(n.) The soft spongy substance in the center of the stems of many plants and trees, especially those of the dicotyledonous or exogenous classes. It consists of cellular tissue.
(n.) The spongy interior substance of a feather.
(n.) The spinal cord; the marrow.
(n.) Hence: The which contains the strength of life; the vital or essential part; concentrated force; vigor; strength; importance; as, the speech lacked pith.
(v. t.) To destroy the central nervous system of (an animal, as a frog), as by passing a stout wire or needle up and down the vertebral canal.
Example Sentences:
(1) Finally, fosinopril had no effect on the pressor or chronotropic effects of norepinephrine (NE) or 1,1-dimethyl-4-phenylpiperinium (DMPP) or electrical stimulation of the sympathetic ganglia of pithed rats.
(2) Relatively weaker GUS activity was also detected in pith parenchyma.
(3) Both d- and l-amphetamine were also compared for their pressor and tachycardic activity in pithed rats.
(4) Intravenous administration of T-2 to pithed rats did not alter blood pressure or heart rate at a time when, in conscious rats, both blood pressure and heart rate were increased.
(5) Monoiodo-Ang II was found to be a potent, full agonist in in vivo bioassays and a more potent (2.5-fold) pressor agent than the native hormone Ang II in the pithed rat.
(6) APP 201-533 [3-amino-6-methyl-5-phenyl-2(1H)-pyridinone] was investigated in vivo in anesthetized and unanesthetized dogs and pithed open-chest cats and in vitro in guinea pig atria and papillary muscles, skinned muscle fibers from pig hearts, and rat myocardium.
(7) The effects of quinpirole, a specific dopamine DA2 receptor agonist, on autonomic nervous control of heart rate, were studied in normotensive pithed rats, by analysing its action on the tachycardia and bradycardia evoked by electrical stimulation of the cardioaccelerator (10 V; 1 ms; 0.5, 1, 3, 6 Hz) and vagus (10 V; 1 ms; 3, 6, 9 Hz) nerves respectively.
(8) Pith cells can shift from the C- to the C+ state by a process known as habituation.
(9) The pressor actions of ET3 and arginine vasopressin (AVP) were compared with one another in pithed rats in the presence of the calcium channel activator BAY K 8644 or the calcium channel antagonist nifedipine i.a.
(10) Both human endothelin 1 (ET1) and rat endothelin 3 (ET3) produced dose-dependent pressor effects in the pithed rat.
(11) Viprostol did not antagonize the tachycardia induced by stimulation of the discrete segments at C7-T1 (cardio-accelerator) of the spinal cord in pithed SHR, suggesting that viprostol did not activate the presynaptic alpha-adrenoceptors.
(12) In pithed rats, the vasopressor response to dihydroergotoxine was reduced competitively by yohimbine, and non-competitively by nifedipine, but not by prazosin or methysergide, showing that the vasoconstriction is mediated by alpha 2-adrenoceptors.
(13) The antagonistic effects of a new inositol phosphate derivative, D-myoinositol-1,2,6-trisphosphate (PP56), on pressor responses to preganglionic sympathetic nerve stimulation and exogenously administered phenylephrine or neuropeptide Y (NPY) were investigated in vivo in the pithed rat.
(14) We conclude that in contrast to the increase in diastolic pressure elicited by B-HT 920, calcium channels are not involved in the cirazoline-induced pressor responses in the pithed cat.
(15) Acute or chronic adrenalectomy did not alter the pressor responses and chronotropic effect of angiotensin in the pithed rat.
(16) Habituated cells derived from inducible pith cells give rise to normal plants whose leaf and pith tissues require cytokinin for growth in culture.
(17) The endovenous perfusion of the splenic material in acidified and alkalinized forms caused significant increases of the mean blood pressure in normal, vagotomized and pithed rats, showing that, in contradiction to previous reports, changes in pH did not affect its hypertensive activity.
(18) The dose-response curves of three alpha-agonists noradrenaline, St 587 and B-HT 933 in pithed rats were shifted rightwards by pretreatment (i.v.
(19) In pithed rats, only pindolol produced a definite fall of blood pressure.
(20) The bradycardia was reduced but not blocked by pre-treatment with guanethidine, yohimbine, propranolol or pithing.
Tith
Definition:
(a.) Tight; nimble.
Example Sentences:
(1) Retired neurosurgeon Ben Carson , who is currently positioned second in the polls behind Trump, was given respectful time to explain the medical consensus dismissing what many see as crackpot theories about vaccines and autism – but was only pressed briefly on his own arguably equally crackpot assertion that any form of progressive taxation amounts to socialism and the US should opt for a biblical tithe system instead.
(2) All five cell lines had small deposits of intramembraneous alkaline phosphatase in the plasma membrane and deposits associated tith the mitochondrial membranes and the endoplasmic reticulum that were not completely inhibited by phenylalanine or Levamisole.
(3) He dined with developers in private, at a huge property junket in Cannes called Mipim, and publicly announced his grand bargain with capital: they should be allowed to build as big as they wanted, as long as he could take a tithe of the proceeds to spend on such things as affordable housing.
(4) By the end of 2003, Christ Fellowship was the church where we regularly attended services,” he recalls in American Son, “and the church we tithed to as well.
(5) A request to his campaign to clarify whether he still tithes to the church was not returned at time of publication.
(6) But this is hardly what we think of as "social enterprise" – it looks more like a kind of feudalism, run on tithes and tributes and grudging sense of noblesse oblige .
(7) What's demolished: Harmondsworth Moor, Harmondsworth, and Longford - 950 homes, and the Tithe Barn and St Mary's Church in Harmondsworth, both sites of significant heritage value.
(8) This alone is an impressive list of publications and public awards, but is a mere tithe of Carpenter's extraordinary output, which also includes magnificently researched histories of the BBC Third programme, the postwar English satire movement, American writers in Paris between the wars, the Brideshead generation, and the 'angry young men', as well as an Oxford Companion to Children's Literature.
(9) But the Conservatives clearly don’t value all inheritances, for all their noise about the evils of inheritance tax, a tithe on extreme wealth that in practice afflicts barely anyone.
(10) He tithed, donating part of his salary to his local Pentecostal church, and fasted once a week.
(11) This is what coffee can be – what coffee is – that makes artisanal devotees travel, tithe and tip for what we could never, ever get at Starbucks .
(12) I'd like to see a movement of older people helping younger people and that might take all sorts of forms, like tithing part of your winter fuel allowance if you can afford to, or mentoring.
(13) Members are expected both to sell copies of the Nation’s paper, The Final Call, and submit tithes.
(14) On Wednesday airport authorities unveiled three proposals for a third runway, one of which would mean that St Mary's and a huge tithe barn next door would almost certainly be demolished along with hundreds of homes in Harmondsworth.
(15) Near Llantwit Major, the St Donat's Arts Centre ( stdonats.com ) – in an old tithe barn within St Donats Castle, formerly a home of William Randolph Hearst – puts on regular concerts, plays and exhibitions.
(16) Malcolm Muggeridge, in his book The Thirties, described the growth of the BBC in that decade (it had 4,233 employees by July 1939) thus: “The BBC came to pass silently, invisibly; like a coral reef, cells busily multiplying, until it was a vast structure … a society, with its king and lords and commoners, its laws and dossiers and revenue and easily suppressed insurrection …” Others think of it as like a religion: its foundations are faith and trust, and it will wither away when the congregations cease to believe in it (and pay their tithes to it).