(n.) A fixed pin or short axis, on the end of which a wheel or other body turns.
(n.) The end of a shaft or arbor which rests and turns in a support; as, the pivot of an arbor in a watch.
(n.) Hence, figuratively: A turning point or condition; that on which important results depend; as, the pivot of an enterprise.
(n.) The officer or soldier who simply turns in his place whike the company or line moves around him in wheeling; -- called also pivot man.
(v. t.) To place on a pivot.
Example Sentences:
(1) Excessive accumulation of hydrogen ions in the brain may play a pivotal role in initiating the necrosis seen in infarction and following hyperglycemic augmentation of ischemic brain damage.
(2) The function of motherese has become a pivotal issue in the language-learning literature.
(3) Glucose is the principal source for energy production in the brain, and undisturbed glucose metabolism is pivotally significant for normal function of this organ.
(4) Currently employed clinical indicators of perfusion provide inadequate warning of developing hazards caused by marginal perfusion in certain vital organs or "peripheral" tissues that are pivotal to postsurgical wound healing.
(5) Endobronchial biopsy and bronchial lavage studies following inhaled PAF did not show any increase in the number of activation of eosinophils, which are pivotal in the pathogenesis of BHR.
(6) Turkish police have stormed the offices of an opposition media group days before the country’s pivotal election, in a crackdown on companies linked to a US-based cleric and critic of President Recep Tayyip Erdoğan .
(7) It was the introduction of Aluko that proved pivotal.
(8) This article discusses the effect of existing statutes and case law on three pivotal questions: To what sort of information are people entitled?
(9) It has been generally accepted that the deregulation of oncogenes or their regulators play a pivotal role in progression of this prevalent disease.
(10) The fact that Fraser suggested Pinter write one of the pivotal scenes, in which Emma challenges Jerry to leave his wife, was a revelation, he says.
(11) Marine Rotational Force – Darwin” (MRF-D) is one of four American marine air ground task forces (MAGTFs) in the Asia-Pacific region, along with those in Guam, Hawaii and Okinawa, the sum of which make up a central strategic pillar of the pivot.
(12) Facebook Twitter Pinterest ‘I’m president, they’re not’: Donald Trump at rally in Washington Trump is “much more resilient” than his opponents allow, said Newt Gingrich, the former House speaker, before pivoting to a plug for his new book, Understanding Trump .
(13) Twitter has become pivotal in organising anti-government dissent in the past year: the Occupy Gezi movement, which marches against the recently passed internet censorship bill that allows the government to block any content within four hours without a court order, and the massive street protest and the funeral attended by hundreds of thousands after the death of 15-year-old Berkin Elvan , were initiated via social media.
(14) Verbal and non verbal communication skills (with the patient and the team) are pivotal in this approach; relatives are considered partners in the care of the patient and an essential element of the caring environment.
(15) This year will mark the start of a pivotal chapter for development as the UN finalises ambitious goals this autumn to improve all lives and secure a healthy planet.
(16) The 5' cap structure of eucaryotic mRNA plays a pivotal role in mRNA metabolism.
(17) Thirty years after one of the pivotal clashes in the miners' strike of 1984 when violent confrontations erupted at the Orgreave coking plant, the area outside Sheffield could barely look more different.
(18) Arthritic symptoms were present at operation in thirty patients, while thirty-four had no postoperative objective signs of pivot shift or instability.
(19) Two lines of evidence indicate that the general transcription factor TFIIB is a pivotal component in the mechanism by which an acidic activator functions.
(20) If cortical actin filaments are disrupted with dihydrocytochalasin B, processes form that are similar to those induced by dBcAMP suggesting that the disruption of the cortical actin network is the pivotal step in process formation.
Spindle
Definition:
(n.) The long, round, slender rod or pin in spinning wheels by which the thread is twisted, and on which, when twisted, it is wound; also, the pin on which the bobbin is held in a spinning machine, or in the shuttle of a loom.
(n.) A slender rod or pin on which anything turns; an axis; as, the spindle of a vane.
(n.) The shaft, mandrel, or arbor, in a machine tool, as a lathe or drilling machine, etc., which causes the work to revolve, or carries a tool or center, etc.
(n.) The vertical rod on which the runner of a grinding mill turns.
(n.) A shaft or pipe on which a core of sand is formed.
(n.) The fusee of a watch.
(n.) A long and slender stalk resembling a spindle.
(n.) A yarn measure containing, in cotton yarn, 15,120 yards; in linen yarn, 14,400 yards.
(n.) A solid generated by the revolution of a curved line about its base or double ordinate or chord.
(n.) Any marine univalve shell of the genus Rostellaria; -- called also spindle stromb.
(n.) Any marine gastropod of the genus Fusus.
(v. i.) To shoot or grow into a long, slender stalk or body; to become disproportionately tall and slender.
Example Sentences:
(1) A spindle cell sarcoma appeared 20 months after implantation of a pellet of 3-methylcholanthrene in the denervated foreleg of an adult frog, Rana pipiens.
(2) Actin is present in chromosomal spindle fibres, with consistent polarity.
(3) The aim was to clarify the nature of their constituent cells, specifically the giant ganglion-like cells and spindle cells, and to discuss the implications for histogenesis.
(4) Despite severe defects in the 1st or 2nd meiotic spindles in all mutants, no effect on mitosis was observed.
(5) The unsatisfactory smear showed atypical spindle cells.
(6) The cortical thresholds for contraction of m. extensor digitorum communis and for acceleration of the discharges of its muscle spindles have therefore been compared.2.
(7) Out of the remaining 14 cases six tumours consisted of epithelioid cells, one--spindle-shaped and seven were of mixed structure.
(8) Fibroblastic cells were characterized by their spindle shape, content of a mucopolysaccharide, their relative inability to synthesize infectious influenza virus, and production of a cell-associated noninfectious hemagglutinin.
(9) Germinal vesicle stage oocytes undergo perinuclear aggregation of acidic organelles during GVBD and these organelles subsequently disperse into the cell cortex as the first meiotic spindle migrates to the oocyte periphery.
(10) This is the first study identifying the birefringence of the spindle microtubules as well as three sets of microfilamentous structure in Dictyostelium.
(11) In reviewing recent progress concerning the motor system and drug action, the following subjects will be discussed on the basis of our data: 1) the mechanisms of action of mephenesin and baclofen, 2) baclofen and gamma-aminobutyric acid B (GABAB) receptor, 3) GABA-, benzodiazepine receptors, 4) control of spinal motor system by descending noradrenergic neuron, 5) pharmacology of the muscle spindle, and 6) pharmaco-metrics of centrally acting muscle relaxants.
(12) The V79 cells were treated for 30 min and in general, loss of a stainable spindle could be demonstrated at slightly higher concentrations than c-mitosis.
(13) Seven tumours were predominantly of blue and spindle-cell, fascicular type, resembling malignant peripheral nerve sheath tumour and at times monophasic synovial sarcoma.
(14) To our knowledge, peripheral adenocarcinoma of the lung with a spindle-cell component has not been described previously.
(15) H-protein altered the structure of the LMM paracrystals, especially the spindle-shaped ones.
(16) Isolated nuclei from green leaf tissue of tomato plants infected with potato spindle tuber viroid (PSTVd) were bound to microscope slides, fixed with formaldehyde and hybridized with biotinylated transcripts of cloned PSTVd cDNA.
(17) The wire functioned as a spindle along which the distraction of the osteotomized bone fragments was continued.
(18) It is suggested that contracting extrafusal muscle fibres can modulate the discharge pattern of spindle endings and contribute to the variability of discharge during a voluntary contraction.
(19) In the same subject, also the ratio between the number of the muscle spindles found in m. rectus dorsalis and that of m. levator palpebrae superioris was examined.
(20) We tested nine (cadmium chloride, chloral hydrate, colchicine, diazepam, econazole nitrate, hydroquinone, pyrimethamine, thiabendazole, thimerosal) of the 10 known or suspected spindle poisons of the coordinated programme to study aneuploidy induction sponsored by the Commission of the European Communities using Saccharomyces cerevisiae D61.M (mitotic chromosomal malsegregation system).