(n.) The soft spongy substance in the center of the stems of many plants and trees, especially those of the dicotyledonous or exogenous classes. It consists of cellular tissue.
(n.) The spongy interior substance of a feather.
(n.) The spinal cord; the marrow.
(n.) Hence: The which contains the strength of life; the vital or essential part; concentrated force; vigor; strength; importance; as, the speech lacked pith.
(v. t.) To destroy the central nervous system of (an animal, as a frog), as by passing a stout wire or needle up and down the vertebral canal.
Example Sentences:
(1) Finally, fosinopril had no effect on the pressor or chronotropic effects of norepinephrine (NE) or 1,1-dimethyl-4-phenylpiperinium (DMPP) or electrical stimulation of the sympathetic ganglia of pithed rats.
(2) Relatively weaker GUS activity was also detected in pith parenchyma.
(3) Both d- and l-amphetamine were also compared for their pressor and tachycardic activity in pithed rats.
(4) Intravenous administration of T-2 to pithed rats did not alter blood pressure or heart rate at a time when, in conscious rats, both blood pressure and heart rate were increased.
(5) Monoiodo-Ang II was found to be a potent, full agonist in in vivo bioassays and a more potent (2.5-fold) pressor agent than the native hormone Ang II in the pithed rat.
(6) APP 201-533 [3-amino-6-methyl-5-phenyl-2(1H)-pyridinone] was investigated in vivo in anesthetized and unanesthetized dogs and pithed open-chest cats and in vitro in guinea pig atria and papillary muscles, skinned muscle fibers from pig hearts, and rat myocardium.
(7) The effects of quinpirole, a specific dopamine DA2 receptor agonist, on autonomic nervous control of heart rate, were studied in normotensive pithed rats, by analysing its action on the tachycardia and bradycardia evoked by electrical stimulation of the cardioaccelerator (10 V; 1 ms; 0.5, 1, 3, 6 Hz) and vagus (10 V; 1 ms; 3, 6, 9 Hz) nerves respectively.
(8) Pith cells can shift from the C- to the C+ state by a process known as habituation.
(9) The pressor actions of ET3 and arginine vasopressin (AVP) were compared with one another in pithed rats in the presence of the calcium channel activator BAY K 8644 or the calcium channel antagonist nifedipine i.a.
(10) Both human endothelin 1 (ET1) and rat endothelin 3 (ET3) produced dose-dependent pressor effects in the pithed rat.
(11) Viprostol did not antagonize the tachycardia induced by stimulation of the discrete segments at C7-T1 (cardio-accelerator) of the spinal cord in pithed SHR, suggesting that viprostol did not activate the presynaptic alpha-adrenoceptors.
(12) In pithed rats, the vasopressor response to dihydroergotoxine was reduced competitively by yohimbine, and non-competitively by nifedipine, but not by prazosin or methysergide, showing that the vasoconstriction is mediated by alpha 2-adrenoceptors.
(13) The antagonistic effects of a new inositol phosphate derivative, D-myoinositol-1,2,6-trisphosphate (PP56), on pressor responses to preganglionic sympathetic nerve stimulation and exogenously administered phenylephrine or neuropeptide Y (NPY) were investigated in vivo in the pithed rat.
(14) We conclude that in contrast to the increase in diastolic pressure elicited by B-HT 920, calcium channels are not involved in the cirazoline-induced pressor responses in the pithed cat.
(15) Acute or chronic adrenalectomy did not alter the pressor responses and chronotropic effect of angiotensin in the pithed rat.
(16) Habituated cells derived from inducible pith cells give rise to normal plants whose leaf and pith tissues require cytokinin for growth in culture.
(17) The endovenous perfusion of the splenic material in acidified and alkalinized forms caused significant increases of the mean blood pressure in normal, vagotomized and pithed rats, showing that, in contradiction to previous reports, changes in pH did not affect its hypertensive activity.
(18) The dose-response curves of three alpha-agonists noradrenaline, St 587 and B-HT 933 in pithed rats were shifted rightwards by pretreatment (i.v.
(19) In pithed rats, only pindolol produced a definite fall of blood pressure.
(20) The bradycardia was reduced but not blocked by pre-treatment with guanethidine, yohimbine, propranolol or pithing.
Stuff
Definition:
(v. t.) Material which is to be worked up in any process of manufacture.
(v. t.) The fundamental material of which anything is made up; elemental part; essence.
(v. t.) Woven material not made into garments; fabric of any kind; specifically, any one of various fabrics of wool or worsted; sometimes, worsted fiber.
(v. t.) Furniture; goods; domestic vessels or utensils.
(v. t.) A medicine or mixture; a potion.
(v. t.) Refuse or worthless matter; hence, also, foolish or irrational language; nonsense; trash.
(v. t.) A melted mass of turpentine, tallow, etc., with which the masts, sides, and bottom of a ship are smeared for lubrication.
(v. t.) Paper stock ground ready for use.
(n.) To fill by crowding something into; to cram with something; to load to excess; as, to stuff a bedtick.
(n.) To thrust or crowd; to press; to pack.
(n.) To fill by being pressed or packed into.
(n.) To fill with a seasoning composition of bread, meat, condiments, etc.; as, to stuff a turkey.
(n.) To obstruct, as any of the organs; to affect with some obstruction in the organs of sense or respiration.
(n.) To fill the skin of, for the purpose of preserving as a specimen; -- said of birds or other animals.
(n.) To form or fashion by packing with the necessary material.
(n.) To crowd with facts; to cram the mind of; sometimes, to crowd or fill with false or idle tales or fancies.
(n.) To put fraudulent votes into (a ballot box).
(v. i.) To feed gluttonously; to cram.
Example Sentences:
(1) She read geography at Oxford, where Benazir Bhutto (a future prime minister of Pakistan, assassinated in 2007) introduced May to her future husband, Philip May: "I hate to say this, but it was at an Oxford University Conservative Association disco… this is wild stuff.
(2) In October, an episode of South Park saw the whole town go gluten-free (the stuff, it was discovered, made one’s penis fly off).
(3) It’s good stuff.” Opening markets to US-made products overseas is one of the better things that could happen for US small business and their employees, said Obama.
(4) A Tory spokesman said: “This is feeble stuff from a party with no economic plan and a leader who just isn’t up it.
(5) The "fly on the wall" stuff is no more for the moment but, Andy, grab the opportunities when you can – a few years down the line when Cameron is on the lecture circuit and the rest of us are hanging up our cameras for good, you should have an unprecedented photographic record of a seat of power.
(6) He’s struck a few chords with the immigration stuff, and he’s managed to capture the most valuable asset in a campaign, which is the attention of the press.
(7) I don’t buy any of the horse race stuff,” Bush said Tuesday.
(8) Del Bosque had listened to the criticism, all that stuff about it being a negative tactic, and decided not to budge an inch, and who can blame him?
(9) Real people, by contrast, care more about their jobs, where they live, and the fuzzy stuff of security, happiness and a sense of belonging.
(10) He must have had PR training – didn’t it stretch to not saying stupid stuff?
(11) "A lot of this stuff we inherited and had to continue," a Downing Street source said.
(12) Updated at 4.05am BST 4.00am BST Dodgers 3 - Cardinals 0, top of 9th And so it's all up to Yadier Molina, the Cardinals catcher who is looking to get a rally going, no easy task against Jansen who looks to have his best stuff tonight.
(13) As one source close to the inquiry put it: “There was a hell of a lot of dirty stuff going on.” Two earlier Yard inquiries had failed to investigate the relevant notes in Mulcaire’s logs.
(14) He says he did write grown-up stuff – Joking Apart in the 90s and Coupling in the 00s, sitcoms that riffed on his own sexual history.
(15) There's a cute one comparing feelings to children: you don't want to let them drive, but equally you don't want to stuff them in the boot.
(16) Who hasn’t moved house and chucked a load of old stuff just because they can’t face ramming it back into the Ikea chest of drawers?
(17) Hidden City writer Karl Whitney on Dublin Read more And now for a pint of the black stuff Ireland’s capital is awash with history but no visit would be complete without a sample of the black stuff.
(18) 1.57pm BST Lap 36: Punchy stuff from Jules Bianchi up to 13th, literally bumping his way through Kobayashi on the inside.
(19) "Good stuff this from City as they're effectively playing with ten men," opines Paul Ruffley.
(20) If you pushed them on Hitler you got the most extraordinary stuff: "He was mah-vellous.