(v. t.) To press hard or squeeze between the ends of the fingers, between teeth or claws, or between the jaws of an instrument; to squeeze or compress, as between any two hard bodies.
(v. t.) o seize; to grip; to bite; -- said of animals.
(v. t.) To plait.
(v. t.) Figuratively: To cramp; to straiten; to oppress; to starve; to distress; as, to be pinched for money.
(v. t.) To move, as a railroad car, by prying the wheels with a pinch. See Pinch, n., 4.
(v. i.) To act with pressing force; to compress; to squeeze; as, the shoe pinches.
(v. i.) To take hold; to grip, as a dog does.
(v. i.) To spare; to be niggardly; to be covetous.
(n.) A close compression, as with the ends of the fingers, or with an instrument; a nip.
(n.) As much as may be taken between the finger and thumb; any very small quantity; as, a pinch of snuff.
(n.) Pian; pang.
(n.) A lever having a projection at one end, acting as a fulcrum, -- used chiefly to roll heavy wheels, etc. Called also pinch bar.
Example Sentences:
(1) produced a strong analgesic effect in the formalin test and in the tail pinch test.
(2) The observed clinical findings include scarring of the face and hands (83.7%), hyperpigmentation (65%), hypertrichosis (44.8%), pinched facies (40.1%), painless arthritis (70.2%), small hands (66.6%), sensory shading (60.6%), myotonia (37.9%), cogwheeling (41.9%), enlarged thyroid (34.9%), and enlarged liver (4.8%).
(3) Results indicate substantial postoperative improvement in tip prehension and grasp, while performance remained essentially unchanged for lateral prehension, pinch force, and power grip.
(4) To mimic physiological conditions, synaptosomes, which are pinched off presynaptic nerve termini, were used.
(5) Comparison with other pinch strength studies established that although force magnitudes may be strongly influenced by specific experimental conditions, empirical relationships among different pinch forces are fairly stable and predictable.
(6) Anyone still imagining that it was only the defender’s recovery from injury rather than his form that was preventing him from starting (and it’s been clear for a while that’s not the case) might have noted the coach’s instructions to Gonzalez to be ready to play a few minutes when needed, either as an extra defender or even in a pinch as an extra forward.
(7) He has just performed a skit now about his bicycle scheme, which included a swipe at the French (because their scheme resulted in many more cycles being pinched, apparently.)
(8) Other small endocytic vesicles pinch off from the surface, move deeper into the cytoplasm and fuse with the lateral plasmalemma; their protein content is emptied into the intercellular space by exocytosis.
(9) It is suggested that the optimal way to diagnose microsporidiosis is by light microscopical examination of duodenal pinch biopsy specimens.
(10) Numerous 70-mmicro diameter vesicles apparently pinch off from the Golgi systems, transport this material through the egg, and probably then fuse to form a crenate, membrane-limited yolk droplet.
(11) Analysis of the rate of functional recovery as measured by total active motion, gross grip strength, and pinch grip strength showed no significant difference between the two groups.
(12) Which is another reason why, independent of talent, an Argentine is more likely to make a successful go of life in Madrid, Milan, Manchester or at a pinch (as with the case of the winger Carlos Marinelli) Middlesbrough.
(13) The term "barons" hasn't really had any meaning since the Combination Act of 1799 ; at a pinch 1825 , when the legislation to prevent the activity of unions was passed again, in the Combination of Workmen Act.
(14) A temporary pinching off of the spermatic cord was carried out in 100 male Wistar rats in order to evaluate the effect of a limited period of ischaemia on the testicular parenchyma.
(15) It involved bringing in Kyle Beckerman alongside Jermaine Jones in the base of midfield and asking Jones to pinch in when necessary and get forward when possible.
(16) Neurons were first classified as on-cells if they fired faster during noxious pinch or as off-cells if they fired slower.
(17) The pinch technique has been found to be useful in repairing cosmetic eyelid deformities.
(18) It is proposed that pinch-induced immobility is mediated by both dopaminergic and cholinergic systems.
(19) In this article the concept of utilizing a pinched inlet channel for field-flow fractionation (FFF), in which the channel thickness is reduced over a substantial inlet segment to reduce relaxation effects and avoid stopflow, is evaluated for steric FFF using one conventional channel and two pinched inlet channels.
(20) Pharmacological analysis of the involvement of the brain catecholamines in tail-pinch behavior suggests that it is critically dependent on the nigrostriatal dopamine system.
Twitch
Definition:
(v. t.) To pull with a sudden jerk; to pluck with a short, quick motion; to snatch; as, to twitch one by the sleeve; to twitch a thing out of another's hand; to twitch off clusters of grapes.
(n.) The act of twitching; a pull with a jerk; a short, sudden, quick pull; as, a twitch by the sleeve.
(n.) A short, spastic contraction of the fibers or muscles; a simple muscular contraction; as, convulsive twitches; a twitch in the side.
(n.) A stick with a hole in one end through which passes a loop, which can be drawn tightly over the upper lip or an ear of a horse. By twisting the stick the compression is made sufficiently painful to keep the animal quiet during a slight surgical operation.
Example Sentences:
(1) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(2) Twitch-tetanus ratios were calculated and found not to be related to unit contraction time.6.
(3) Hyperosmolar buffer slightly increased the sensitivity and maximal response to methacholine as well as the cholinergic twitch to electric field stimulation.
(4) The present results suggest that TMB-8 blocks twitches by preventing the release of Ca++ ions bound to the intracellular surface of the t-tubular membrane which is often called the store of 'trigger-calcium' ions.
(5) The twitches elicited by 0.1 msec pulses were abolished by tetrodotoxin, but were not reduced by dimethyltubocurarine or by hexamethonium.
(6) Starting from the observation that the part above 6 Hz of the power spectrum of force tremor during isometric contractions can be related to the unfused twitches of motor units firing asynchronously, an attempt was made to study the usefulness of force tremor spectral analysis as a global descriptor of motoneurone pool activity.
(7) The soleus, deep portions of the vastus lateralis, and superficial portions of the vastus lateralis muscles were examined to represent slow-twitch-oxidative, fast-twitch-oxidative-glycolytic, and fast-twitch-glycolytic skeletal muscle fiber types, respectively.
(8) Epinephrine potentiates muscle twitches via the second messenger, cAMP, secondary to hormone binding to membrane-bound beta-receptors.
(9) In physiological studies CDS mimics clonidine's action as an inhibitor of the electrically induced twitch response and as a partial agonist of the epinephrine-induced platelet aggregation.
(10) Facial twitch was followed by the generalized convulsion, further progressing to trembling of the limbs and then kicking of the hindlimb (full seizure) after 55 days of age.
(11) Stimulating the dorsal root at L5 was found to produce hindleg twitches in EAE rats with complete hindlimb paralysis.
(12) The anesthesiologist assessed the degree of neuromuscular blockade intraoperatively prior to pharmacologic reversal either by the standard method of visually counting the number of evoked thumb twitches elicited by supramaximal train-of-four stimulation of the ulnar nerve (i.e., thumb train-of-four count), or by an alternative method such as 1) visually counting the number of evoked orbicularis oculi muscle twitches elicited by supramaximal train-of-four stimulation of the facial nerve, or 2) observing the patient for clinical evidence of partial recovery (e.g., swallowing or attempts to breathe).
(13) Measurements of mouth opening were made for up to 10 min after loss of the adductor pollicis twitch and cessation of muscle fasciculations.
(14) On the other hand, the lack of any twitch-potentiating effect by naloxone methylbromide, a quaternary derivative of naloxone, suggests that opioids which potentiate the twitch must enter the lipid phase of the membrane to act.
(15) The relaxant effect of catecholamines on the twitch is temperature and rate dependent.
(16) Disopyramide 5 X 10(-5) - 10(-3) mol litre-1 produced a concentration-dependent reduction of twitch amplitude in the indirectly stimulated chick biventer cervicis preparation, but greater concentrations were required to reduce twitches elicited directly in the presence of erabutoxin-b 1 microgram ml-1.
(17) The pigeon's metapatagialis muscle consists of three slips, two twitch and one tonic, and these slips are distinguishable at the gross anatomical level.
(18) There was a good correlation between the two methods of measurement for both twitch height and train-of-four ratio (correlation coefficients 0.93 and 0.97, respectively).
(19) Head twitches induced by 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) could be abolished by low doses of RP 62203 in mice (ED50 = 0.44 mg kg-1, p.o.)
(20) Chronic stimulation of the denervated SOL resulted in twitch times-to-peak and half-relaxation times that varied in a graded manner between values longer than those in the normal SOL to values as fast as those in the normal EDL, depending upon the pattern used.