(a.) Sportive; gamboling; frolicsome; indulging a sportive fancy; humorous; merry; as, a playful child; a playful writer.
Example Sentences:
(1) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(2) The data indicate that ebselen is likely to be useful in the therapy of inflammatory conditions in which reactive oxygen species, such as peroxides, play an aetiological role.
(3) It involves creativity, understanding of art form and the ability to improvise in the highly complex environment of a care setting.” David Cameron has boosted dementia awareness but more needs to be done Read more She warns: “To effect a cultural change in dementia care requires a change of thinking … this approach is complex and intricate, and can change cultural attitudes by regarding the arts as central to everyday life of the care home.” Another participant, Mary*, a former teacher who had been bedridden for a year, read plays with the reminiscence arts practitioner.
(4) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(5) Mike Ashley told Lee Charnley that maybe he could talk with me last week but I said: ‘Listen, we cannot say too much so I think it’s better if we wait.’ The message Mike Ashley is sending is quite positive, but it was better to talk after we play Tottenham.” Benítez will ask Ashley for written assurances over his transfer budget, control of transfers and other spheres of club autonomy, but can also reassure the owner that the prospect of managing in the second tier holds few fears for him.
(6) Because many wnt genes are also expressed in the lung, we have examined whether the wnt family member wnt-2 (irp) plays a role in lung development.
(7) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(8) Michael Caine was his understudy for the 1959 play The Long and the Short and the Tall at the Royal Court Theatre.
(9) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
(10) In concert with TF expressed by monocytes and macrophages this endothelial cell procoagulant activity may play a role in the pathogenesis of thrombotic disease.
(11) To determine whether or not the glycan moieties in hTPO play a role in the disease-associated epitopes in Hashimoto's thyroiditis, radiolabeled recombinant hTPO was immunoprecipitated after digestion with N-glycanase.
(12) Immunohistochemical observation of myoepithelial cells with monoclonal antibody from human mammalian cancer suggested that these cells play an important role in the process of glandular ducts formation.
(13) Anti-human factor V IgG decreased this enhanced thrombin formation in the presence of platelets, indicating that factor V from platelets was playing an important role in thrombin formation.
(14) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
(15) The playing fields on which all those players began their journeys have been underfunded for years and are now facing a renewed crisis because of cuts to local authority budgets.
(16) The behaviour of DAO suggests that the enzyme plays an important role in the control of intracellular diamine concentration.
(17) It was with unanimous consent.” He denied that Trump’s tweets had played a part, saying: “No, no, no.
(18) When you have been out for a month you need to prepare properly before you come back.” Pellegrini will make his own assessment of Kompany’s fitness before deciding whether to play him in the Bournemouth game, which he is careful to stress may not be the foregone conclusion the league table might suggest.
(19) Photograph: Guardian The research also compiled data covered by a wider definition of tax haven, including onshore jurisdictions such as the US state of Delaware – accused by the Cayman islands of playing "faster and looser" even than offshore jurisdictions – and the Republic of Ireland, which has come under sustained pressure from other EU states to reform its own low-tax, light-tough, regulatory environment.
(20) Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.
Sober
Definition:
(superl.) Temperate in the use of spirituous liquors; habitually temperate; as, a sober man.
(superl.) Not intoxicated or excited by spirituous liquors; as, the sot may at times be sober.
(superl.) Not mad or insane; not wild, visionary, or heated with passion; exercising cool, dispassionate reason; self-controlled; self-possessed.
(superl.) Not proceeding from, or attended with, passion; calm; as, sober judgment; a man in his sober senses.
(superl.) Serious or subdued in demeanor, habit, appearance, or color; solemn; grave; sedate.
(v. t.) To make sober.
(v. i.) To become sober; -- often with down.
Example Sentences:
(1) It's typically sober and elegant, and Cotillard excels in a nervy, vulnerable role.
(2) Read Rachel’s full story Facebook Twitter Pinterest Chris Owen: ‘I’ve been sober for six years now, and I don’t miss alcohol.’ Photograph: Graeme Robertson for the Guardian I spent my 20s playing Russian roulette with alcohol The NHS has been there time and time again for Chris Owen, who battled alcoholism throughout his 20s.
(3) Anthony Wells, director of YouGov’s political and social research team, said: “While there will be speculation about whether this movement is connected to the tragic death of Jo Cox, we do not think that it is... We are now in the final week of the referendum campaign and the swing back towards the status quo appears to be in full force.” EU referendum voters unconvinced by scare tactics: ‘I just want to do what’s right’ Read more Today, both sides will resume their battle to capture the votes of the undecided and to persuade people to switch sides, though both the Leave and Remain camps say that the manner of their campaigning will be more sober and less combative.
(4) Previous research has found a relationship between increased quantity of alcohol usually consumed per drinking occasion and decreased sober cognitive performance.
(5) "Yet the sobering fact remains that a transition to a low-carbon, inclusive green economy is happening far too slowly and the opportunity for meeting the 44 gigatonne target is narrowing annually," Steiner said.
(6) The haemostatic imbalance normalizes within two or three weeks of soberness while the immune system requires about two months to recover.
(7) Chambers claims she became extremely intoxicated while her ex-boyfriend remained much more sober, and says she has no memory of him having sex with her that night.
(8) Therefore, the presence of pulmonary emboli in association with sagittal sinus thrombosis mandates a sober assessment of the need of anticoagulation therapy in the absence of obvious contraindication.
(9) Mutual intoxication was a feature in 44% of the cases and in 34% both participants were sober.
(10) Impulsive and bonhomous, Saakashvili, meanwhile, is clearly the temperamental opposite of Putin, the sober and clinical former KGB colonel.
(11) Barton rubs Old Firm up the wrong way Joey Barton apologises ‘unreservedly’ after being sent home by Rangers Read more The phrase “Joey Barton Twitter storm” is pretty much a tautology, so it was no surprise that his decision to sign for Rangers in May had social media in a kerfuffle when his 2012 tweet – “I am a Celtic fan” – was dredged up so that it might be subject to calm and sober scrutiny from all concerned.
(12) And yet here I am today, a sober, emancipated, successful and happy woman.
(13) After all, on any sober calculation of relative sins, HSBC's dealings with Mexican drug bandits were surely several leagues more serious than other banks' Libor-rigging scandals.
(14) In the swinging 1960s, Peck's sober style seemed a little out of place, though he appeared in a couple of flashy Hitchcockian thrillers, Mirage (1965) and Arabesque (1966), and adapted to the new Hollywood as best he could, looking rather bothered as the father of a demon in The Omen (1976).
(15) Alcoholics reported more anger and aggression when drinking than when sober and this effect was greatest among individuals with a history of childhood aggression.
(16) She observed soberly that "the moment human beings lacked their own government and had to fall back upon their minimum rights, no authority was left to protect them and no institution was willing to guarantee them … Loss of national rights was identical with loss of human rights … The rights of man, supposedly inalienable, proved to be unenforceable … whenever people appeared who were no longer citizens of any sovereign state."
(17) It's not the most groundbreaking piece of research, but I did find it both instructive and sobering.
(18) In a year that will be punctuated by sober reflection and a series of commemorative occasions, it is tempting to assume a certain inevitability to events, especially when looking at them through the prism of hindsight.
(19) Even in alcoholics who have been sober for a long time, increased cardiac output is very common and these changes are similar to those seen in some patients with labile hypertension.
(20) He was a vegan, sober, nonsexual God-botherer partying in the blood-soaked Meatpacking District with the sex-and-druggers.