in the literature.
Trouble
Definition:
(v. t.) A fault or interruption in a stratum.
(v. t.) To put into confused motion; to disturb; to agitate.
(v. t.) To disturb; to perplex; to afflict; to distress; to grieve; to fret; to annoy; to vex.
(v. t.) To give occasion for labor to; -- used in polite phraseology; as, I will not trouble you to deliver the letter.
(a.) Troubled; dark; gloomy.
(v. t.) The state of being troubled; disturbance; agitation; uneasiness; vexation; calamity.
(v. t.) That which gives disturbance, annoyance, or vexation; that which afflicts.
Example Sentences:
(1) The patient was a forty-five-year-old female who had been troubled by obstinate Raynaud's phenomenon for ten years before the definite diagnosis of pulmonary hypertension was made.
(2) Based on a large, ongoing empirical research effort to determine factors associated with the successful community adjustment of troubled adolescents leaving residential treatment, this paper focuses on multiple indicators of success measured at multiple points of time in the treatment process.
(3) "The disrespect embodied in these apparent mass violations of the law is part of a larger pattern of seeming indifference to the constitution that is deeply troubling to millions of Americans in both political parties," he said.
(4) Its current troubles are in part due to the fact that Colt lost out on the M4 US army contract to FN Herstal in 2013.
(5) FC Terek Grozny, the newly energised team based in the troubled Caucasus republic of Chechnya , is hoping a slew of high-profile international acquisitions will help it make waves in the Russian premier league, which kicked off last weekend.
(6) The writer Palesa Morudu told me that she sees, in the South African pride that "we did it", a troubling anxiety that we can't: "Why are we celebrating that we built stadiums on time?
(7) They can genuinely believe their partner provoked them to commit the abuse, just so they could get them in trouble.
(8) Here's something else you've worked out: Anthony's name is made up, in order to stop my interviewee from getting in trouble with his employer, and I can't be too specific about his living arrangements.
(9) Perhaps strangely, it was the second remark that troubled me more than the possibility that humanity would be extinguished by my hand.
(10) Concerning the etio-pathogenic study, as we tried to show, the authors agree in simultaneous and contemporary appearance, between the 4th and the 6th month of the intra-uterine life of oculo-cerebro-renal troubles of Lowe's Syndrom and in the existence of a common factor, probably a genetic one.
(11) The very low number of African members is particularly troubling, because more than one third of projects take place in that region.
(12) "When people don't feel they have a reason to stay out of trouble, the consequences for communities can be devastating – as we saw last August," said Darra Singh, chair of the panel.
(13) Arvind Kejriwal, leader of a new populist political party "dedicated to improving the lot of the common man", announced on Monday that he would form a government to run the sprawling, troubled and increasingly wealthy city of 15 million people.
(14) While Brown – finally fit again after appalling knee trouble that very nearly ended his career –began a home game for the first time since January 2012, Poyet only found room in Sunderland's starting XI for five of the 14 summer signings secured by Roberto De Fanti, the club's director of football.
(15) Port Vale are in deep financial trouble and their administrators will not let him pay half the player's wages.
(16) Flying in Soyuz was “ real teamwork ” she said, adding: “Tim will have no trouble with that.” David Southwood , a senior researcher at Imperial College, and a member of the UK space agency steering board, has known Tim since he joined the European Space Agency in 2009.
(17) Last month Neil Berkett, Virgin Media's chief executive, said he was "not surprised" YouView had run into trouble, given the number of partners involved, adding that the cable company intended to "take advantage" of the delay.
(18) Britain’s troubled relationship with the EU has provided Boris Johnson with nothing but fun since he first made his name lampooning the federalist ambitions of Jacques Delors as the Daily Telegraph’s Brussels correspondent in the early 1990s .
(19) Mohammed Salama, 23, an Al Ahly ultra whose leg was broken in the stadium riot, said it became clear at half-time in the match between the two historical foes that trouble was brewing.
(20) They were compared to two groups: normal elderly subjects with no memory trouble and no attention dysfunction (12 subjects, mean age: 66) and elderly subjects with minor trouble in STM and little attention disturbance (6 subjects, mean age: 68.5).