(a.) Having spots and patches of black and white, or other colors; mottled; pied.
(a.) Fig.: Mixed.
Example Sentences:
(1) Male and female rats of the inbred Piebald Virol Glaxo ( PVG) and Sprague Dawley (SD) strains were infected with 20 metacercariae of Fasciola hepatica.
(2) Using DNA of a patient with piebaldism, mental retardation, and multiple congenital anomalies associated with a 46,XY,del(4) (q12q21.1) karyotype, we carried out quantitative Southern blot hybridization analyses of the KIT gene and the adjacent PDGFRA (platelet-derived growth factor receptor alpha subunit) genes.
(3) Seven piebald lethal (PLM) mice with histologically verified aganglionosis and seven normal littermates (NLM) were sacrificed.
(4) Effects of hypoxia and hypothermia on the poststimulus rebound contractile response (PSRR) were studied in the circular muscle coat of the large intestine of the piebald mouse model for Hirschsprung's disease.
(5) The authors describe peculiar tumors with brown-white piebald anterior surface, which had grown bilaterally from the corpora nigra (C.N.)
(6) Controls of Piebald Virol Glaxo, Wistar and DA rats were also employed.
(7) Two other frequent colours are white spotting, due to the piebald allele (sp), and the chinchilla allele (ch).
(8) The results indicate that the distended portion of the colon of piebald mice is capable of coordinated peristalsis and that accumulation of feces and megacolon are secondary to the terminal obstruction that results from absence of coordinated propulsive activity in the hypoganglionic terminal segment.
(9) It is concluded that cholinergic innervation is congenitally absent in the aganglionic rectum in piebald lethal mice.
(10) Significant histological and immunocytochemical differences were seen in the ganglionic segment of colon between piebald mice with early clinical onset of acute illness and piebald mice with late onset enterocolitis.
(11) Human piebaldism is an expression of neural crest component abnormality that is classically inherited dominantly and is probably heterogeneous genetically.
(12) Here, pigmented skin around the axilla was transplanted to hypomelanotic areas in two patients with piebaldism.
(13) Vitreous fluorophotometry was performed on pigmented male rats (Piebald strain) 2 weeks after induction of diabetes by streptozotocin.
(14) The experiments were conducted on bulls-analogs of the black-piebald and Simmental breed which differ from each other in the intensity of live weight gain (18-31%) as well as on lactating cows-analogs of the black-piebald breed which differ in the level of milk productivity (41-80%).
(15) In the muscles of bulls the activity of phosphoglucomutase, phosphohexoisomerase, aldolase and fructose-1,6-diphosphatase is considerably higher (except of the activity of phosphoglucomutase and phosphohexoisomerase in the muscles of pure-bred black-piebald animals for which difference is not statistically reliable) and the content of glycogen, glucose, fructose, lactic acid, free and phosphorylated pentoses of nonadenylic compounds is essentially lower than in the muscle tissue of heifers of analogous breed groups.
(16) Comparative study of achromic and normally pigmented skin of three piebald patients from two families is reported here.
(17) This same region also contains genes for two of the structurally related factors, for c-kit, a receptor for an as yet unidentified ligand, and for 'piebald trait', an inherited skin pigmentation disorder.
(18) The latency and duration of the PSRR were increased during hypothermia while the amplitude decreased in all ganglionated regions of large intestinal preparations from both piebald mice and their normal siblings.
(19) In the course of the investigation of piebald (black-white) cattle it is found that 17,62% animals produce the AA type beta-lactoglobulin, 49,52%--the AB type and 32,86%--the BB type.
(20) The similarities between piebaldism and the Waardenburg syndromes are discussed.
Variegated
Definition:
(imp. & p. p.) of Variegate
(a.) Having marks or patches of different colors; as, variegated leaves, or flowers.
Example Sentences:
(1) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
(2) Such characteristics are reminiscent of the behavior of variegating position-effects in Drosophila and the application of this paradigm to human disease phenotypes provides both a mechanism by which differential genome imprinting may be accomplished as well as genetic models that may explain the clinical association of syntenic diseases, the association between tumor progression and specific chromosomal aneuploidy and the unusual inheritance characteristics of many diseases.
(3) The diagnosis depends on fecal excretion of porphyrins, which is greatly increased in variegate porphyria and consists predominantly of protoporphyrin.
(4) Although clinical improvements occurred in the case of variegate porphyria, the results were inconclusive for reasons given.
(5) Appropriate laboratory tests on urine and feces samples are necessary to distinguish between PCTS and variegate porphyria when a young woman presents with the skin lesions characteristic of cutaneous hepatic porphyrias.
(6) One patient with variegate prophyria and two with hereditary coproporphyria had an attack related to pregnancy.
(7) The theory of the unconscious that arises from the method of direct interpretation reflects a differentiated inner world with variegated landscapes of images and frameworks.
(8) The faecal porphyrin patterns of 24 patients with porphyria cutanea tarda symptomatica (PCTS), eight patients with variegate porphyria, three patients with other types of porphyria, and 20 non-porphyrics subjects have been compared using a two-demensional thin layer chromatographic technique that separates porphyrins of the isocoproporphyrin series from other faecal porphyrins.
(9) A 62-year-old man with variegate porphyria is reported.
(10) Four patients with variegate porphyria (VP) were treated with repeated haem arginate infusions daily for 4 days and then weekly for 4 weeks.
(11) Hence, the differences in binding of the w+ gene probe in the variegating and variegation-suppressed strains reflect differences in chromosomal packaging rather than alterations in gene number.
(12) The lesions appeared brownish black, and most were variegated from tan to black.
(13) Thus, mice with variegating transgenes can provide molecular access to gene control mechanisms and to their consequences in development and disease.
(14) The results provide some indication as to the mechanism and timing for the general suppression of position-effect variegation by supernumerary heterochromatin in the genome.
(15) Beautiful and ancient plants, such as spreading bellflower , could become extinct in some places through the escape of variegated yellow archangel from gardens.
(16) Variegated endocrine cells were documented within this lining, using immunohistochemical and ultrastructural techniques.
(18) In white-mottled (wm) position-effect variegation mutants, a significant correlation was found between the extent of variegation (percentage of yellow cells) and riboflavin content (growth effect) of the MT.
(19) Four patients suffering from variegate prophyria were investigated during acute attacks.
(20) These changes include variegated hyperplasia of the pulp with epithelioid cells, mature eosinophilic granulocytes and immunoblasts occasionally resembling Hodgkin cells.