(n.) The soft spongy substance in the center of the stems of many plants and trees, especially those of the dicotyledonous or exogenous classes. It consists of cellular tissue.
(n.) The spongy interior substance of a feather.
(n.) The spinal cord; the marrow.
(n.) Hence: The which contains the strength of life; the vital or essential part; concentrated force; vigor; strength; importance; as, the speech lacked pith.
(v. t.) To destroy the central nervous system of (an animal, as a frog), as by passing a stout wire or needle up and down the vertebral canal.
Example Sentences:
(1) Finally, fosinopril had no effect on the pressor or chronotropic effects of norepinephrine (NE) or 1,1-dimethyl-4-phenylpiperinium (DMPP) or electrical stimulation of the sympathetic ganglia of pithed rats.
(2) Relatively weaker GUS activity was also detected in pith parenchyma.
(3) Both d- and l-amphetamine were also compared for their pressor and tachycardic activity in pithed rats.
(4) Intravenous administration of T-2 to pithed rats did not alter blood pressure or heart rate at a time when, in conscious rats, both blood pressure and heart rate were increased.
(5) Monoiodo-Ang II was found to be a potent, full agonist in in vivo bioassays and a more potent (2.5-fold) pressor agent than the native hormone Ang II in the pithed rat.
(6) APP 201-533 [3-amino-6-methyl-5-phenyl-2(1H)-pyridinone] was investigated in vivo in anesthetized and unanesthetized dogs and pithed open-chest cats and in vitro in guinea pig atria and papillary muscles, skinned muscle fibers from pig hearts, and rat myocardium.
(7) The effects of quinpirole, a specific dopamine DA2 receptor agonist, on autonomic nervous control of heart rate, were studied in normotensive pithed rats, by analysing its action on the tachycardia and bradycardia evoked by electrical stimulation of the cardioaccelerator (10 V; 1 ms; 0.5, 1, 3, 6 Hz) and vagus (10 V; 1 ms; 3, 6, 9 Hz) nerves respectively.
(8) Pith cells can shift from the C- to the C+ state by a process known as habituation.
(9) The pressor actions of ET3 and arginine vasopressin (AVP) were compared with one another in pithed rats in the presence of the calcium channel activator BAY K 8644 or the calcium channel antagonist nifedipine i.a.
(10) Both human endothelin 1 (ET1) and rat endothelin 3 (ET3) produced dose-dependent pressor effects in the pithed rat.
(11) Viprostol did not antagonize the tachycardia induced by stimulation of the discrete segments at C7-T1 (cardio-accelerator) of the spinal cord in pithed SHR, suggesting that viprostol did not activate the presynaptic alpha-adrenoceptors.
(12) In pithed rats, the vasopressor response to dihydroergotoxine was reduced competitively by yohimbine, and non-competitively by nifedipine, but not by prazosin or methysergide, showing that the vasoconstriction is mediated by alpha 2-adrenoceptors.
(13) The antagonistic effects of a new inositol phosphate derivative, D-myoinositol-1,2,6-trisphosphate (PP56), on pressor responses to preganglionic sympathetic nerve stimulation and exogenously administered phenylephrine or neuropeptide Y (NPY) were investigated in vivo in the pithed rat.
(14) We conclude that in contrast to the increase in diastolic pressure elicited by B-HT 920, calcium channels are not involved in the cirazoline-induced pressor responses in the pithed cat.
(15) Acute or chronic adrenalectomy did not alter the pressor responses and chronotropic effect of angiotensin in the pithed rat.
(16) Habituated cells derived from inducible pith cells give rise to normal plants whose leaf and pith tissues require cytokinin for growth in culture.
(17) The endovenous perfusion of the splenic material in acidified and alkalinized forms caused significant increases of the mean blood pressure in normal, vagotomized and pithed rats, showing that, in contradiction to previous reports, changes in pH did not affect its hypertensive activity.
(18) The dose-response curves of three alpha-agonists noradrenaline, St 587 and B-HT 933 in pithed rats were shifted rightwards by pretreatment (i.v.
(19) In pithed rats, only pindolol produced a definite fall of blood pressure.
(20) The bradycardia was reduced but not blocked by pre-treatment with guanethidine, yohimbine, propranolol or pithing.
Soul
Definition:
(a.) Sole.
(a.) Sole.
(v. i.) To afford suitable sustenance.
(n.) The spiritual, rational, and immortal part in man; that part of man which enables him to think, and which renders him a subject of moral government; -- sometimes, in distinction from the higher nature, or spirit, of man, the so-called animal soul, that is, the seat of life, the sensitive affections and phantasy, exclusive of the voluntary and rational powers; -- sometimes, in distinction from the mind, the moral and emotional part of man's nature, the seat of feeling, in distinction from intellect; -- sometimes, the intellect only; the understanding; the seat of knowledge, as distinguished from feeling. In a more general sense, "an animating, separable, surviving entity, the vehicle of individual personal existence."
(n.) The seat of real life or vitality; the source of action; the animating or essential part.
(n.) The leader; the inspirer; the moving spirit; the heart; as, the soul of an enterprise; an able general is the soul of his army.
(n.) Energy; courage; spirit; fervor; affection, or any other noble manifestation of the heart or moral nature; inherent power or goodness.
(n.) A human being; a person; -- a familiar appellation, usually with a qualifying epithet; as, poor soul.
(n.) A pure or disembodied spirit.
(v. t.) To indue with a soul; to furnish with a soul or mind.
Example Sentences:
(1) Some parents are blessed with a soul that lights up every time their little precious brings them a carefully crafted portrait or home-made greetings card.
(2) When the election comes, we won’t be campaigning for a coalition... ...we will be fighting heart and soul for a majority Conservative Government – because that is what our country needs.
(3) Much less obvious – except in the fictional domain of the C Thomas Howell film Soul Man – is why someone would want to “pass” in the other direction and voluntarily take on the weight of racial oppression.
(4) I approached the public inquiry after much soul-searching, weighing up the ramifications of "rocking the boat" with the potential longer-term gains of a more robust and sustainable regulator.
(5) "They are soul-less creatures pandering to the NRA ."
(6) Bloody odd combination but those Orange Foam Headphones would blast those magnificent records into my developing brain over and over again" chernypyos – Björk's Human Behavior and Sinead O'Connor's Fire On Babylon: "bjork's 'human behavior' and sinead o'connor's "fire on babylon" oddly stick in my head from that one evening walking in the woods, breathing the damp air, and feeling pleasantly invisible" Pyromancer – REM – Automatic for the People Blood Sugar Sex Magic Pearl Jam - Vs RATM's first album Portishead Maxinquaye by Tricky Manic Street Preachers – Gold Against the Soul Smashing Pumpkins, Siamese Dream "I used to go to the local library and take out a CD (50p for 3 weeks!
(7) This week, after much soul-searching, she is packing up her house to move to Shropshire so that “my mum can look after me”.
(8) It rips at our souls every single time we look the results,” said Winters, who was paid $12.8m, including a $10m buy-out award .
(9) Despite the spring-heeled bounce in their hair-raising hardcore storm – and their productive affair with Funkmaster George Clinton – the Peppers’ soul stew remains predominantly, ragingly punky.
(10) His collection of poems Beware Soul Brother (1971) and the volume of short stories Girls at War and Other Stories (1972) drew on the experiences of the war.
(11) London's future-soul act Jungle are new at No 7, with another big chart entry for the classic metal act Judas Priest.
(12) Civilised yet unsubdued, it serves as a visual analogy for the soul of man under socialism.
(13) Her work has taught her not only about people’s capacity for survival, she says, but also about the darkness of the human soul.
(14) The 32 dead souls ringing the Dr Strangelove war room of the NFL ownership meeting interrupt their Randroid tongue-bathing only to squeal like scalded truffle pigs at the thought of any power devolving to the actual people whose ability, knowledge and gameplay make the NFL worth watching in the first place.
(15) I was astonished as politics had never played a part in my time as a governor, but after some soul searching over the weekend and not wishing to cause the school any further issues I tendered my resignation, which she accepted.” Eskdale School said it did not wish to comment on the matter, but the remaining governors are investigating the circumstances surrounding Ward’s resignation.
(16) Saying Robinson’s death made him heartsick, Reverend Alexander Gee Jr, pastor of the Fountain of Life church, recommended a soul-searching analysis.
(17) Warm words from Obama for Biden leave door open for support for 2016 run Read more The US vice-president, in a conference call with Democratic National Committee members, said he was trying to decide whether he could give “my whole heart and my whole soul” to a run for the White House, but also alluded to the burden that had been placed on his family by the death of his son, Beau Biden .
(18) She said she was sorry that she would not see the “great lives” her children would make for themselves, adding: “But if you have a little spirituality you must believe I will be watching.” Bellingham continued: “Hopefully, I have taught you to aspire to things in life and it isn’t all about money - it is what is in your soul.” Referring to her decision end chemotherapy, Bellingham said: “I know you boys will feel upset and probably cross and go through a cross part with me but you have to respect my decision.
(19) It’s all well and good standing in a gallery and stroking your chin, but if you cast your eyes to the left and summon the concentration it takes to read the little rectangle of artistic blurb next to it, all of that context and explanation really helps transform that weird bit of twisted wire your kid could make into something deep and primal pulled from the soul.
(20) In some fundamental way, the company believed she held the keys to their soul.