(n.) The soft spongy substance in the center of the stems of many plants and trees, especially those of the dicotyledonous or exogenous classes. It consists of cellular tissue.
(n.) The spongy interior substance of a feather.
(n.) The spinal cord; the marrow.
(n.) Hence: The which contains the strength of life; the vital or essential part; concentrated force; vigor; strength; importance; as, the speech lacked pith.
(v. t.) To destroy the central nervous system of (an animal, as a frog), as by passing a stout wire or needle up and down the vertebral canal.
Example Sentences:
(1) Finally, fosinopril had no effect on the pressor or chronotropic effects of norepinephrine (NE) or 1,1-dimethyl-4-phenylpiperinium (DMPP) or electrical stimulation of the sympathetic ganglia of pithed rats.
(2) Relatively weaker GUS activity was also detected in pith parenchyma.
(3) Both d- and l-amphetamine were also compared for their pressor and tachycardic activity in pithed rats.
(4) Intravenous administration of T-2 to pithed rats did not alter blood pressure or heart rate at a time when, in conscious rats, both blood pressure and heart rate were increased.
(5) Monoiodo-Ang II was found to be a potent, full agonist in in vivo bioassays and a more potent (2.5-fold) pressor agent than the native hormone Ang II in the pithed rat.
(6) APP 201-533 [3-amino-6-methyl-5-phenyl-2(1H)-pyridinone] was investigated in vivo in anesthetized and unanesthetized dogs and pithed open-chest cats and in vitro in guinea pig atria and papillary muscles, skinned muscle fibers from pig hearts, and rat myocardium.
(7) The effects of quinpirole, a specific dopamine DA2 receptor agonist, on autonomic nervous control of heart rate, were studied in normotensive pithed rats, by analysing its action on the tachycardia and bradycardia evoked by electrical stimulation of the cardioaccelerator (10 V; 1 ms; 0.5, 1, 3, 6 Hz) and vagus (10 V; 1 ms; 3, 6, 9 Hz) nerves respectively.
(8) Pith cells can shift from the C- to the C+ state by a process known as habituation.
(9) The pressor actions of ET3 and arginine vasopressin (AVP) were compared with one another in pithed rats in the presence of the calcium channel activator BAY K 8644 or the calcium channel antagonist nifedipine i.a.
(10) Both human endothelin 1 (ET1) and rat endothelin 3 (ET3) produced dose-dependent pressor effects in the pithed rat.
(11) Viprostol did not antagonize the tachycardia induced by stimulation of the discrete segments at C7-T1 (cardio-accelerator) of the spinal cord in pithed SHR, suggesting that viprostol did not activate the presynaptic alpha-adrenoceptors.
(12) In pithed rats, the vasopressor response to dihydroergotoxine was reduced competitively by yohimbine, and non-competitively by nifedipine, but not by prazosin or methysergide, showing that the vasoconstriction is mediated by alpha 2-adrenoceptors.
(13) The antagonistic effects of a new inositol phosphate derivative, D-myoinositol-1,2,6-trisphosphate (PP56), on pressor responses to preganglionic sympathetic nerve stimulation and exogenously administered phenylephrine or neuropeptide Y (NPY) were investigated in vivo in the pithed rat.
(14) We conclude that in contrast to the increase in diastolic pressure elicited by B-HT 920, calcium channels are not involved in the cirazoline-induced pressor responses in the pithed cat.
(15) Acute or chronic adrenalectomy did not alter the pressor responses and chronotropic effect of angiotensin in the pithed rat.
(16) Habituated cells derived from inducible pith cells give rise to normal plants whose leaf and pith tissues require cytokinin for growth in culture.
(17) The endovenous perfusion of the splenic material in acidified and alkalinized forms caused significant increases of the mean blood pressure in normal, vagotomized and pithed rats, showing that, in contradiction to previous reports, changes in pH did not affect its hypertensive activity.
(18) The dose-response curves of three alpha-agonists noradrenaline, St 587 and B-HT 933 in pithed rats were shifted rightwards by pretreatment (i.v.
(19) In pithed rats, only pindolol produced a definite fall of blood pressure.
(20) The bradycardia was reduced but not blocked by pre-treatment with guanethidine, yohimbine, propranolol or pithing.
Tenor
Definition:
(n.) A state of holding on in a continuous course; manner of continuity; constant mode; general tendency; course; career.
(n.) That course of thought which holds on through a discourse; the general drift or course of thought; purport; intent; meaning; understanding.
(n.) Stamp; character; nature.
(n.) An exact copy of a writing, set forth in the words and figures of it. It differs from purport, which is only the substance or general import of the instrument.
(n.) The higher of the two kinds of voices usually belonging to adult males; hence, the part in the harmony adapted to this voice; the second of the four parts in the scale of sounds, reckoning from the base, and originally the air, to which the other parts were auxillary.
(n.) A person who sings the tenor, or the instrument that play it.
Example Sentences:
(1) No, for all of its ugly tenor, that statement has long been true under the law; corporations have long existed as a concept by which business interests could have the legal standing of individuals.
(2) The discovery of troponin C and calmodulin set the tenor for understanding the intracellular mechanism of action of calcium.
(3) Abdullah reined in his base but the shift in the tenor of the fans was unmistakeable, especially after some of them tore down a portrait of Karzai.
(4) Macqueen plays up that view, and finds the tenor of his Eye different from that of Ingrams.
(5) In the young age group sexual activity was highest among the bass voices, in the middle and old age group tenors were most active.
(6) The idea caught on, and now the Doodlers have put their innovative spin on everything from Freddie Mercury (a video accompanied by the 1978 Queen hit Don’t Stop Me Now) to Jules Verne (the logo adapted to show the view from a submarine, inspired by Verne’s classic Twenty Thousand Leagues Under The Sea), and the tenor Luciano Pavarotti, whose animated likeness replaced the “L” on the Google logo for one day in 2007.
(7) | Lucia Graves Read more It was an attempt to resurrect the long-dead genre of vaudeville, only replacing acrobats with Rick Santorum and tenors with veterans.
(8) So incendiary were the interview's contents evidently deemed that it was practically smuggled out of the Vatican, with so few senior officials reportedly aware of its tenor that the consensus is that it has sent "shock waves" around the Catholic world.
(9) As compared to tenor singers higher testosterone and lower oestradiol plasma concentrations were measured in bass and baritone singers.
(10) Mr Woodhouse has an obsession with vitamin pills, Jane Fairfax plays the tenor saxophone and Frank Churchill has been living in Australia: meet the cast of the modern-day Emma, which is to be rewritten for the social media generation by Alexander McCall Smith .
(11) For the same excess pressure over threshold, the professional tenors produced 10-12 dB greater intensity than the male nonsingers, primarily because their peak airflow was much higher for the same pressure.
(12) These performances are splendid, but the principals are exceptional: Thompson finds vulnerability beneath Travers's spikes, and Hanks brings a steely tenor to Disney that prevents him from becoming completely gooey.
(13) Sometimes, says Costa, 74, Mario Lanza, the American tenor and Hollywood star would feature.
(14) We must fight for the real needs of the people | Bernie Sanders and James Clyburn Read more The tenor of such exchanges echoed Republican town halls in other states in recent months.
(15) Jay Kaplan, staff attorney at the LGBT project of the ACLU of Michigan, told the Guardian the law “flies in the face of the whole tenor” of the supreme court’s majority opinion on same-sex marriage.
(16) 18 February 2010 The PCC rejects the complaint , admitting it was "uncomfortable with the tenor of the columnist's remarks" but that censuring Moir and the Mail would represent "a slide towards censorship".
(17) In recent days, Westerwelle even intensified the tenor of his rhetoric.
(18) So many images are seared into the mind, from the sight of Ranieri proudly standing alongside Andrea Bocelli as the Italian tenor produced such a spine-tingling performance, to that wonderful and surreal moment later in the evening when Wes Morgan and his 64-year-old manager thrust the Premier League trophy into the night sky to a backdrop of fireworks and tears.
(19) In the Atlantic city of Mar del Plata, lyric tenor Darío Volonté, a survivor of the Belgrano, the cruiser on which 323 Argentinian sailors died after it was torpedoed by a British submarine, led a large crowd in the national anthem.
(20) As the audience arrived outside the Lincoln Center, protesters brandished signs with slogans such as “tenors and terrorists don’t mix”.