(n.) The soft spongy substance in the center of the stems of many plants and trees, especially those of the dicotyledonous or exogenous classes. It consists of cellular tissue.
(n.) The spongy interior substance of a feather.
(n.) The spinal cord; the marrow.
(n.) Hence: The which contains the strength of life; the vital or essential part; concentrated force; vigor; strength; importance; as, the speech lacked pith.
(v. t.) To destroy the central nervous system of (an animal, as a frog), as by passing a stout wire or needle up and down the vertebral canal.
Example Sentences:
(1) Finally, fosinopril had no effect on the pressor or chronotropic effects of norepinephrine (NE) or 1,1-dimethyl-4-phenylpiperinium (DMPP) or electrical stimulation of the sympathetic ganglia of pithed rats.
(2) Relatively weaker GUS activity was also detected in pith parenchyma.
(3) Both d- and l-amphetamine were also compared for their pressor and tachycardic activity in pithed rats.
(4) Intravenous administration of T-2 to pithed rats did not alter blood pressure or heart rate at a time when, in conscious rats, both blood pressure and heart rate were increased.
(5) Monoiodo-Ang II was found to be a potent, full agonist in in vivo bioassays and a more potent (2.5-fold) pressor agent than the native hormone Ang II in the pithed rat.
(6) APP 201-533 [3-amino-6-methyl-5-phenyl-2(1H)-pyridinone] was investigated in vivo in anesthetized and unanesthetized dogs and pithed open-chest cats and in vitro in guinea pig atria and papillary muscles, skinned muscle fibers from pig hearts, and rat myocardium.
(7) The effects of quinpirole, a specific dopamine DA2 receptor agonist, on autonomic nervous control of heart rate, were studied in normotensive pithed rats, by analysing its action on the tachycardia and bradycardia evoked by electrical stimulation of the cardioaccelerator (10 V; 1 ms; 0.5, 1, 3, 6 Hz) and vagus (10 V; 1 ms; 3, 6, 9 Hz) nerves respectively.
(8) Pith cells can shift from the C- to the C+ state by a process known as habituation.
(9) The pressor actions of ET3 and arginine vasopressin (AVP) were compared with one another in pithed rats in the presence of the calcium channel activator BAY K 8644 or the calcium channel antagonist nifedipine i.a.
(10) Both human endothelin 1 (ET1) and rat endothelin 3 (ET3) produced dose-dependent pressor effects in the pithed rat.
(11) Viprostol did not antagonize the tachycardia induced by stimulation of the discrete segments at C7-T1 (cardio-accelerator) of the spinal cord in pithed SHR, suggesting that viprostol did not activate the presynaptic alpha-adrenoceptors.
(12) In pithed rats, the vasopressor response to dihydroergotoxine was reduced competitively by yohimbine, and non-competitively by nifedipine, but not by prazosin or methysergide, showing that the vasoconstriction is mediated by alpha 2-adrenoceptors.
(13) The antagonistic effects of a new inositol phosphate derivative, D-myoinositol-1,2,6-trisphosphate (PP56), on pressor responses to preganglionic sympathetic nerve stimulation and exogenously administered phenylephrine or neuropeptide Y (NPY) were investigated in vivo in the pithed rat.
(14) We conclude that in contrast to the increase in diastolic pressure elicited by B-HT 920, calcium channels are not involved in the cirazoline-induced pressor responses in the pithed cat.
(15) Acute or chronic adrenalectomy did not alter the pressor responses and chronotropic effect of angiotensin in the pithed rat.
(16) Habituated cells derived from inducible pith cells give rise to normal plants whose leaf and pith tissues require cytokinin for growth in culture.
(17) The endovenous perfusion of the splenic material in acidified and alkalinized forms caused significant increases of the mean blood pressure in normal, vagotomized and pithed rats, showing that, in contradiction to previous reports, changes in pH did not affect its hypertensive activity.
(18) The dose-response curves of three alpha-agonists noradrenaline, St 587 and B-HT 933 in pithed rats were shifted rightwards by pretreatment (i.v.
(19) In pithed rats, only pindolol produced a definite fall of blood pressure.
(20) The bradycardia was reduced but not blocked by pre-treatment with guanethidine, yohimbine, propranolol or pithing.
Shola
Definition:
(n.) See Sola.
Example Sentences:
(1) The 24-year-old becomes Alan Pardew’s fifth signing of the summer and offers much-needed support up front after the departures of the loan signing Loic Rémy and the out-of-contract Shola Ameobi.
(2) Victor Moses is coming off and Shola Ameobi is coming on.
(3) Newcastle manager Alan Pardew made just one change, bringing back Shola Ameobi up front at the expense of Vurnon Anita.
(4) And if all else fails, we could be about to witness Carl Cort's Kieran Gibbs' Shola Ameobi's World Cup debut.
(5) Shola Obadeyu wore a heavy duffel coat while queueing in Heathrow for a flight back to her sweltering home city of Abuja.
(6) Bolton’s Shola Ameobi ends drought as Steve Evans’ Leeds earn a point Read more Elsewhere in west London, another dark, gloomy cloud was lifted from over another wilting manager.
(7) Championship Shola Ameobi’s first goal in a little more than 17 months was not enough to lift his new club, Bolton Wanderers , off the foot of the table.
(8) With Pardew having introduced Shola Ameobi as Newcastle switched to 4-4-2, Stoke conceded a rather soft second goal when Yoan Gouffran shot assuredly into the bottom corner after Sorensen failed to cope with a Ben Arfa cross dispatched after the ball looked to have drifted momentarily out of play.
(9) In our fieldwork at the Shola Trust we’ve found that even people who have had family killed usually see it as an accident, and don’t hold a grudge against the elephants.
(10) Shola Ameobi comes on for Cisse, while Tevez departs to make way for Lescott.
(11) Even the introduction of Shola Ameobi, dubbed the "Mackem Slayer" in these parts because of his potent scoring record against Sunderland, could not change the sway of this match.
(12) "I would love it if Shola scored at the world cup," says Joseph Dixon.
(13) Shola Amamobi [Ameobi] is getting better and better, he's a young kid.
(15) 9.18pm BST 60 min: Shola Ameobi at the World Cup, though.
(16) Photograph: Shola Trust While most of the early research on HEC focused on quantifying the economic and other losses that people suffered, much of the newer work argues that what is more important is perceived loss.
(17) Shola Ameobi (Newcastle) Ameobi is dismissed by Phil Dowd, so Newcastle's afternoon is now collapsing in perhaps familiar fashion.
(19) Referee: Phil Dowd (Staffordshire) Shola starting is the most deflating news possible to have.
(20) When Moussa Sissoko's long legs swept him up the right wing they initiated a move that concluded with Shola Ameobi heading his fine cross home at the far post.