(n.) A large cavity or hole in the ground, either natural or artificial; a cavity in the surface of a body; an indentation
(n.) The shaft of a coal mine; a coal pit.
(n.) A large hole in the ground from which material is dug or quarried; as, a stone pit; a gravel pit; or in which material is made by burning; as, a lime pit; a charcoal pit.
(n.) A vat sunk in the ground; as, a tan pit.
(n.) Any abyss; especially, the grave, or hades.
(n.) A covered deep hole for entrapping wild beasts; a pitfall; hence, a trap; a snare. Also used figuratively.
(n.) A depression or hollow in the surface of the human body
(n.) The hollow place under the shoulder or arm; the axilla, or armpit.
(n.) See Pit of the stomach (below).
(n.) The indentation or mark left by a pustule, as in smallpox.
(n.) Formerly, that part of a theater, on the floor of the house, below the level of the stage and behind the orchestra; now, in England, commonly the part behind the stalls; in the United States, the parquet; also, the occupants of such a part of a theater.
(n.) An inclosed area into which gamecocks, dogs, and other animals are brought to fight, or where dogs are trained to kill rats.
(n.) The endocarp of a drupe, and its contained seed or seeds; a stone; as, a peach pit; a cherry pit, etc.
(n.) A depression or thin spot in the wall of a duct.
(v. t.) To place or put into a pit or hole.
(v. t.) To mark with little hollows, as by various pustules; as, a face pitted by smallpox.
(v. t.) To introduce as an antagonist; to set forward for or in a contest; as, to pit one dog against another.
Example Sentences:
(1) When compared with nonspecialized regions of the cell membranes, these contact sites were characterized by a decreased intercellular distance, subplasmalemmal densities and coated pits.
(2) Interaction of viable macrophages with cationic particles at 37 degrees C resulted in their "internalization" within vesicles and coated pits and a closer apposition between many segments of plasmalemma than with neutral or anionic substances.
(3) Both types of oral cleft, cleft palate (CP) and cleft lip with or without CP (CLP), segregate in these families together with lower lip pits or fistulae in an autosomal dominant mode with high penetrance estimated to be K = .89 and .99 by different methods.
(4) The potential use of ancrod, a purified isolate from the venom of the Malaysian pit viper, Agkistrodon rhodostoma, in decreasing the frequency of cyclic flow variations in severely stenosed canine coronary arteries and causing thrombolysis of an acute coronary thrombus induced by a copper coil was evaluated.
(5) On land, the pits' stagnant pools of water become breeding grounds for dengue fever and malaria.
(6) Demonstration of low levels of Pit-1 expression in Ames dwarf (df) mice implies that both Pit-1 and df expression may be required for pituitary differentiation.
(7) At 4 degrees C or after fixation, anti-renal tubular brush border vesicle (BBV) IgG bound diffusely to the surface of GEC and to coated pits.
(8) A cell with a large Golgi apparatus and associated cytoplasmic granules resembles the pit cell described in the liver of a few other vertebrates.
(9) Pitting corrosion was seen on low-resistant Ni-Cr alloys, which had less Cr content.
(10) This brings lads like 12-year-old Matthew Mason down from the magnificent studio his father Mark, from a coal-mining town ravaged by pit closures, lovingly built him in the back garden at Gants Hill, north-east London.
(11) Stonehenge stood at the heart of a sprawling landscape of chapels, burial mounds, massive pits and ritual shrines, according to an unprecedented survey of the ancient grounds.
(12) Freeze fracture analysis confirmed the integrity of the tight junctions as well as increased numbers of vesicles or pits along the lateral cell membrane, indicating increased endocytotic activity.
(13) Likewise, the cost of emptying these pits can be high.
(14) Bifid uvula, preauricular pits, and abnormal palmar creases were also slightly more common in the patients, but the differences were not statistically significant.
(15) Hypertrophic fibrous astrocytes were common in chronic active lesions, were capable of myelin degradation and on occasion, contained myelin debris attached to clathrin-coated pits.
(16) A mother and daughter both presented at age 5 years with the triad of right-sided congenital cholesteatoma, right preauricular pits, and bilateral sensorineural hearing loss.
(17) In addition, the perfusion method in this experiment suggested the possibility of distinguishing pinocytotic vesicles from pits of cell membranes.
(18) Performance pay pitting teachers against each other just does not work - we are not in favour of that,” Merlino said.
(19) Both larval stages had an inner circle of 6 labial papillae, an outer circle of 6 labial papillae and 4 somatic papillae, and lateral amphidial pits.
(20) The country’s other attractions include a burning pit at “the door to hell” in the Darvaza crater, and rarely seen stretches of the silk road, the region’s ancient trade route.
Pith
Definition:
(n.) The soft spongy substance in the center of the stems of many plants and trees, especially those of the dicotyledonous or exogenous classes. It consists of cellular tissue.
(n.) The spongy interior substance of a feather.
(n.) The spinal cord; the marrow.
(n.) Hence: The which contains the strength of life; the vital or essential part; concentrated force; vigor; strength; importance; as, the speech lacked pith.
(v. t.) To destroy the central nervous system of (an animal, as a frog), as by passing a stout wire or needle up and down the vertebral canal.
Example Sentences:
(1) Finally, fosinopril had no effect on the pressor or chronotropic effects of norepinephrine (NE) or 1,1-dimethyl-4-phenylpiperinium (DMPP) or electrical stimulation of the sympathetic ganglia of pithed rats.
(2) Relatively weaker GUS activity was also detected in pith parenchyma.
(3) Both d- and l-amphetamine were also compared for their pressor and tachycardic activity in pithed rats.
(4) Intravenous administration of T-2 to pithed rats did not alter blood pressure or heart rate at a time when, in conscious rats, both blood pressure and heart rate were increased.
(5) Monoiodo-Ang II was found to be a potent, full agonist in in vivo bioassays and a more potent (2.5-fold) pressor agent than the native hormone Ang II in the pithed rat.
(6) APP 201-533 [3-amino-6-methyl-5-phenyl-2(1H)-pyridinone] was investigated in vivo in anesthetized and unanesthetized dogs and pithed open-chest cats and in vitro in guinea pig atria and papillary muscles, skinned muscle fibers from pig hearts, and rat myocardium.
(7) The effects of quinpirole, a specific dopamine DA2 receptor agonist, on autonomic nervous control of heart rate, were studied in normotensive pithed rats, by analysing its action on the tachycardia and bradycardia evoked by electrical stimulation of the cardioaccelerator (10 V; 1 ms; 0.5, 1, 3, 6 Hz) and vagus (10 V; 1 ms; 3, 6, 9 Hz) nerves respectively.
(8) Pith cells can shift from the C- to the C+ state by a process known as habituation.
(9) The pressor actions of ET3 and arginine vasopressin (AVP) were compared with one another in pithed rats in the presence of the calcium channel activator BAY K 8644 or the calcium channel antagonist nifedipine i.a.
(10) Both human endothelin 1 (ET1) and rat endothelin 3 (ET3) produced dose-dependent pressor effects in the pithed rat.
(11) Viprostol did not antagonize the tachycardia induced by stimulation of the discrete segments at C7-T1 (cardio-accelerator) of the spinal cord in pithed SHR, suggesting that viprostol did not activate the presynaptic alpha-adrenoceptors.
(12) In pithed rats, the vasopressor response to dihydroergotoxine was reduced competitively by yohimbine, and non-competitively by nifedipine, but not by prazosin or methysergide, showing that the vasoconstriction is mediated by alpha 2-adrenoceptors.
(13) The antagonistic effects of a new inositol phosphate derivative, D-myoinositol-1,2,6-trisphosphate (PP56), on pressor responses to preganglionic sympathetic nerve stimulation and exogenously administered phenylephrine or neuropeptide Y (NPY) were investigated in vivo in the pithed rat.
(14) We conclude that in contrast to the increase in diastolic pressure elicited by B-HT 920, calcium channels are not involved in the cirazoline-induced pressor responses in the pithed cat.
(15) Acute or chronic adrenalectomy did not alter the pressor responses and chronotropic effect of angiotensin in the pithed rat.
(16) Habituated cells derived from inducible pith cells give rise to normal plants whose leaf and pith tissues require cytokinin for growth in culture.
(17) The endovenous perfusion of the splenic material in acidified and alkalinized forms caused significant increases of the mean blood pressure in normal, vagotomized and pithed rats, showing that, in contradiction to previous reports, changes in pH did not affect its hypertensive activity.
(18) The dose-response curves of three alpha-agonists noradrenaline, St 587 and B-HT 933 in pithed rats were shifted rightwards by pretreatment (i.v.
(19) In pithed rats, only pindolol produced a definite fall of blood pressure.
(20) The bradycardia was reduced but not blocked by pre-treatment with guanethidine, yohimbine, propranolol or pithing.